DK51489A - Indolcarbazolderivater og farmakologisk uskadelige salte deraf, deres fremstilling og anvendelse - Google Patents

Indolcarbazolderivater og farmakologisk uskadelige salte deraf, deres fremstilling og anvendelse

Info

Publication number
DK51489A
DK51489A DK051489A DK51489A DK51489A DK 51489 A DK51489 A DK 51489A DK 051489 A DK051489 A DK 051489A DK 51489 A DK51489 A DK 51489A DK 51489 A DK51489 A DK 51489A
Authority
DK
Denmark
Prior art keywords
atoms
group
radical
denote
hydrogen
Prior art date
Application number
DK051489A
Other languages
English (en)
Other versions
DK51489D0 (da
Inventor
Juergen Kleinschroth
Johannes Hartenstein
Hubert Barth
Christoph Schaechtele
Claus Rudolph
Guenter Weinheimer
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of DK51489D0 publication Critical patent/DK51489D0/da
Publication of DK51489A publication Critical patent/DK51489A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DK051489A 1988-02-06 1989-02-03 Indolcarbazolderivater og farmakologisk uskadelige salte deraf, deres fremstilling og anvendelse DK51489A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3803620A DE3803620A1 (de) 1988-02-06 1988-02-06 Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK51489D0 DK51489D0 (da) 1989-02-03
DK51489A true DK51489A (da) 1989-08-07

Family

ID=6346797

Family Applications (1)

Application Number Title Priority Date Filing Date
DK051489A DK51489A (da) 1988-02-06 1989-02-03 Indolcarbazolderivater og farmakologisk uskadelige salte deraf, deres fremstilling og anvendelse

Country Status (16)

Country Link
EP (1) EP0328000B1 (da)
JP (1) JP2866096B2 (da)
KR (1) KR890013035A (da)
CN (1) CN1035667A (da)
AT (1) ATE117304T1 (da)
AU (1) AU616468B2 (da)
CA (1) CA1337767C (da)
DD (1) DD283394A5 (da)
DE (2) DE3803620A1 (da)
DK (1) DK51489A (da)
ES (1) ES2066798T3 (da)
GR (1) GR3015194T3 (da)
HU (1) HU203758B (da)
IE (1) IE65256B1 (da)
PT (1) PT89623B (da)
ZA (1) ZA89861B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3010675B2 (ja) * 1989-03-23 2000-02-21 萬有製薬株式会社 抗腫瘍性物質ｂｅ―１３７９３ｃ
US5618809A (en) * 1989-12-14 1997-04-08 Schering Corporation Indolocarbazoles from saccharothrix aerocolonigenes copiosa subsp. nov SCC 1951 ATCC 53856
AU7035991A (en) * 1989-12-14 1991-07-18 Schering Corporation Indolocarbazoles from saccharothrix aerocolonigenes subsp. copiosa subsp. nov. scc 1951 atcc 53856
DE3942296A1 (de) * 1989-12-21 1991-06-27 Goedecke Ag Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung
US5668271A (en) * 1991-11-29 1997-09-16 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5591842A (en) * 1991-11-29 1997-01-07 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
ATE175873T1 (de) * 1992-03-20 1999-02-15 Wellcome Found Weitere indolderivate mit antiviraler wirkung
DE4243321A1 (de) * 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
US5721230A (en) * 1993-05-10 1998-02-24 Hoffmann-La Roche Inc. Substituted pyrroles
ES2118414T3 (es) * 1993-05-28 1998-09-16 Cephalon Inc Utilizacion de derivados del indolocarbazol para el tratamiento de la prostata.
US5468872A (en) * 1993-09-16 1995-11-21 Cephalon, Inc. K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
US5723456A (en) * 1993-12-07 1998-03-03 Eli Lilly & Company Therapeutic treatment for cardiovascular diseases
CN1050844C (zh) * 1993-12-07 2000-03-29 伊莱利利公司 蛋白激酶ｃ抑制剂
US5541347A (en) * 1993-12-07 1996-07-30 Eli Lilly And Company Synthesis of bisindolylmaleimides
IL111851A (en) * 1993-12-07 1998-09-24 Lilly Co Eli Improved synthesis of bisindolylsimilides and process for its preparation
US5843935A (en) * 1993-12-07 1998-12-01 Eli Lilly And Company Protein kinase C inhibitors
SI0817627T1 (da) * 1993-12-23 2005-08-31 Lilly Co Eli
US5804564A (en) * 1994-05-09 1998-09-08 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US5922860A (en) * 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US5481003A (en) * 1994-06-22 1996-01-02 Eli Lilly And Company Protein kinase C inhibitors
US5491242A (en) * 1994-06-22 1996-02-13 Eli Lilly And Company Protein kinase C inhibitors
CA2245029A1 (en) 1998-03-13 1999-09-13 University Of British Columbia Granulatimide compounds as g2 checkpoint inhibitors
DE69911935T3 (de) * 1998-03-13 2008-02-07 The University Of British Columbia, Vancouver Granulatimide-derivate zur behandlung von krebs
US6653290B2 (en) 2000-10-06 2003-11-25 Bristol-Myers Squibb Company Tumor proliferation inhibitors
WO2002077255A1 (en) 2001-03-22 2002-10-03 Bristol-Myers Squibb Company Topoisomerase i selective cytotoxic sugar derivatives of indolopyrrolocarbazoles
CA2393720C (en) 2002-07-12 2010-09-14 Eli Lilly And Company Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
CN117486782A (zh) * 2023-12-29 2024-02-02 中国医学科学院药用植物研究所 一种n-取代咔唑衍生物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62155284A (ja) * 1985-12-27 1987-07-10 Kyowa Hakko Kogyo Co Ltd 生理活性物質ｋ−２５２の誘導体
US4737496A (en) * 1986-10-01 1988-04-12 Ciba-Geigy Corporation 1,3,4,16b-tetrahydro-2H,10H-indolo[2,1-c]pyrazino-[1,2-a][1,4]benzodiazepines useful as serotonin-2 receptor antagonists

Also Published As

Publication number Publication date
IE890359L (en) 1989-08-06
AU616468B2 (en) 1991-10-31
ZA89861B (en) 1989-11-29
HU203758B (en) 1991-09-30
JPH02149520A (ja) 1990-06-08
DE58908892D1 (de) 1995-03-02
ATE117304T1 (de) 1995-02-15
GR3015194T3 (en) 1995-05-31
CN1035667A (zh) 1989-09-20
KR890013035A (ko) 1989-09-21
PT89623B (pt) 1994-02-28
JP2866096B2 (ja) 1999-03-08
EP0328000A2 (de) 1989-08-16
DE3803620A1 (de) 1989-08-17
DK51489D0 (da) 1989-02-03
CA1337767C (en) 1995-12-19
IE65256B1 (en) 1995-10-18
EP0328000A3 (de) 1991-04-03
AU2960789A (en) 1989-08-10
ES2066798T3 (es) 1995-03-16
EP0328000B1 (de) 1995-01-18
DD283394A5 (de) 1990-10-10
PT89623A (pt) 1989-10-04

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment