PL200685A1 - Sposob wytwarzania nowych pochodnych uracylu - Google Patents

Sposob wytwarzania nowych pochodnych uracylu

Info

Publication number
PL200685A1
PL200685A1 PL20068577A PL20068577A PL200685A1 PL 200685 A1 PL200685 A1 PL 200685A1 PL 20068577 A PL20068577 A PL 20068577A PL 20068577 A PL20068577 A PL 20068577A PL 200685 A1 PL200685 A1 PL 200685A1
Authority
PL
Poland
Prior art keywords
making new
uracyl
derivatives
uracyl derivatives
making
Prior art date
Application number
PL20068577A
Other languages
English (en)
Other versions
PL108914B1 (en
Inventor
Shoichiro Ozaki
Yoshimasa Ike
Katsutoshi Ishikowa
Haruki Tamura
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of PL200685A1 publication Critical patent/PL200685A1/pl
Publication of PL108914B1 publication Critical patent/PL108914B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL1977200685A 1976-09-06 1977-09-06 Method of producing new derivatives of uracil PL108914B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10571476A JPS5331676A (en) 1976-09-06 1976-09-06 Uracil derivatives and their preparation

Publications (2)

Publication Number Publication Date
PL200685A1 true PL200685A1 (pl) 1978-10-09
PL108914B1 PL108914B1 (en) 1980-05-31

Family

ID=14414993

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1977200685A PL108914B1 (en) 1976-09-06 1977-09-06 Method of producing new derivatives of uracil

Country Status (16)

Country Link
US (1) US4267326A (pl)
JP (1) JPS5331676A (pl)
AU (1) AU513153B2 (pl)
CH (1) CH634567A5 (pl)
DE (1) DE2739912A1 (pl)
DK (1) DK142413B (pl)
FI (1) FI62071C (pl)
FR (1) FR2363563A1 (pl)
GB (1) GB1543467A (pl)
HU (1) HU177482B (pl)
NL (1) NL7709808A (pl)
PH (1) PH14000A (pl)
PL (1) PL108914B1 (pl)
SE (1) SE438856B (pl)
SU (1) SU795468A3 (pl)
ZA (1) ZA775361B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5379879A (en) * 1976-12-23 1978-07-14 Mitsui Toatsu Chem Inc 1,3-substituted-5-fluorouracils and process for their preparation
JPS54122281A (en) * 1978-03-13 1979-09-21 Mitsui Toatsu Chem Inc 5-fluorouracil derivative and its preparation
JPS5668674A (en) * 1979-11-08 1981-06-09 Shionogi & Co Ltd 5-fluorouracil derivative
JPS5724369A (en) * 1980-07-19 1982-02-08 Tokyo Kinzoku Kogyo Kk Pyrimidine derivative and its preparation
JPS5738774A (en) * 1980-08-19 1982-03-03 Chugai Pharmaceut Co Ltd Uracil derivative and its preparation
EP0162924B1 (en) * 1983-10-20 1989-12-13 Terumo Kabushiki Kaisha 5-fluorouracil derivatives and medicinal preparation containing same
DK197486A (da) * 1986-04-30 1987-10-31 Ferring Farma Lab 5-fluoruracilprodug
US6051576A (en) * 1994-01-28 2000-04-18 University Of Kentucky Research Foundation Means to achieve sustained release of synergistic drugs by conjugation
JP5732453B2 (ja) 2009-06-25 2015-06-10 アルカーメス ファーマ アイルランド リミテッド Nh酸性化合物のプロドラッグ
US8431576B2 (en) 2009-06-25 2013-04-30 Alkermes Pharma Ireland Limited Heterocyclic compounds for the treatment of neurological and psychological disorders
NZ730571A (en) 2012-09-19 2018-12-21 Alkermes Pharma Ireland Ltd Pharmaceutical compositions having improved storage stability
EP3119399A4 (en) 2014-03-20 2017-09-27 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
US11273158B2 (en) 2018-03-05 2022-03-15 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
CN109761915B (zh) * 2019-03-05 2021-12-21 沈阳药科大学 靶向mct1转运体的5-氟尿嘧啶成酯前药

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324952B2 (pl) * 1973-11-28 1978-07-24
JPS603071B2 (ja) * 1975-02-17 1985-01-25 三井製薬工業株式会社 1−(α−アシロキシアルキル)−5−フルオロウラシル類の製造方法

Also Published As

Publication number Publication date
FI62071B (fi) 1982-07-30
FR2363563A1 (fr) 1978-03-31
FI62071C (fi) 1982-11-10
PL108914B1 (en) 1980-05-31
SE438856B (sv) 1985-05-13
SU795468A3 (ru) 1981-01-07
PH14000A (en) 1980-11-28
GB1543467A (en) 1979-04-04
AU513153B2 (en) 1980-11-20
DK142413B (da) 1980-10-27
DK142413C (pl) 1981-03-23
FI772594A (fi) 1978-03-07
ZA775361B (en) 1978-07-26
US4267326A (en) 1981-05-12
HU177482B (en) 1981-10-28
JPS5331676A (en) 1978-03-25
NL7709808A (nl) 1978-03-08
DK394477A (pl) 1978-03-07
DE2739912A1 (de) 1978-03-09
JPS6114148B2 (pl) 1986-04-17
SE7709942L (sv) 1978-03-07
FR2363563B1 (pl) 1980-06-20
CH634567A5 (de) 1983-02-15
AU2857177A (en) 1979-03-15

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