SE8205698D0 - N-(4-(3-aminopropyl)aminobutyl-2-(omega-guanidinofettsyra-amido)-2-substituerad-etanamid, salt derav och forfarande for framstellning derav - Google Patents

N-(4-(3-aminopropyl)aminobutyl-2-(omega-guanidinofettsyra-amido)-2-substituerad-etanamid, salt derav och forfarande for framstellning derav

Info

Publication number
SE8205698D0
SE8205698D0 SE8205698A SE8205698A SE8205698D0 SE 8205698 D0 SE8205698 D0 SE 8205698D0 SE 8205698 A SE8205698 A SE 8205698A SE 8205698 A SE8205698 A SE 8205698A SE 8205698 D0 SE8205698 D0 SE 8205698D0
Authority
SE
Sweden
Prior art keywords
aminobutyl
aminopropyl
amido
omega
substituted
Prior art date
Application number
SE8205698A
Other languages
English (en)
Other versions
SE452006B (sv
SE8205698L (sv
Inventor
H Umezawa
T Takeuchi
S Kondo
H Iinuma
D Ikeda
T Nakamura
A Fujii
Original Assignee
Zaidan Hojin Biseibutsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zaidan Hojin Biseibutsu filed Critical Zaidan Hojin Biseibutsu
Publication of SE8205698D0 publication Critical patent/SE8205698D0/sv
Publication of SE8205698L publication Critical patent/SE8205698L/sv
Publication of SE452006B publication Critical patent/SE452006B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
SE8205698A 1981-10-08 1982-10-06 N-/4(3-aminopropyl)aminobutyl/-2-(omega-guanidinofettsyraamido)-2-substituerad etanamid, salt derav och forfarande for framstellning derav SE452006B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56159503A JPS5862152A (ja) 1981-10-08 1981-10-08 Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法

Publications (3)

Publication Number Publication Date
SE8205698D0 true SE8205698D0 (sv) 1982-10-06
SE8205698L SE8205698L (sv) 1983-04-09
SE452006B SE452006B (sv) 1987-11-09

Family

ID=15695187

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8205698A SE452006B (sv) 1981-10-08 1982-10-06 N-/4(3-aminopropyl)aminobutyl/-2-(omega-guanidinofettsyraamido)-2-substituerad etanamid, salt derav och forfarande for framstellning derav

Country Status (19)

