DE3480706D1 - 5-fluoruracilabkoemmlinge sowie medizinische zusammensetzungen die diese enthalten. - Google Patents

5-fluoruracilabkoemmlinge sowie medizinische zusammensetzungen die diese enthalten.

Info

Publication number
DE3480706D1
DE3480706D1 DE8484903816T DE3480706T DE3480706D1 DE 3480706 D1 DE3480706 D1 DE 3480706D1 DE 8484903816 T DE8484903816 T DE 8484903816T DE 3480706 T DE3480706 T DE 3480706T DE 3480706 D1 DE3480706 D1 DE 3480706D1
Authority
DE
Germany
Prior art keywords
fluoruracilabred
combinations
compositions containing
medical compositions
medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484903816T
Other languages
English (en)
Inventor
Toshio Wakabayashi
Keiko Takahashi
Hajime Katayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58196646A external-priority patent/JPS6087272A/ja
Priority claimed from JP59095725A external-priority patent/JPS60239472A/ja
Application filed by Terumo Corp filed Critical Terumo Corp
Application granted granted Critical
Publication of DE3480706D1 publication Critical patent/DE3480706D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8484903816T 1983-10-20 1984-10-19 5-fluoruracilabkoemmlinge sowie medizinische zusammensetzungen die diese enthalten. Expired - Fee Related DE3480706D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP58196646A JPS6087272A (ja) 1983-10-20 1983-10-20 ５―フルオロウラシル誘導体を有効成分とする血小板凝集抑制剤
JP59095725A JPS60239472A (ja) 1984-05-15 1984-05-15 ５−フルオロウラシル誘導体およびこれを有効成分として含有する医薬製剤
PCT/JP1984/000499 WO1985001729A1 (en) 1983-10-20 1984-10-19 5-fluorouracil derivatives and medicinal preparation containing same

Publications (1)

Publication Number Publication Date
DE3480706D1 true DE3480706D1 (de) 1990-01-18

Family

ID=26436918

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484903816T Expired - Fee Related DE3480706D1 (de) 1983-10-20 1984-10-19 5-fluoruracilabkoemmlinge sowie medizinische zusammensetzungen die diese enthalten.

Country Status (4)

Country Link
US (1) US4704393A (de)
EP (1) EP0162924B1 (de)
DE (1) DE3480706D1 (de)
WO (1) WO1985001729A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62174060A (ja) * 1985-10-11 1987-07-30 Terumo Corp ５−フルオロウラシル誘導体およびこれを含有する医薬製剤
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
JP4634694B2 (ja) * 2001-03-23 2011-02-16 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪アルコール薬物複合体
US8552054B2 (en) * 2001-03-23 2013-10-08 Luitpold Pharmaceuticals, Inc. Fatty amine drug conjugates
CA2937222C (en) * 2009-06-25 2019-06-04 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS603071B2 (ja) * 1975-02-17 1985-01-25 三井製薬工業株式会社 １−（α−アシロキシアルキル）−５−フルオロウラシル類の製造方法
JPS5331676A (en) * 1976-09-06 1978-03-25 Mitsui Toatsu Chem Inc Uracil derivatives and their preparation
JPS5877871A (ja) * 1981-10-30 1983-05-11 Kuraray Co Ltd ５−フルオロウラシルのカルボン酸誘導体
JPS5967275A (ja) * 1982-10-08 1984-04-16 Terumo Corp ５−フルオロウラシル誘導体およびその製法

Also Published As

Publication number Publication date
EP0162924A1 (de) 1985-12-04
EP0162924B1 (de) 1989-12-13
US4704393A (en) 1987-11-03
WO1985001729A1 (en) 1985-04-25
EP0162924A4 (de) 1987-02-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee