SE435281B - Forfarande for framstellning av prostaglandinderivat - Google Patents

Forfarande for framstellning av prostaglandinderivat

Info

Publication number
SE435281B
SE435281B SE7701045A SE7701045A SE435281B SE 435281 B SE435281 B SE 435281B SE 7701045 A SE7701045 A SE 7701045A SE 7701045 A SE7701045 A SE 7701045A SE 435281 B SE435281 B SE 435281B
Authority
SE
Sweden
Prior art keywords
prostagland
ingredients
procedure
preparation
prostagland ingredients
Prior art date
Application number
SE7701045A
Other languages
English (en)
Other versions
SE7701045L (sv
Inventor
U F Axen
F H Lincoln
R A Johnson
R C Kelly
J E Pike
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE7701045L publication Critical patent/SE7701045L/sv
Publication of SE435281B publication Critical patent/SE435281B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
SE7701045A 1976-02-04 1977-02-01 Forfarande for framstellning av prostaglandinderivat SE435281B (sv)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US65511076A 1976-02-04 1976-02-04
US71677176A 1976-08-23 1976-08-23
US71696976A 1976-08-23 1976-08-23
US71697276A 1976-08-23 1976-08-23
US71696076A 1976-08-23 1976-08-23
US71677076A 1976-08-23 1976-08-23
US72554876A 1976-09-22 1976-09-22

Publications (2)

Publication Number Publication Date
SE7701045L SE7701045L (sv) 1977-08-05
SE435281B true SE435281B (sv) 1984-09-17

Family

ID=27569874

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7701045A SE435281B (sv) 1976-02-04 1977-02-01 Forfarande for framstellning av prostaglandinderivat

Country Status (13)

Country Link
JP (1) JPS5936911B2 (sv)
BE (1) BE851122A (sv)
CA (3) CA1160627A (sv)
CH (2) CH632245A5 (sv)
DE (1) DE2702553C2 (sv)
FR (3) FR2359125B1 (sv)
GB (1) GB1554044A (sv)
HK (1) HK9385A (sv)
IL (1) IL51189A (sv)
MX (1) MX4811E (sv)
NL (2) NL185515C (sv)
NZ (1) NZ183050A (sv)
SE (1) SE435281B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2720998A1 (de) * 1976-05-11 1977-11-24 Wellcome Found Cyclische aether, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
JPS6022710B2 (ja) * 1977-09-16 1985-06-03 小野薬品工業株式会社 プロスタグランジン類似化合物
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
IT1088036B (it) 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
US4705806A (en) * 1978-02-13 1987-11-10 Morton Jr Douglas R Prostacyclin analogs
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
IT1099575B (it) * 1978-07-20 1985-09-18 Erba Carlo Spa 20-metil-13,14-deidro-pgi2' suoi sali e suoi 16s- e 16r-metil derivati
DE2834248A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe
US4180657A (en) * 1978-08-14 1979-12-25 The Upjohn Company Acyl-substituted phenyl esters of prostacyclin-type compounds
JPS56122372A (en) * 1980-03-03 1981-09-25 Toray Ind Inc Prostaglandin i2 derivative
DE3029984C2 (de) * 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS595155A (ja) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd プロスタグランジンd類似化合物
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
US5221763A (en) * 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5591887A (en) * 1987-04-30 1997-01-07 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5185374A (en) * 1988-05-11 1993-02-09 K.K. Ueno Seiyaku Oyo Kenkyujo Use of 15-ketoprostaglandin E or F compounds for uterine contraction
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
ES2567328T3 (es) 2009-07-28 2016-04-21 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
EP2669279B1 (en) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
CN116143742A (zh) * 2023-02-27 2023-05-23 广州楷石生物科技有限公司 依前列醇一氧化氮供体药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (fr) * 1975-10-21 1977-12-09 Wellcome Found Derive de prostaglandine et medicament contenant ce derive
DE2720998A1 (de) * 1976-05-11 1977-11-24 Wellcome Found Cyclische aether, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
MX4813E (es) * 1976-06-01 1982-10-19 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues

Also Published As

Publication number Publication date
NZ183050A (en) 1979-06-08
FR2362833A1 (fr) 1978-03-24
FR2362833B1 (sv) 1980-08-08
BE851122A (fr) 1977-08-04
NL7700896A (nl) 1977-08-08
FR2362834A1 (fr) 1978-03-24
CA1179335A (en) 1984-12-11
NL8300921A (nl) 1983-07-01
CH632245A5 (en) 1982-09-30
DE2702553C2 (de) 1986-02-20
IL51189A (en) 1985-08-30
JPS5936911B2 (ja) 1984-09-06
NL185515C (nl) 1990-05-01
SE7701045L (sv) 1977-08-05
CA1160627A (en) 1984-01-17
FR2359125A1 (fr) 1978-02-17
DE2702553A1 (de) 1977-08-18
FR2359125B1 (fr) 1985-11-15
CA1160628A (en) 1984-01-17
JPS5295644A (en) 1977-08-11
IL51189A0 (en) 1977-02-28
CH637949A5 (en) 1983-08-31
GB1554044A (en) 1979-10-17
FR2362834B1 (sv) 1980-08-08
HK9385A (en) 1985-02-08
MX4811E (es) 1982-10-19
NL185515B (nl) 1989-12-01

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