Country Link
US (3) US4518532A (sv)
JP (1) JPS5862152A (sv)
KR (1) KR870000656B1 (sv)
AT (1) AT393680B (sv)
AU (1) AU554489B2 (sv)
BE (1) BE894651A (sv)
CA (1) CA1187513A (sv)
CH (1) CH653015A5 (sv)
CS (1) CS268654B2 (sv)
DE (1) DE3236725A1 (sv)
DK (1) DK166080C (sv)
ES (2) ES516258A0 (sv)
FR (1) FR2514350B1 (sv)
GB (1) GB2111480B (sv)
HU (1) HU187417B (sv)
IT (1) IT1189373B (sv)
NL (1) NL193107C (sv)
SE (1) SE452006B (sv)
YU (1) YU44678B (sv)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS60181056A (ja) * 1984-02-29 1985-09-14 Takara Shuzo Co Ltd Ν−〔４−（３−アミノプロピル）アミノブチル〕−２，２−ジヒドロキシエタンアミドの製造法
JPS60185758A (ja) * 1984-03-02 1985-09-21 Microbial Chem Res Found フエニレン基を有するスパガリン関連化合物およびその製造法
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤
JPS61165322A (ja) * 1985-01-14 1986-07-26 Microbial Chem Res Found スパガリン類の注射用凍結乾燥製剤
JPH0742268B2 (ja) * 1985-08-27 1995-05-10 財団法人微生物化学研究会 フエニレン基を有するスパガリン類縁化合物及びその製造法
EP0241797B1 (en) * 1986-04-04 1991-06-12 Microbial Chemistry Research Foundation Novel spergualin-related compounds and process for producing the same
JP2605762B2 (ja) * 1986-12-10 1997-04-30 武田薬品工業株式会社 δ−ハイドロキシ−β−リジン誘導体およびその製造法
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions
JPH0776204B2 (ja) * 1988-07-01 1995-08-16 寳酒造株式会社 スパガリン類の精製法
US4990536A (en) * 1989-04-03 1991-02-05 Nippon Kayaku Kabushiki Kaisha Immunopotentiator and spergualin-related compound therefor
US5162581A (en) * 1989-05-29 1992-11-10 Takaru Shuzo Co., Ltd. Crystalline deoxyspergualin, process for its preparation and suppository containing the same
YU48230B (sh) * 1989-05-29 1997-08-22 Takara Shuzo Co.Ltd. Kristalni deoksispergvalin i postupak za njegovo pripremanje
JPH078846B2 (ja) * 1989-05-29 1995-02-01 寳酒造株式会社 塩酸デオキシスパガリンのβ型結晶及びその製造方法
US5196453A (en) * 1989-05-29 1993-03-23 Takara Shuzo Co., Ltd. Crystalline deoxyspergualin, process for its preparation and suppository containing the same
EP0467280B1 (en) * 1990-07-20 1994-09-28 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compound and use thereof
WO1994004140A1 (en) * 1992-08-19 1994-03-03 Nippon Kayaku Kabushiki Kaisha Antiprotozoan drug
CA2183917A1 (en) * 1995-09-26 1997-03-27 Xuebao Wang Preparation of optically active (s)-(-) and (r)-(+)- deoxyspergualin and novel intermediates thereof
EP2332522A3 (en) 1998-03-19 2011-12-07 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
US20020142000A1 (en) * 1999-01-15 2002-10-03 Digan Mary Ellen Anti-CD3 immunotoxins and therapeutic uses therefor
US6656917B1 (en) 1999-06-30 2003-12-02 Marker Gene Technologies, Inc. Compositions and methods for targeted enzymatic release of cell regulatory compounds
US8716558B2 (en) 1999-06-30 2014-05-06 Marker Gene Technologies, Inc. Method of altering glycosylation of proteins in response to nojirimycin glucuronide in a plant cell expressing glucuronidase
JP2005531391A (ja) * 2002-06-27 2005-10-20 微創医療器械（上海）有限公司 薬剤放出ステント
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
AU2011276254B2 (en) 2010-07-09 2016-11-03 James Trinca Green Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
JP6508944B2 (ja) 2012-02-15 2019-05-08 サイデックス・ファーマシューティカルズ・インコーポレイテッド シクロデキストリン誘導体のための製造方法
CA2865950C (en) 2012-02-28 2016-12-20 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
MX360192B (es) 2012-10-22 2018-10-24 Cydex Pharmaceuticals Inc Composiciones de ciclodextrinas alquiladas y procesos para preparar y usar las mismas.
US10851184B2 (en) 2014-08-22 2020-12-01 Cydex Pharmaceuticals, Inc. Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799988A (en) * 1969-04-02 1974-03-26 Taiho Pharmaceutical Co Ltd {107 -guanidino acid diamide derivatives and manufacturing the same
JPS5748957A (en) * 1980-09-08 1982-03-20 Microbial Chem Res Found Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
JPS57192347A (en) * 1981-05-18 1982-11-26 Microbial Chem Res Found N-(4-(3-aminopropyl)aminobutyl)-2,2-dihydroxyethanamide and its synthesis
JPS57185254A (en) * 1981-05-11 1982-11-15 Microbial Chem Res Found Novel carcinostatic substances and their preparation
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
US4525299A (en) * 1983-05-10 1985-06-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai (-)-15-Deoxyspergualin, process for the preparation thereof, and intermediate of the same

