SE7701045L - Prostansyraderivat - Google Patents
ProstansyraderivatInfo
- Publication number
- SE7701045L SE7701045L SE7701045A SE7701045A SE7701045L SE 7701045 L SE7701045 L SE 7701045L SE 7701045 A SE7701045 A SE 7701045A SE 7701045 A SE7701045 A SE 7701045A SE 7701045 L SE7701045 L SE 7701045L
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- image
- iodine
- compounds
- bound
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000003180 prostaglandins Chemical class 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- 230000004520 agglutination Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000005695 dehalogenation reaction Methods 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000026045 iodination Effects 0.000 abstract 1
- 238000006192 iodination reaction Methods 0.000 abstract 1
- 150000002496 iodine Chemical class 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 150000002497 iodine compounds Chemical class 0.000 abstract 1
- -1 keto compound Chemical class 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000017105 transposition Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65511076A | 1976-02-04 | 1976-02-04 | |
| US71696976A | 1976-08-23 | 1976-08-23 | |
| US71696076A | 1976-08-23 | 1976-08-23 | |
| US71677176A | 1976-08-23 | 1976-08-23 | |
| US71677076A | 1976-08-23 | 1976-08-23 | |
| US71697276A | 1976-08-23 | 1976-08-23 | |
| US72554876A | 1976-09-22 | 1976-09-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7701045L true SE7701045L (sv) | 1977-08-05 |
| SE435281B SE435281B (sv) | 1984-09-17 |
Family
ID=27569874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7701045A SE435281B (sv) | 1976-02-04 | 1977-02-01 | Forfarande for framstellning av prostaglandinderivat |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5936911B2 (sv) |
| BE (1) | BE851122A (sv) |
| CA (3) | CA1160627A (sv) |
| CH (2) | CH632245A5 (sv) |
| DE (1) | DE2702553C2 (sv) |
| FR (3) | FR2359125B1 (sv) |
| GB (1) | GB1554044A (sv) |
| HK (1) | HK9385A (sv) |
| IL (1) | IL51189A (sv) |
| MX (1) | MX4811E (sv) |
| NL (2) | NL185515C (sv) |
| NZ (1) | NZ183050A (sv) |
| SE (1) | SE435281B (sv) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1583961A (en) * | 1976-05-11 | 1981-02-04 | Wellcome Found | Prostacyclin and derivatives thereof |
| JPS537665A (en) * | 1976-05-11 | 1978-01-24 | Wellcome Found | Novel ether* its preparation and its use |
| GB1595056A (en) * | 1976-10-12 | 1981-08-05 | Wellcome Found | Pharmaceutical combination |
| AU511711B2 (en) * | 1976-12-30 | 1980-09-04 | Upjohn Company, The | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
| FI71138C (fi) * | 1976-12-31 | 1986-11-24 | Erba Farmitalia | Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner |
| AU524786B2 (en) * | 1977-03-07 | 1982-10-07 | The Upjohn Company | Prostacyclins |
| JPS53136513A (en) * | 1977-05-06 | 1978-11-29 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin-x-related compounds |
| JPS6022710B2 (ja) * | 1977-09-16 | 1985-06-03 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
| DE2743283A1 (de) * | 1977-09-27 | 1979-04-05 | Hoechst Ag | Neue prostacyclin-analoga |
| IT1088036B (it) | 1977-11-25 | 1985-06-04 | Erba Carlo Spa | 15-epi-prostaciclina e prostaciclina analoghi |
| US4705806A (en) * | 1978-02-13 | 1987-11-10 | Morton Jr Douglas R | Prostacyclin analogs |
| DE2811950A1 (de) * | 1978-03-18 | 1979-12-13 | Hoechst Ag | Neue analoga von prostacyclin |
| IT1099575B (it) * | 1978-07-20 | 1985-09-18 | Erba Carlo Spa | 20-metil-13,14-deidro-pgi2' suoi sali e suoi 16s- e 16r-metil derivati |
| DE2834248A1 (de) * | 1978-08-04 | 1980-02-28 | Hoechst Ag | Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe |
| US4180657A (en) * | 1978-08-14 | 1979-12-25 | The Upjohn Company | Acyl-substituted phenyl esters of prostacyclin-type compounds |
| JPS56122372A (en) * | 1980-03-03 | 1981-09-25 | Toray Ind Inc | Prostaglandin i2 derivative |
| DE3029984C2 (de) * | 1980-08-08 | 1983-12-15 | Grünenthal GmbH, 5190 Stolberg | 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel |
