BE851122A - Nouveaux derives de prostaglandine - Google Patents

Nouveaux derives de prostaglandine

Info

Publication number
BE851122A
BE851122A BE174693A BE174693A BE851122A BE 851122 A BE851122 A BE 851122A BE 174693 A BE174693 A BE 174693A BE 174693 A BE174693 A BE 174693A BE 851122 A BE851122 A BE 851122A
Authority
BE
Belgium
Prior art keywords
prostaglandin derivatives
new prostaglandin
new
derivatives
prostaglandin
Prior art date
Application number
BE174693A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE851122A publication Critical patent/BE851122A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
BE174693A 1976-02-04 1977-02-04 Nouveaux derives de prostaglandine BE851122A (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US65511076A 1976-02-04 1976-02-04
US71677176A 1976-08-23 1976-08-23
US71697276A 1976-08-23 1976-08-23
US71677076A 1976-08-23 1976-08-23
US71696976A 1976-08-23 1976-08-23
US71696076A 1976-08-23 1976-08-23
US72554876A 1976-09-22 1976-09-22

Publications (1)

Publication Number Publication Date
BE851122A true BE851122A (fr) 1977-08-04

Family

ID=27569874

Family Applications (1)

Application Number Title Priority Date Filing Date
BE174693A BE851122A (fr) 1976-02-04 1977-02-04 Nouveaux derives de prostaglandine

Country Status (13)

Country Link
JP (1) JPS5936911B2 (fr)
BE (1) BE851122A (fr)
CA (3) CA1160627A (fr)
CH (2) CH632245A5 (fr)
DE (1) DE2702553C2 (fr)
FR (3) FR2359125B1 (fr)
GB (1) GB1554044A (fr)
HK (1) HK9385A (fr)
IL (1) IL51189A (fr)
MX (1) MX4811E (fr)
NL (2) NL185515C (fr)
NZ (1) NZ183050A (fr)
SE (1) SE435281B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009869A3 (fr) * 1978-08-14 1980-06-25 The Upjohn Company Esters de type prostaglandine
US4211782A (en) * 1976-10-12 1980-07-08 Salvador Moncada Pharmaceutical combination
US4285966A (en) 1977-11-25 1981-08-25 Farmitalia Carlo Erba, S.P.A. Certain 15-epi-prostacyclins

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
JPS6022710B2 (ja) * 1977-09-16 1985-06-03 小野薬品工業株式会社 プロスタグランジン類似化合物
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
US4705806A (en) * 1978-02-13 1987-11-10 Morton Jr Douglas R Prostacyclin analogs
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
IT1099575B (it) * 1978-07-20 1985-09-18 Erba Carlo Spa 20-metil-13,14-deidro-pgi2' suoi sali e suoi 16s- e 16r-metil derivati
DE2834248A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe
JPS56122372A (en) * 1980-03-03 1981-09-25 Toray Ind Inc Prostaglandin i2 derivative
DE3029984C2 (de) * 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS595155A (ja) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd プロスタグランジンｄ類似化合物
CA1324129C (fr) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandines de la serie f
US5221763A (en) * 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5591887A (en) * 1987-04-30 1997-01-07 R-Tech Ueno, Ltd. Prostaglandins of the F series
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
US5185374A (en) * 1988-05-11 1993-02-09 K.K. Ueno Seiyaku Oyo Kenkyujo Use of 15-ketoprostaglandin E or F compounds for uterine contraction
NZ597626A (en) 2009-07-28 2013-03-28 Ono Pharmaceutical Co Bicyclic compound and use thereof for medical purposes
WO2012102357A1 (fr) 2011-01-27 2012-08-02 小野薬品工業株式会社 Composé bicyclique et utilisation associée à des fins médicales
CN116143742A (zh) * 2023-02-27 2023-05-23 广州楷石生物科技有限公司 依前列醇一氧化氮供体药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (fr) * 1975-10-21 1977-12-09 Wellcome Found Derive de prostaglandine et medicament contenant ce derive
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
MX4813E (es) * 1976-06-01 1982-10-19 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211782A (en) * 1976-10-12 1980-07-08 Salvador Moncada Pharmaceutical combination
US4285966A (en) 1977-11-25 1981-08-25 Farmitalia Carlo Erba, S.P.A. Certain 15-epi-prostacyclins
EP0009869A3 (fr) * 1978-08-14 1980-06-25 The Upjohn Company Esters de type prostaglandine
EP0038614A3 (fr) * 1978-08-14 1981-11-11 The Upjohn Company Esters de 5- et 6-oxo-prostaglandines

Also Published As

Publication number Publication date
GB1554044A (en) 1979-10-17
NL185515B (nl) 1989-12-01
FR2359125A1 (fr) 1978-02-17
CH637949A5 (en) 1983-08-31
JPS5295644A (en) 1977-08-11
CA1160628A (fr) 1984-01-17
CA1179335A (fr) 1984-12-11
FR2362833B1 (fr) 1980-08-08
JPS5936911B2 (ja) 1984-09-06
HK9385A (en) 1985-02-08
SE7701045L (sv) 1977-08-05
CH632245A5 (en) 1982-09-30
DE2702553C2 (de) 1986-02-20
IL51189A0 (en) 1977-02-28
SE435281B (sv) 1984-09-17
CA1160627A (fr) 1984-01-17
FR2359125B1 (fr) 1985-11-15
NL185515C (nl) 1990-05-01
FR2362834B1 (fr) 1980-08-08
DE2702553A1 (de) 1977-08-18
NZ183050A (en) 1979-06-08
IL51189A (en) 1985-08-30
FR2362834A1 (fr) 1978-03-24
NL7700896A (nl) 1977-08-08
FR2362833A1 (fr) 1978-03-24
NL8300921A (nl) 1983-07-01
MX4811E (es) 1982-10-19

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: THE UPJOHN CY

Effective date: 19970204