NL185515B - PROCESS FOR PREPARING PROSTAGLANDINE DERIVATIVES AND PROCESS FOR PREPARING A THERAPEUTIC PREPARATION CONTAINING THE PROSTAGLANDINE DERIVATIVE. - Google Patents

PROCESS FOR PREPARING PROSTAGLANDINE DERIVATIVES AND PROCESS FOR PREPARING A THERAPEUTIC PREPARATION CONTAINING THE PROSTAGLANDINE DERIVATIVE.

Info

Publication number
NL185515B
NL185515B NLAANVRAGE7700896,A NL7700896A NL185515B NL 185515 B NL185515 B NL 185515B NL 7700896 A NL7700896 A NL 7700896A NL 185515 B NL185515 B NL 185515B
Authority
NL
Netherlands
Prior art keywords
preparing
prostaglandine
derivative
preparation containing
derivatives
Prior art date
Application number
NLAANVRAGE7700896,A
Other languages
Dutch (nl)
Other versions
NL185515C (en
NL7700896A (en
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NL7700896A publication Critical patent/NL7700896A/en
Publication of NL185515B publication Critical patent/NL185515B/en
Application granted granted Critical
Publication of NL185515C publication Critical patent/NL185515C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
NLAANVRAGE7700896,A 1976-02-04 1977-01-28 PROCESS FOR PREPARING PROSTAGLANDINE DERIVATIVES AND PROCESS FOR PREPARING A THERAPEUTIC PREPARATION CONTAINING THE PROSTAGLANDINE DERIVATIVE. NL185515C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US65511076A 1976-02-04 1976-02-04
US71677176A 1976-08-23 1976-08-23
US71677076A 1976-08-23 1976-08-23
US71696076A 1976-08-23 1976-08-23
US71696976A 1976-08-23 1976-08-23
US71697276A 1976-08-23 1976-08-23
US72554876A 1976-09-22 1976-09-22

Publications (3)

Publication Number Publication Date
NL7700896A NL7700896A (en) 1977-08-08
NL185515B true NL185515B (en) 1989-12-01
NL185515C NL185515C (en) 1990-05-01

Family

ID=27569874

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE7700896,A NL185515C (en) 1976-02-04 1977-01-28 PROCESS FOR PREPARING PROSTAGLANDINE DERIVATIVES AND PROCESS FOR PREPARING A THERAPEUTIC PREPARATION CONTAINING THE PROSTAGLANDINE DERIVATIVE.
NL8300921A NL8300921A (en) 1976-02-04 1983-07-01 PROCESS FOR PREPARING PROSTAGLANDIN DERIVATIVES.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL8300921A NL8300921A (en) 1976-02-04 1983-07-01 PROCESS FOR PREPARING PROSTAGLANDIN DERIVATIVES.

Country Status (13)

Country Link
JP (1) JPS5936911B2 (en)
BE (1) BE851122A (en)
CA (3) CA1160627A (en)
CH (2) CH632245A5 (en)
DE (1) DE2702553C2 (en)
FR (3) FR2359125B1 (en)
GB (1) GB1554044A (en)
HK (1) HK9385A (en)
IL (1) IL51189A (en)
MX (1) MX4811E (en)
NL (2) NL185515C (en)
NZ (1) NZ183050A (en)
SE (1) SE435281B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
FI71138C (en) * 1976-12-31 1986-11-24 Erba Farmitalia FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ACTIVE BISYCLISKA PROSTAGLANDINER
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
JPS6022710B2 (en) * 1977-09-16 1985-06-03 小野薬品工業株式会社 Prostaglandin-like compounds
DE2743283A1 (en) * 1977-09-27 1979-04-05 Hoechst Ag NEW PROSTACYCLIN ANALOG
IT1088036B (en) 1977-11-25 1985-06-04 Erba Carlo Spa 15-EPI-PROSTACYCLINE AND ANALOG PROSTACYCLINE
US4705806A (en) * 1978-02-13 1987-11-10 Morton Jr Douglas R Prostacyclin analogs
DE2811950A1 (en) * 1978-03-18 1979-12-13 Hoechst Ag NEW PROSTACYCLIN ANALOGS
IT1099575B (en) * 1978-07-20 1985-09-18 Erba Carlo Spa 20-METHYL-13,14-DEHYDRO-PGI2 'ITS SALTS AND ITS 16S- AND 16R-METHYL DERIVATIVES
DE2834248A1 (en) * 1978-08-04 1980-02-28 Hoechst Ag NEW PROSTAGLAND DERIVATIVES IN THE DELTA 2-PGF TIEF 2 AND DELTA 2-PGE TIEF 2 SERIES
US4180657A (en) * 1978-08-14 1979-12-25 The Upjohn Company Acyl-substituted phenyl esters of prostacyclin-type compounds
JPS56122372A (en) * 1980-03-03 1981-09-25 Toray Ind Inc Prostaglandin i2 derivative
DE3029984C2 (en) * 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octane derivatives and medicinal products containing them
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
JPS595155A (en) * 1982-06-30 1984-01-12 Ono Pharmaceut Co Ltd Prostaglandin d-mimic compound, its preparation and antitumor agent containing the same
US5221763A (en) * 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
US5591887A (en) * 1987-04-30 1997-01-07 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5185374A (en) * 1988-05-11 1993-02-09 K.K. Ueno Seiyaku Oyo Kenkyujo Use of 15-ketoprostaglandin E or F compounds for uterine contraction
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
RU2540330C2 (en) 2009-07-28 2015-02-10 Оно Фармасьютикал Ко., Лтд. Bicyclic compound and using it for medical applications
US9029574B2 (en) 2011-01-27 2015-05-12 Ono Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
CN116143742B (en) * 2023-02-27 2024-10-18 广州楷石生物科技有限公司 Epoprostenol nitric oxide donor drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (en) * 1975-10-21 1977-12-09 Wellcome Found Prostaglandin derivs.
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
MX4813E (en) * 1976-06-01 1982-10-19 Upjohn Co PROCEDURE FOR PREPARING ANALOGS OF PROSTAGLANDINAS
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues

