SE7709942L - Uracilderivat och forfarande for framstellning derav - Google Patents

Uracilderivat och forfarande for framstellning derav

Info

Publication number
SE7709942L
SE7709942L SE7709942A SE7709942A SE7709942L SE 7709942 L SE7709942 L SE 7709942L SE 7709942 A SE7709942 A SE 7709942A SE 7709942 A SE7709942 A SE 7709942A SE 7709942 L SE7709942 L SE 7709942L
Authority
SE
Sweden
Prior art keywords
uracile
procedures
derivatives
manufacture
uracile derivatives
Prior art date
Application number
SE7709942A
Other languages
English (en)
Other versions
SE438856B (sv
Inventor
S Ozaki
Y Ike
K Ishikawa
H Tamura
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of SE7709942L publication Critical patent/SE7709942L/sv
Publication of SE438856B publication Critical patent/SE438856B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7709942A 1976-09-06 1977-09-05 Analogiforfarande for framstellning av 1-acyloximetyl-3-fluoruracilderivat SE438856B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10571476A JPS5331676A (en) 1976-09-06 1976-09-06 Uracil derivatives and their preparation

Publications (2)

Publication Number Publication Date
SE7709942L true SE7709942L (sv) 1978-03-07
SE438856B SE438856B (sv) 1985-05-13

Family

ID=14414993

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7709942A SE438856B (sv) 1976-09-06 1977-09-05 Analogiforfarande for framstellning av 1-acyloximetyl-3-fluoruracilderivat

Country Status (16)

Country Link
US (1) US4267326A (sv)
JP (1) JPS5331676A (sv)
AU (1) AU513153B2 (sv)
CH (1) CH634567A5 (sv)
DE (1) DE2739912A1 (sv)
DK (1) DK142413B (sv)
FI (1) FI62071C (sv)
FR (1) FR2363563A1 (sv)
GB (1) GB1543467A (sv)
HU (1) HU177482B (sv)
NL (1) NL7709808A (sv)
PH (1) PH14000A (sv)
PL (1) PL108914B1 (sv)
SE (1) SE438856B (sv)
SU (1) SU795468A3 (sv)
ZA (1) ZA775361B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5379879A (en) * 1976-12-23 1978-07-14 Mitsui Toatsu Chem Inc 1,3-substituted-5-fluorouracils and process for their preparation
JPS54122281A (en) * 1978-03-13 1979-09-21 Mitsui Toatsu Chem Inc 5-fluorouracil derivative and its preparation
JPS5668674A (en) * 1979-11-08 1981-06-09 Shionogi & Co Ltd 5-fluorouracil derivative
JPS5724369A (en) * 1980-07-19 1982-02-08 Tokyo Kinzoku Kogyo Kk Pyrimidine derivative and its preparation
JPS5738774A (en) * 1980-08-19 1982-03-03 Chugai Pharmaceut Co Ltd Uracil derivative and its preparation
DE3480706D1 (de) * 1983-10-20 1990-01-18 Terumo Corp 5-fluoruracilabkoemmlinge sowie medizinische zusammensetzungen die diese enthalten.
DK197486A (da) * 1986-04-30 1987-10-31 Ferring Farma Lab 5-fluoruracilprodug
US6051576A (en) * 1994-01-28 2000-04-18 University Of Kentucky Research Foundation Means to achieve sustained release of synergistic drugs by conjugation
HRP20171415T4 (hr) 2009-06-25 2023-03-03 Alkermes Pharma Ireland Limited Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja
WO2010151711A1 (en) 2009-06-25 2010-12-29 Alkermes, Inc. Prodrugs of nh-acidic compounds
CA2885196C (en) 2012-09-19 2021-06-22 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
CN110368360A (zh) 2014-03-20 2019-10-25 奥克梅斯制药爱尔兰有限公司 具有增加的注射速度的阿立哌唑制剂
CN112423754A (zh) 2018-03-05 2021-02-26 奥克梅斯制药爱尔兰有限公司 阿立哌唑的给药策略
CN109761915B (zh) * 2019-03-05 2021-12-21 沈阳药科大学 靶向mct1转运体的5-氟尿嘧啶成酯前药

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324952B2 (sv) * 1973-11-28 1978-07-24
JPS603071B2 (ja) * 1975-02-17 1985-01-25 三井製薬工業株式会社 1−(α−アシロキシアルキル)−5−フルオロウラシル類の製造方法

Also Published As

Publication number Publication date
US4267326A (en) 1981-05-12
SU795468A3 (ru) 1981-01-07
HU177482B (en) 1981-10-28
PL200685A1 (pl) 1978-10-09
NL7709808A (nl) 1978-03-08
AU513153B2 (en) 1980-11-20
DE2739912A1 (de) 1978-03-09
FI62071B (fi) 1982-07-30
FI772594A (fi) 1978-03-07
GB1543467A (en) 1979-04-04
FR2363563A1 (fr) 1978-03-31
PH14000A (en) 1980-11-28
ZA775361B (en) 1978-07-26
FR2363563B1 (sv) 1980-06-20
JPS6114148B2 (sv) 1986-04-17
DK394477A (sv) 1978-03-07
CH634567A5 (de) 1983-02-15
FI62071C (fi) 1982-11-10
AU2857177A (en) 1979-03-15
PL108914B1 (en) 1980-05-31
DK142413B (da) 1980-10-27
JPS5331676A (en) 1978-03-25
SE438856B (sv) 1985-05-13
DK142413C (sv) 1981-03-23

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