Also Published As

Publication number Publication date
ES8504690A1 (es) 1985-04-16
DK166080B (da) 1993-03-08
FR2514350A1 (fr) 1983-04-15
ES526501A0 (es) 1985-04-16
ES8402558A1 (es) 1984-02-01
IT1189373B (it) 1988-02-04
CA1187513A (en) 1985-05-21
CH653015A5 (de) 1985-12-13
FR2514350B1 (fr) 1985-10-25
AU554489B2 (en) 1986-08-21
US4518532A (en) 1985-05-21
YU227682A (en) 1985-06-30
BE894651A (fr) 1983-01-31
YU44678B (en) 1990-12-31
CS268654B2 (en) 1990-04-11
IT8249228A0 (it) 1982-10-07
CS717982A2 (en) 1989-08-14
AU8912182A (en) 1983-04-14
US4983328A (en) 1991-01-08
NL8203874A (nl) 1983-05-02
ATA369682A (de) 1991-05-15
JPS5862152A (ja) 1983-04-13
GB2111480A (en) 1983-07-06
US4658058A (en) 1987-04-14
HU187417B (en) 1986-01-28
DK166080C (da) 1993-08-02
SE452006B (sv) 1987-11-09
NL193107C (nl) 1998-11-03
GB2111480B (en) 1985-03-13
KR840001952A (ko) 1984-06-07
KR870000656B1 (ko) 1987-04-04
AT393680B (de) 1991-11-25
DE3236725C2 (sv) 1991-01-24
DK445182A (da) 1983-04-09
ES516258A0 (es) 1984-02-01
JPS6123183B2 (sv) 1986-06-04
DE3236725A1 (de) 1983-04-28
SE8205698L (sv) 1983-04-09
NL193107B (nl) 1998-07-01

Similar Documents

Publication Publication Date Title
SE8205698D0 (sv) N-(4-(3-aminopropyl)aminobutyl-2-(omega-guanidinofettsyra-amido)-2-substituerad-etanamid, salt derav och forfarande for framstellning derav
NL300396I1 (nl) Nieuwe derivaten met naftalinestructuren, werkwijze voor de bereiding ervan en de farmaceutische preparaten die deze bevatten
PT99135A (pt) Processo para a preparacao de derivados de piperazina
ES523689A0 (es) Procedimiento para preparar derivados de piperazina.
ES526765A0 (es) Procedimiento para preparar derivados de 2-amino-3-acilamino-6-bencilamino-piridina
SE7714592L (sv) Cyklopentan-1-aminer, forfarande for framstellning derav och medel innehallande dessa foreningar
KR900004658A (ko) 이치환 벤질아민, 그의 제조방법, 약제로서의 그의 용도 및 그의 합성 약제
ES405942A1 (es) Procedimiento para la preparacion de 2-fenilimino-imidazo- lidinas.
ES8308543A1 (es) "procedimiento para la preparacion de nuevas 2-fenil-2-(piridiloxi)-etilaminas sustituidas".
ES524990A0 (es) Procedimiento para preparar derivados de tieno-tiazol
ES535201A0 (es) Procedimiento para la obtencion deesteres sustituidos de tiazolidinilo de acidos minerales
FI890187A0 (fi) Foerfarande foer framstaellning av hydroxialkylerande foereningar, saolunda erhaollna nya foereningar och deras anvaendning.
ES550846A0 (es) Procedimiento para la obtencion de n-(fosfonometilglicil)sulfonilaminas de efecto herbicida.
MX11976A (es) Procedimiento para preparar derivados de 1-benzoil-2-oxo-5-alcoxi-pirrolidina y producto obtenido.
ES466867A1 (es) Procedimiento para la obtencion de 2,4-diclorofenil-imidazo-lil-etanonas y etanoles.
PT80993A (fr) Procede de preparation d'un derive de 1-(aminophenyl)-2-amino- -athanone
SE7910387L (sv) 7alfa-metoxicefalosporinderivat och forfarande for framstellning derav
ES8200658A1 (es) Procedimiento para la preparacion de sales de alcohileter- isotiuronio
SE8200679L (sv) 1-bensyl-4-(4-(2-pyrimidinylamino) bensyl 1-2,3-dioxopiperazinderivat, salter derav, forfarande for framstellning derav och karcinostatiska medel der de ingar
SE8303719D0 (sv) Novel eburnane oxime derivatives and process for preparing same
SE8005260L (sv) Nya isokinolinderivat samt framstellning derav
ES484086A1 (es) Procedimiento para la preparacion de compuestos de isopropi-lamina
SE7905025L (sv) Tereftalsyramonoamidderivat, forfarande for framstellning derav och antiallergiskt medel
DK128892A (da) Benzyletherderivater
SE8101592L (sv) Pyrazolopyridinoner och pyridinylnikotinater och forfarande for framstellning derav

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8205698-7

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8205698-7

Format of ref document f/p: F