Also Published As

Publication number Publication date
FR2359125A1 (en) 1978-02-17
FR2362833B1 (en) 1980-08-08
SE7701045L (en) 1977-08-05
BE851122A (en) 1977-08-04
HK9385A (en) 1985-02-08
FR2362834A1 (en) 1978-03-24
DE2702553A1 (en) 1977-08-18
JPS5936911B2 (en) 1984-09-06
NZ183050A (en) 1979-06-08
CH632245A5 (en) 1982-09-30
SE435281B (en) 1984-09-17
FR2359125B1 (en) 1985-11-15
CH637949A5 (en) 1983-08-31
NL185515C (en) 1990-05-01
JPS5295644A (en) 1977-08-11
NL7700896A (en) 1977-08-08
IL51189A (en) 1985-08-30
CA1160628A (en) 1984-01-17
IL51189A0 (en) 1977-02-28
NL8300921A (en) 1983-07-01
MX4811E (en) 1982-10-19
DE2702553C2 (en) 1986-02-20
CA1179335A (en) 1984-12-11
CA1160627A (en) 1984-01-17
FR2362834B1 (en) 1980-08-08
FR2362833A1 (en) 1978-03-24
GB1554044A (en) 1979-10-17

Similar Documents

Publication Publication Date Title
NL185515C (en) PROCESS FOR PREPARING PROSTAGLANDINE DERIVATIVES AND PROCESS FOR PREPARING A THERAPEUTIC PREPARATION CONTAINING THE PROSTAGLANDINE DERIVATIVE.
NL7700192A (en) METHOD OF PREPARING A SWEETMAKING PREPARATION.
NL184891C (en) METHOD FOR PREPARING ZEOLITE A.
NL184558C (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION CONTAINING A MOTHERNESS CALCALIDE; PHARMACEUTICAL OBJECT.
NL172917C (en) METHOD FOR PREPARING A MEDICINE AGAINST CANCER.
NL7702123A (en) PROCEDURES FOR PREPARING AND USING A CHINAZOLINE DERIVATIVE.
NL7714043A (en) PROCESS FOR PREPARING A PREPARATION FOR VETERINARY USE.
NL187478C (en) METHOD FOR PREPARING AMIDOXIM DERIVATIVES, AND METHOD FOR PREPARING A MEDICINAL PRODUCT
NL7605322A (en) PROCESS FOR PREPARING A THERAPEUTIC PREPARATION.
NL7704585A (en) METHOD FOR PREPARING A MEDICINAL PRODUCT.
NL187066C (en) METHOD FOR PREPARING 1,3-DIG SUBSTITUTED NITROSOURUM DERIVATIVES; METHOD FOR PREPARING A PHARMACEUTICAL ANTITUMOR PREPARATION CONTAINING SUCH A NITROSOURUM DERIVATIVE AND THE PREPARED PHARMACEUTICAL PREPARATION.
NL182283C (en) METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION
NL7706888A (en) METHOD OF PREPARING A PHARMACEUTICAL PREPARATION.
NL176637C (en) METHOD FOR PREPARING A HAPTOGLOBINE CONTAINING PREPARATION
NL7706619A (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION.
NL7707849A (en) METHOD OF PREPARING A PHARMACEUTICAL PREPARATION.
NL187239C (en) N-SUBSTITUTED 2-CYANAZIRIDINE DERIVATIVE, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL PREPARATION CONTAINING SUCH A PREPARATION.
NL174347C (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION CONTAINING A (ALKOXY-BENZAMIDE) -PYRROLIDINE AND A BENZAMIDE DERIVATIVE.
NL7708807A (en) METHOD OF PREPARING A PHARMACEUTICAL PREPARATION.
NL7706620A (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION.
NL7600745A (en) PROCEDURE FOR PREPARING A FUNGICIDE PREPARATION.
NL7703474A (en) CEPHALOSPORIN DERIVATIVE, METHOD FOR PREPARING IT, METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION USING IT AND PREPARATION SO OBTAINED.
NL7612667A (en) PROCEDURE FOR PREPARING NOCARDICINE A.
NL7700948A (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND SUBSTITUTED ALANINE COMPOUNDS.
NL7700947A (en) PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND SUBSTITUTED ALANINE COMPOUNDS.

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BX A request for additional search has been filed
BY An additional search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 970128