ATE13523T1 - 11-deoxoglycyrrhetinsaeurehydrogenmaleinat, verfahren zu dessen herstellung und seine verwendung als medikament. - Google Patents
11-deoxoglycyrrhetinsaeurehydrogenmaleinat, verfahren zu dessen herstellung und seine verwendung als medikament.Info
- Publication number
- ATE13523T1 ATE13523T1 AT82105994T AT82105994T ATE13523T1 AT E13523 T1 ATE13523 T1 AT E13523T1 AT 82105994 T AT82105994 T AT 82105994T AT 82105994 T AT82105994 T AT 82105994T AT E13523 T1 ATE13523 T1 AT E13523T1
- Authority
- AT
- Austria
- Prior art keywords
- acid hydrogen
- deoxoglycyrrhetin
- medication
- preparation
- hydrogen maleinate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/593—Dicarboxylic acid esters having only one carbon-to-carbon double bond
- C07C69/60—Maleic acid esters; Fumaric acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56104406A JPS588044A (ja) | 1981-07-06 | 1981-07-06 | 11−デオキソグリチルレチン酸水素マレ−ト及びそれを有効成分とする医薬 |
EP82105994A EP0069380B1 (de) | 1981-07-06 | 1982-07-05 | 11-Deoxoglycyrrhetinsäurehydrogenmaleinat, Verfahren zu dessen Herstellung und seine Verwendung als Medikament |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE13523T1 true ATE13523T1 (de) | 1985-06-15 |
Family
ID=14379827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT82105994T ATE13523T1 (de) | 1981-07-06 | 1982-07-05 | 11-deoxoglycyrrhetinsaeurehydrogenmaleinat, verfahren zu dessen herstellung und seine verwendung als medikament. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4448788A (de) |
EP (1) | EP0069380B1 (de) |
JP (1) | JPS588044A (de) |
AT (1) | ATE13523T1 (de) |
DE (1) | DE3263882D1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU553789B2 (en) * | 1982-06-30 | 1986-07-24 | Biorex Laboratories Ltd. | Glycyrrhetinic acid derivatives in cream compositions |
IT1215626B (it) * | 1982-07-26 | 1990-02-22 | Isf Spa | Derivato dell'acido ursolico farmacologicamente attivo. |
GB2140809A (en) * | 1983-06-01 | 1984-12-05 | Biorex Laboratories Ltd | New derivatives of glycyrrhetinic acid |
JPS6058973A (ja) * | 1983-09-13 | 1985-04-05 | Mitsubishi Yuka Yakuhin Kk | γ−プチロラクトン誘導体及びそれを有効成分とする免疫調節剤 |
JPS63135351A (ja) * | 1986-11-28 | 1988-06-07 | Sanwa Kagaku Kenkyusho Co Ltd | グリチルレチン酸誘導体、その製法及び該化合物を有効成分とする抗潰瘍剤 |
US4987151A (en) * | 1989-06-19 | 1991-01-22 | The Trustees Of Columbia University In The City Of New York | Triterpene derivatives cholesterol acyltransferase inhibitors and methods of using same |
US5519008A (en) * | 1992-09-10 | 1996-05-21 | Glycomed Incorporated | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin) |
US5527890A (en) * | 1993-04-16 | 1996-06-18 | Glycomed Incorporated | Derivatives of triterpenoid acids and uses thereof |
GB0105772D0 (en) * | 2001-03-08 | 2001-04-25 | Sterix Ltd | Use |
GB0604899D0 (en) * | 2006-03-10 | 2006-04-19 | York Pharma Plc | Derivatives of 18-glycyrrhetinic acid |
CN101899081B (zh) * | 2009-05-31 | 2012-09-05 | 江苏正大天晴药业股份有限公司 | 甘草次酸酯类衍生物合成方法以及脱氧甘草次酸酯化合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1051001B (it) * | 1971-08-06 | 1981-04-21 | Isf Spa | Processo per la preparazione dell acido 3 o beta carbossipropionil ibbeta glicirretico |
GB1435622A (en) * | 1973-11-07 | 1976-05-12 | Biorex Laboratories Ltd | Erythrodiol derivatives |
GB1475075A (en) * | 1974-09-11 | 1977-06-01 | Biorex Laboratories Ltd | Derivatives of glycyrrhetinic and oleanolic acids |
GB1476053A (en) * | 1975-02-07 | 1977-06-10 | Biorex Laboratories Ltd | Glycyrrhetinic acid derivatives |
-
1981
- 1981-07-06 JP JP56104406A patent/JPS588044A/ja active Granted
-
1982
- 1982-07-01 US US06/394,114 patent/US4448788A/en not_active Expired - Fee Related
- 1982-07-05 AT AT82105994T patent/ATE13523T1/de not_active IP Right Cessation
- 1982-07-05 EP EP82105994A patent/EP0069380B1/de not_active Expired
- 1982-07-05 DE DE8282105994T patent/DE3263882D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US4448788A (en) | 1984-05-15 |
EP0069380B1 (de) | 1985-05-29 |
EP0069380A1 (de) | 1983-01-12 |
JPH0148254B2 (de) | 1989-10-18 |
DE3263882D1 (en) | 1985-07-04 |
JPS588044A (ja) | 1983-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |