ES8707972A1 - Un procedimiento para la preparacion de nuevos esteroides 11-b-sustituidos. - Google Patents
Un procedimiento para la preparacion de nuevos esteroides 11-b-sustituidos.Info
- Publication number
- ES8707972A1 ES8707972A1 ES555298A ES555298A ES8707972A1 ES 8707972 A1 ES8707972 A1 ES 8707972A1 ES 555298 A ES555298 A ES 555298A ES 555298 A ES555298 A ES 555298A ES 8707972 A1 ES8707972 A1 ES 8707972A1
- Authority
- ES
- Spain
- Prior art keywords
- steroids
- beta
- ofch2
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858513723A GB8513723D0 (en) | 1985-05-31 | 1985-05-31 | 11-beta substituted steroids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8707972A1 true ES8707972A1 (es) | 1987-09-01 |
| ES555298A0 ES555298A0 (es) | 1987-09-01 |
Family
ID=10579949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES555298A Expired ES8707972A1 (es) | 1985-05-31 | 1986-05-23 | Un procedimiento para la preparacion de nuevos esteroides 11-b-sustituidos. |
Country Status (21)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0289073B1 (en) * | 1987-04-24 | 1991-11-27 | Akzo N.V. | Novel 11-aryloestrane and 11-arylpregnane derivatives |
| ATE85342T1 (de) * | 1987-12-12 | 1993-02-15 | Akzo Nv | 11-arylsteroid-derivate. |
| FR2665901B2 (fr) * | 1989-02-24 | 1994-07-29 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments. |
| FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
| FR2701262B1 (fr) * | 1993-02-05 | 1995-03-24 | Roussel Uclaf | Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires. |
| TWI265167B (en) * | 1999-11-29 | 2006-11-01 | Akzo Nobel Nv | 3-methylene steroid derivatives |
| DE19961219A1 (de) * | 1999-12-15 | 2001-07-19 | Jenapharm Gmbh | 11beta-Phenylestratrien-Derivate mit Fluoralkylgruppen in der aromatischen Seitenkette, deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| TW200531977A (en) | 2004-03-25 | 2005-10-01 | Akzo Nobel Nv | Progesterone receptor modulators |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH488682A (de) * | 1965-07-30 | 1970-04-15 | Ciba Geigy | Verfahren zur Herstellung von 4,9,11-Trienen der 19-Nor-androstanreihe |
| FR205F (enrdf_load_stackoverflow) * | 1965-10-22 | |||
| FR5913M (enrdf_load_stackoverflow) * | 1965-12-02 | 1968-04-01 | ||
| NL128375C (enrdf_load_stackoverflow) * | 1966-02-18 | |||
| FR2054527B1 (enrdf_load_stackoverflow) * | 1969-07-28 | 1973-06-08 | Roussel Uclaf | |
| FR2054525B1 (enrdf_load_stackoverflow) * | 1969-07-28 | 1973-01-12 | Roussel Uclaf | |
| FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
| ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| FR2522328B1 (fr) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
| AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
-
1985
- 1985-05-31 GB GB858513723A patent/GB8513723D0/en active Pending
-
1986
- 1986-05-23 ES ES555298A patent/ES8707972A1/es not_active Expired
- 1986-05-27 HU HU862228A patent/HU197925B/hu not_active IP Right Cessation
- 1986-05-27 GB GB08612866A patent/GB2175905B/en not_active Expired
- 1986-05-28 IL IL78957A patent/IL78957A/xx unknown
- 1986-05-28 CH CH2152/86A patent/CH669385A5/de not_active IP Right Cessation
- 1986-05-28 FR FR8607660A patent/FR2582654B1/fr not_active Expired
- 1986-05-28 DE DE19863617883 patent/DE3617883A1/de not_active Withdrawn
- 1986-05-28 NZ NZ216325A patent/NZ216325A/xx unknown
- 1986-05-28 IT IT20598/86A patent/IT1190014B/it active
- 1986-05-28 PT PT82665A patent/PT82665B/pt not_active IP Right Cessation
- 1986-05-29 AU AU58062/86A patent/AU587031B2/en not_active Ceased
- 1986-05-29 SE SE8602449A patent/SE8602449L/ not_active Application Discontinuation
- 1986-05-29 GR GR861405A patent/GR861405B/el unknown
- 1986-05-29 DK DK251386A patent/DK251386A/da not_active Application Discontinuation
- 1986-05-29 NL NL8601387A patent/NL8601387A/nl not_active Application Discontinuation
- 1986-05-29 FI FI862278A patent/FI862278A7/fi not_active Application Discontinuation
- 1986-05-29 SU SU864027509A patent/SU1508963A3/ru active
- 1986-05-30 ZA ZA864065A patent/ZA864065B/xx unknown
- 1986-05-30 BE BE0/216722A patent/BE904846A/fr not_active IP Right Cessation
- 1986-05-30 JP JP61123893A patent/JPS6212796A/ja active Pending
- 1986-05-30 KR KR1019860004283A patent/KR860009035A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NZ216325A (en) | 1989-01-27 |
| IT8620598A1 (it) | 1987-11-28 |
| BE904846A (fr) | 1986-12-01 |
| FI862278A7 (fi) | 1986-12-01 |
| IL78957A0 (en) | 1986-09-30 |
| IT1190014B (it) | 1988-02-10 |
| FR2582654B1 (fr) | 1988-06-03 |
| FI862278A0 (fi) | 1986-05-29 |
| DK251386D0 (da) | 1986-05-29 |
| GB8612866D0 (en) | 1986-07-02 |
| JPS6212796A (ja) | 1987-01-21 |
| PT82665A (en) | 1986-06-01 |
| ES555298A0 (es) | 1987-09-01 |
| HU197925B (en) | 1989-06-28 |
| FR2582654A1 (fr) | 1986-12-05 |
| GB2175905A (en) | 1986-12-10 |
| PT82665B (pt) | 1988-08-17 |
| SE8602449D0 (sv) | 1986-05-29 |
| AU5806286A (en) | 1986-12-04 |
| SU1508963A3 (ru) | 1989-09-15 |
| KR860009035A (ko) | 1986-12-19 |
| ZA864065B (en) | 1987-01-28 |
| SE8602449L (sv) | 1986-12-01 |
| GB8513723D0 (en) | 1985-07-03 |
| DK251386A (da) | 1986-12-01 |
| GB2175905B (en) | 1989-01-18 |
| IL78957A (en) | 1990-11-29 |
| HUT44575A (en) | 1988-03-28 |
| IT8620598A0 (it) | 1986-05-28 |
| GR861405B (en) | 1986-09-26 |
| NL8601387A (nl) | 1986-12-16 |
| DE3617883A1 (de) | 1986-12-04 |
| CH669385A5 (enrdf_load_stackoverflow) | 1989-03-15 |
| AU587031B2 (en) | 1989-08-03 |
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