SE466208B - Enkelstraengad aminoderivat av oligonukleotider och foerfarande foer framstaellning daerav - Google Patents
Enkelstraengad aminoderivat av oligonukleotider och foerfarande foer framstaellning daeravInfo
- Publication number
- SE466208B SE466208B SE8406484A SE8406484A SE466208B SE 466208 B SE466208 B SE 466208B SE 8406484 A SE8406484 A SE 8406484A SE 8406484 A SE8406484 A SE 8406484A SE 466208 B SE466208 B SE 466208B
- Authority
- SE
- Sweden
- Prior art keywords
- oligonucleotide
- deoxy
- amino group
- group
- phosphoramidite
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56501083A | 1983-12-20 | 1983-12-20 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8406484D0 SE8406484D0 (sv) | 1984-12-19 |
SE8406484L SE8406484L (sv) | 1985-06-21 |
SE466208B true SE466208B (sv) | 1992-01-13 |
Family
ID=24256835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8406484A SE466208B (sv) | 1983-12-20 | 1984-12-19 | Enkelstraengad aminoderivat av oligonukleotider och foerfarande foer framstaellning daerav |
Country Status (6)
Country | Link |
---|---|
JP (3) | JPS60197698A (de) |
CA (1) | CA1244786A (de) |
DE (1) | DE3446635C2 (de) |
FR (1) | FR2556726B1 (de) |
GB (1) | GB2153356B (de) |
SE (1) | SE466208B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1223831A (en) | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
US4849513A (en) * | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
US5118800A (en) * | 1983-12-20 | 1992-06-02 | California Institute Of Technology | Oligonucleotides possessing a primary amino group in the terminal nucleotide |
US5015733A (en) * | 1983-12-20 | 1991-05-14 | California Institute Of Technology | Nucleosides possessing blocked aliphatic amino groups |
USRE43096E1 (en) | 1984-01-16 | 2012-01-10 | California Institute Of Technology | Tagged extendable primers and extension products |
US5821058A (en) * | 1984-01-16 | 1998-10-13 | California Institute Of Technology | Automated DNA sequencing technique |
GB8509880D0 (en) * | 1985-04-17 | 1985-05-22 | Ici Plc | Testing device |
US4762779A (en) * | 1985-06-13 | 1988-08-09 | Amgen Inc. | Compositions and methods for functionalizing nucleic acids |
US4757141A (en) * | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
US4959463A (en) * | 1985-10-15 | 1990-09-25 | Genentech, Inc. | Intermediates |
US4855225A (en) * | 1986-02-07 | 1989-08-08 | Applied Biosystems, Inc. | Method of detecting electrophoretically separated oligonucleotides |
DE3642939A1 (de) * | 1986-06-03 | 1987-12-10 | Europ Lab Molekularbiolog | Verfahren zur dna-markierung |
US5242796A (en) * | 1986-07-02 | 1993-09-07 | E. I. Du Pont De Nemours And Company | Method, system and reagents for DNA sequencing |
CA1340806C (en) * | 1986-07-02 | 1999-11-02 | James Merrill Prober | Method, system and reagents for dna sequencing |
US4904582A (en) * | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
US4833332A (en) * | 1987-06-12 | 1989-05-23 | E. I. Du Pont De Nemours And Company | Scanning fluorescent detection system |
US4965349A (en) * | 1987-12-24 | 1990-10-23 | Applied Biosystems, Inc. | Method of synthesizing oligonucleotides labeled with ammonia-labile groups on solid phase supports |
US4997928A (en) * | 1988-09-15 | 1991-03-05 | E. I. Du Pont De Nemours And Company | Fluorescent reagents for the preparation of 5'-tagged oligonucleotides |
