ES484086A1 - Procedimiento para la preparacion de compuestos de isopropi-lamina - Google Patents
Procedimiento para la preparacion de compuestos de isopropi-laminaInfo
- Publication number
- ES484086A1 ES484086A1 ES484086A ES484086A ES484086A1 ES 484086 A1 ES484086 A1 ES 484086A1 ES 484086 A ES484086 A ES 484086A ES 484086 A ES484086 A ES 484086A ES 484086 A1 ES484086 A1 ES 484086A1
- Authority
- ES
- Spain
- Prior art keywords
- isopropyl amine
- processes
- amine compounds
- preparation
- amine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical class CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedimiento para la preparación de derivados de isopropilamina de la fórmula general I **(Fórmula)** en donde R es un radical nitrofenilo, que puede estar sustituido una o varias veces con halógenos, preferiblemente con cloro, y/o con radicales alcohilo de 1 a 4 átomos de carbono, rectos o ramificados, y/o con radicales alcoxi de 1 a 3 átomos de carbono, así como sus sales con ácidos fisiológicamente indiferentes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782839475 DE2839475A1 (de) | 1978-09-11 | 1978-09-11 | Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484086A1 true ES484086A1 (es) | 1980-05-16 |
Family
ID=6049154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES484086A Expired ES484086A1 (es) | 1978-09-11 | 1979-09-11 | Procedimiento para la preparacion de compuestos de isopropi-lamina |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4371545A (es) |
| EP (1) | EP0009168A1 (es) |
| JP (1) | JPS5555145A (es) |
| AU (1) | AU5041879A (es) |
| DE (1) | DE2839475A1 (es) |
| ES (1) | ES484086A1 (es) |
| ZA (1) | ZA794608B (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2065291A1 (es) * | 1993-07-30 | 1995-02-01 | Prodesfarma Sa | "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente" |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL301580A (es) * | 1962-12-11 | |||
| US3275629A (en) * | 1963-03-20 | 1966-09-27 | Monsanto Co | Substituted aryloxyalkylene amines |
| US3459782A (en) * | 1963-08-26 | 1969-08-05 | Boehringer Sohn Ingelheim | 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes |
| US3637852A (en) * | 1963-08-26 | 1972-01-25 | Boehringer Sohn Ingelheim | 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof |
| DE1493454C3 (de) * | 1963-08-26 | 1980-04-30 | C.H. Boehringer Sohn, 6507 Ingelheim | 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel |
| US3331850A (en) * | 1964-05-13 | 1967-07-18 | Upjohn Co | 5-(aryloxymethyl)-2-oxazolidinethiones |
| DE1593762A1 (de) * | 1967-02-06 | 1972-06-08 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen |
| DE1643262C3 (de) * | 1967-12-13 | 1975-06-26 | C.H. Boehringer Sohn, 6507 Ingelheim | i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| GB1458392A (en) * | 1973-11-09 | 1976-12-15 | Ici Ltd | Optically-active 1-aryloxy-2,3-epoxypropane derivatives |
-
1978
- 1978-09-11 DE DE19782839475 patent/DE2839475A1/de not_active Withdrawn
-
1979
- 1979-08-30 AU AU50418/79A patent/AU5041879A/en not_active Abandoned
- 1979-08-31 JP JP11049779A patent/JPS5555145A/ja active Pending
- 1979-08-31 ZA ZA00794608A patent/ZA794608B/xx unknown
- 1979-09-05 EP EP79103279A patent/EP0009168A1/de not_active Ceased
- 1979-09-11 ES ES484086A patent/ES484086A1/es not_active Expired
-
1981
- 1981-03-17 US US06/244,823 patent/US4371545A/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2065291A1 (es) * | 1993-07-30 | 1995-02-01 | Prodesfarma Sa | "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente" |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA794608B (en) | 1980-08-27 |
| DE2839475A1 (de) | 1980-03-20 |
| EP0009168A1 (de) | 1980-04-02 |
| US4371545A (en) | 1983-02-01 |
| JPS5555145A (en) | 1980-04-22 |
| AU5041879A (en) | 1980-03-20 |
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