SE435281B - PROCEDURE FOR PREPARATION OF PROSTAGLAND INGREDIENTS - Google Patents

PROCEDURE FOR PREPARATION OF PROSTAGLAND INGREDIENTS

Info

Publication number
SE435281B
SE435281B SE7701045A SE7701045A SE435281B SE 435281 B SE435281 B SE 435281B SE 7701045 A SE7701045 A SE 7701045A SE 7701045 A SE7701045 A SE 7701045A SE 435281 B SE435281 B SE 435281B
Authority
SE
Sweden
Prior art keywords
prostagland
ingredients
procedure
preparation
prostagland ingredients
Prior art date
Application number
SE7701045A
Other languages
Swedish (sv)
Other versions
SE7701045L (en
Inventor
U F Axen
F H Lincoln
R A Johnson
R C Kelly
J E Pike
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE7701045L publication Critical patent/SE7701045L/en
Publication of SE435281B publication Critical patent/SE435281B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
SE7701045A 1976-02-04 1977-02-01 PROCEDURE FOR PREPARATION OF PROSTAGLAND INGREDIENTS SE435281B (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US65511076A 1976-02-04 1976-02-04
US71697276A 1976-08-23 1976-08-23
US71677176A 1976-08-23 1976-08-23
US71677076A 1976-08-23 1976-08-23
US71696976A 1976-08-23 1976-08-23
US71696076A 1976-08-23 1976-08-23
US72554876A 1976-09-22 1976-09-22

Publications (2)

Publication Number Publication Date
SE7701045L SE7701045L (en) 1977-08-05
SE435281B true SE435281B (en) 1984-09-17

Family

ID=27569874

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7701045A SE435281B (en) 1976-02-04 1977-02-01 PROCEDURE FOR PREPARATION OF PROSTAGLAND INGREDIENTS

Country Status (13)

Country Link
JP (1) JPS5936911B2 (en)
BE (1) BE851122A (en)
CA (3) CA1160627A (en)
CH (2) CH632245A5 (en)
DE (1) DE2702553C2 (en)
FR (3) FR2359125B1 (en)
GB (1) GB1554044A (en)
HK (1) HK9385A (en)
IL (1) IL51189A (en)
MX (1) MX4811E (en)
NL (2) NL185515C (en)
NZ (1) NZ183050A (en)
SE (1) SE435281B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
IT1079025B (en) * 1976-05-11 1985-05-08 Wellcome Found IMPROVEMENT IN THE PREPARATION OF ETERI
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
FI71138C (en) * 1976-12-31 1986-11-24 Erba Farmitalia FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ACTIVE BISYCLISKA PROSTAGLANDINER
US4178367A (en) 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
US4219647A (en) 1977-09-22 1980-08-26 Josef Fried Certain amides of prostacyclin and related compounds
JPS6022710B2 (en) * 1977-09-16 1985-06-03 小野薬品工業株式会社 Prostaglandin-like compounds
DE2743283A1 (en) * 1977-09-27 1979-04-05 Hoechst Ag NEW PROSTACYCLIN ANALOG
IT1088036B (en) 1977-11-25 1985-06-04 Erba Carlo Spa 15-EPI-PROSTACYCLINE AND ANALOG PROSTACYCLINE
US4705806A (en) * 1978-02-13 1987-11-10 Morton Jr Douglas R Prostacyclin analogs
DE2811950A1 (en) * 1978-03-18 1979-12-13 Hoechst Ag NEW PROSTACYCLIN ANALOGS
HU179001B (en) 1978-05-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 5-halo-6,9alpha-oxido-prostaglandin derivatives
IT1099575B (en) * 1978-07-20 1985-09-18 Erba Carlo Spa 20-METHYL-13,14-DEHYDRO-PGI2 'ITS SALTS AND ITS 16S- AND 16R-METHYL DERIVATIVES
DE2834248A1 (en) * 1978-08-04 1980-02-28 Hoechst Ag NEW PROSTAGLAND DERIVATIVES IN THE DELTA 2-PGF TIEF 2 AND DELTA 2-PGE TIEF 2 SERIES
US4180657A (en) * 1978-08-14 1979-12-25 The Upjohn Company Acyl-substituted phenyl esters of prostacyclin-type compounds
JPS56122372A (en) * 1980-03-03 1981-09-25 Toray Ind Inc Prostaglandin i2 derivative
DE3029984C2 (en) * 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octane derivatives and medicinal products containing them
CH651033A5 (en) * 1981-03-11 1985-08-30 Hoffmann La Roche Fluorprostacycline.
AT381309B (en) * 1982-05-27 1986-09-25 Gruenenthal Gmbh METHOD FOR PRODUCING 5Z-SHAPES OF 2,3,4-TRINOR-1,5-INTER-M-PHENYLENE-PROSTACYCLINDERIVA EN
JPS595155A (en) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd Prostaglandin d-mimic compound, its preparation and antitumor agent containing the same
US5591887A (en) * 1987-04-30 1997-01-07 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5221763A (en) * 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
US5185374A (en) * 1988-05-11 1993-02-09 K.K. Ueno Seiyaku Oyo Kenkyujo Use of 15-ketoprostaglandin E or F compounds for uterine contraction
AU2010279183B2 (en) 2009-07-28 2015-10-29 Ono Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
EP2669279B1 (en) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
CN116143742B (en) * 2023-02-27 2024-10-18 广州楷石生物科技有限公司 Epoprostenol nitric oxide donor drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (en) * 1975-10-21 1977-12-09 Wellcome Found Prostaglandin derivs.
IT1079025B (en) * 1976-05-11 1985-05-08 Wellcome Found IMPROVEMENT IN THE PREPARATION OF ETERI
MX4813E (en) * 1976-06-01 1982-10-19 Upjohn Co PROCEDURE FOR PREPARING ANALOGS OF PROSTAGLANDINAS
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues

Also Published As

Publication number Publication date
MX4811E (en) 1982-10-19
FR2362834B1 (en) 1980-08-08
NL8300921A (en) 1983-07-01
SE7701045L (en) 1977-08-05
JPS5936911B2 (en) 1984-09-06
NL7700896A (en) 1977-08-08
GB1554044A (en) 1979-10-17
HK9385A (en) 1985-02-08
IL51189A (en) 1985-08-30
CA1160628A (en) 1984-01-17
DE2702553C2 (en) 1986-02-20
BE851122A (en) 1977-08-04
FR2359125A1 (en) 1978-02-17
JPS5295644A (en) 1977-08-11
DE2702553A1 (en) 1977-08-18
NL185515C (en) 1990-05-01
FR2359125B1 (en) 1985-11-15
CA1160627A (en) 1984-01-17
CH637949A5 (en) 1983-08-31
FR2362833A1 (en) 1978-03-24
CH632245A5 (en) 1982-09-30
IL51189A0 (en) 1977-02-28
FR2362834A1 (en) 1978-03-24
NL185515B (en) 1989-12-01
CA1179335A (en) 1984-12-11
NZ183050A (en) 1979-06-08
FR2362833B1 (en) 1980-08-08

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