| CH648556A5 (de) * | 1981-03-11 | 1985-03-29 | Hoffmann La Roche | Fluorprostacycline. |
| JPS595155A (ja) * | 1982-06-30 | 1984-01-12 | Ono Pharmaceut Co Ltd | プロスタグランジンｄ類似化合物 |
| CA1324129C (en) * | 1987-04-30 | 1993-11-09 | Ryuzo Ueno | Prostaglandins of the f series |
| US5221763A (en) * | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| US5591887A (en) * | 1987-04-30 | 1997-01-07 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| AU619543B2 (en) * | 1988-05-11 | 1992-01-30 | Sucampo Ag | Use of 15-ketoprostaglandin e or f compounds for uterine contraction |
| US5185374A (en) * | 1988-05-11 | 1993-02-09 | K.K. Ueno Seiyaku Oyo Kenkyujo | Use of 15-ketoprostaglandin E or F compounds for uterine contraction |
| MX2012000889A (es) | 2009-07-28 | 2012-02-13 | Ono Pharmaceutical Co | Compuesto biciclico y uso del mismo para propositos medicos. |
| US9029574B2 (en) | 2011-01-27 | 2015-05-12 | Ono Pharmaceutical Co., Ltd. | Bicyclic compound and use thereof for medical purposes |
| CN116143742A (zh) * | 2023-02-27 | 2023-05-23 | 广州楷石生物科技有限公司 | 依前列醇一氧化氮供体药物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2351112A1 (fr) * | 1975-10-21 | 1977-12-09 | Wellcome Found | Derive de prostaglandine et medicament contenant ce derive |
| JPS537665A (en) * | 1976-05-11 | 1978-01-24 | Wellcome Found | Novel ether* its preparation and its use |
| MX4813E (es) * | 1976-06-01 | 1982-10-19 | Upjohn Co | Procedimiento para preparar analogos de prostaglandinas |
| AU511711B2 (en) * | 1976-12-30 | 1980-09-04 | Upjohn Company, The | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
-
1976
- 1976-12-30 IL IL51189A patent/IL51189A/xx unknown
-
1977
- 1977-01-11 NZ NZ183050A patent/NZ183050A/xx unknown
- 1977-01-22 DE DE2702553A patent/DE2702553C2/de not_active Expired
- 1977-01-25 CA CA000270416A patent/CA1160627A/en not_active Expired
- 1977-01-27 GB GB3314/77A patent/GB1554044A/en not_active Expired
- 1977-01-28 NL NLAANVRAGE7700896,A patent/NL185515C/xx not_active IP Right Cessation
- 1977-02-01 SE SE7701045A patent/SE435281B/sv not_active IP Right Cessation
- 1977-02-03 JP JP52010332A patent/JPS5936911B2/ja not_active Expired
- 1977-02-03 FR FR7703076A patent/FR2359125B1/fr not_active Expired
- 1977-02-04 BE BE174693A patent/BE851122A/xx not_active IP Right Cessation
- 1977-02-04 CH CH141677A patent/CH632245A5/de not_active IP Right Cessation
- 1977-10-26 FR FR7732283A patent/FR2362834A1/fr active Granted
- 1977-10-26 FR FR7732282A patent/FR2362833A1/fr active Granted
- 1977-11-04 MX MX775413U patent/MX4811E/es unknown
-
1978
- 1978-10-26 CA CA000349868A patent/CA1160628A/en not_active Expired
- 1978-10-26 CA CA000349870A patent/CA1179335A/en not_active Expired
-
1982
- 1982-04-02 CH CH206082A patent/CH637949A5/de not_active IP Right Cessation
-
1983
- 1983-07-01 NL NL8300921A patent/NL8300921A/nl not_active Application Discontinuation
-
1985
- 1985-01-31 HK HK93/85A patent/HK9385A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL185515C (nl) | 1990-05-01 |
| NL8300921A (nl) | 1983-07-01 |
| CA1160628A (en) | 1984-01-17 |
| NZ183050A (en) | 1979-06-08 |
| DE2702553A1 (de) | 1977-08-18 |
| NL7700896A (nl) | 1977-08-08 |
| FR2362833B1 (sv) | 1980-08-08 |
| MX4811E (es) | 1982-10-19 |
| GB1554044A (en) | 1979-10-17 |
| DE2702553C2 (de) | 1986-02-20 |
| CA1179335A (en) | 1984-12-11 |
| JPS5295644A (en) | 1977-08-11 |
| FR2359125B1 (fr) | 1985-11-15 |
| FR2362834B1 (sv) | 1980-08-08 |
| HK9385A (en) | 1985-02-08 |
| FR2362833A1 (fr) | 1978-03-24 |
| IL51189A (en) | 1985-08-30 |
| NL185515B (nl) | 1989-12-01 |
| CA1160627A (en) | 1984-01-17 |
| FR2362834A1 (fr) | 1978-03-24 |
| FR2359125A1 (fr) | 1978-02-17 |
| IL51189A0 (en) | 1977-02-28 |
| CH637949A5 (en) | 1983-08-31 |
| CH632245A5 (en) | 1982-09-30 |
| JPS5936911B2 (ja) | 1984-09-06 |
| BE851122A (fr) | 1977-08-04 |
| SE435281B (sv) | 1984-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7701045-2 Effective date: 19880125 Format of ref document f/p: F |