US5262536A (en) * | 1988-09-15 | 1993-11-16 | E. I. Du Pont De Nemours And Company | Reagents for the preparation of 5'-tagged oligonucleotides |
GB8822228D0 (en) * | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
CA2098187A1 (en) * | 1990-12-11 | 1992-06-11 | Clifford M. Chan | Methods for labelling oligonucleotides |
US5643722A (en) * | 1994-05-11 | 1997-07-01 | Trustees Of Boston University | Methods for the detection and isolation of proteins |
US6020481A (en) * | 1996-04-01 | 2000-02-01 | The Perkin-Elmer Corporation | Asymmetric benzoxanthene dyes |
SE522077C2 (sv) | 1997-09-05 | 2004-01-13 | Lightup Technologies Ab | Förfarande att välja sekvens hos sond för nukleinsyrahybridisering |
DE19815864A1 (de) | 1998-04-08 | 1999-10-14 | Europ Lab Molekularbiolog | 5'-modifizierte Nukleotide und ihre Anwendung in der Molekularbiologie und Medizin |
EP1163251A1 (de) | 1999-03-24 | 2001-12-19 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | N-acylphosphoramiditen und ihre verwendung in oligonukleotidsynthesen |
WO2003048179A2 (en) | 2001-12-03 | 2003-06-12 | The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services | Thermolabile hydroxyl protecting groups and methods of use |
US9809824B2 (en) | 2004-12-13 | 2017-11-07 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3284440A (en) * | 1964-06-12 | 1966-11-08 | Merck & Co Inc | Phosphate esters of cytosine arabinoide and process for preparing same |
US3847898A (en) * | 1969-05-27 | 1974-11-12 | Upjohn Co | N4-trihaloethoxy carbonyl arabino-furanosyl cytosine 5'-esters |
IL57571A (en) * | 1978-06-22 | 1983-03-31 | Miles Lab | Flavin adenine dinucleotide-labeled conjugates and their use in a homogeneous immunoassay method for determining haptens |
DE2924249C2 (de) * | 1978-06-22 | 1989-04-27 | Miles, Inc., Elkhart, Ind., Us | Spezifische bindungs-untersuchungsmethode zur bestimmung eines liganden in einem fluessigen medium und reagentien zur durchfuehrung dieser methode |
US4415732A (en) * | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
FR2519005B1 (fr) * | 1981-12-29 | 1985-10-25 | Pasteur Institut | Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn |
-
1984
- 1984-12-19 CA CA000470476A patent/CA1244786A/en not_active Expired
- 1984-12-19 JP JP59266525A patent/JPS60197698A/ja active Granted
- 1984-12-19 FR FR8419462A patent/FR2556726B1/fr not_active Expired
- 1984-12-19 SE SE8406484A patent/SE466208B/sv not_active IP Right Cessation
- 1984-12-20 DE DE19843446635 patent/DE3446635C2/de not_active Expired - Lifetime
- 1984-12-20 GB GB08432205A patent/GB2153356B/en not_active Expired
-
1988
- 1988-10-06 JP JP25102888A patent/JPH01250393A/ja active Granted
-
1992
- 1992-04-14 JP JP11959792A patent/JPH0678353B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPS60197698A (ja) | 1985-10-07 |
FR2556726A1 (fr) | 1985-06-21 |
CA1244786A (en) | 1988-11-15 |
FR2556726B1 (fr) | 1987-02-20 |
JPH0157119B2 (de) | 1989-12-04 |
DE3446635A1 (de) | 1985-06-27 |
JPH0678353B2 (ja) | 1994-10-05 |
SE8406484L (sv) | 1985-06-21 |
DE3446635C2 (de) | 1997-08-07 |
JPH06145192A (ja) | 1994-05-24 |
GB2153356B (en) | 1987-07-22 |
JPH01250393A (ja) | 1989-10-05 |
GB8432205D0 (en) | 1985-01-30 |
GB2153356A (en) | 1985-08-21 |
SE8406484D0 (sv) | 1984-12-19 |
JPH0460600B2 (de) | 1992-09-28 |
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