SE464707B - Nya 2-(difenylmetylpiperazinyl)-1-fenyletanol-derivat, foerfarande foer deras framstaellning samt farmaceutiskt preparat - Google Patents

Nya 2-(difenylmetylpiperazinyl)-1-fenyletanol-derivat, foerfarande foer deras framstaellning samt farmaceutiskt preparat

Info

Publication number
SE464707B
SE464707B SE8304071A SE8304071A SE464707B SE 464707 B SE464707 B SE 464707B SE 8304071 A SE8304071 A SE 8304071A SE 8304071 A SE8304071 A SE 8304071A SE 464707 B SE464707 B SE 464707B
Authority
SE
Sweden
Prior art keywords
group
carbon atoms
lower alkoxy
hydrogen atom
alkoxy group
Prior art date
Application number
SE8304071A
Other languages
English (en)
Swedish (sv)
Other versions
SE8304071L (sv
SE8304071D0 (sv
Inventor
M Masaki
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of SE8304071D0 publication Critical patent/SE8304071D0/xx
Publication of SE8304071L publication Critical patent/SE8304071L/xx
Publication of SE464707B publication Critical patent/SE464707B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8304071A 1982-12-02 1983-07-20 Nya 2-(difenylmetylpiperazinyl)-1-fenyletanol-derivat, foerfarande foer deras framstaellning samt farmaceutiskt preparat SE464707B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57212036A JPS59101475A (ja) 1982-12-02 1982-12-02 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤

Publications (3)

Publication Number Publication Date
SE8304071D0 SE8304071D0 (sv) 1983-07-20
SE8304071L SE8304071L (sv) 1984-06-03
SE464707B true SE464707B (sv) 1991-06-03

Family

ID=16615802

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8304071A SE464707B (sv) 1982-12-02 1983-07-20 Nya 2-(difenylmetylpiperazinyl)-1-fenyletanol-derivat, foerfarande foer deras framstaellning samt farmaceutiskt preparat

Country Status (11)

Country Link
US (1) US4528194A (es)
JP (1) JPS59101475A (es)
KR (1) KR900003277B1 (es)
BR (1) BR8304319A (es)
CH (1) CH655719A5 (es)
DE (1) DE3326148A1 (es)
ES (2) ES8604911A1 (es)
FR (1) FR2541275B1 (es)
GB (2) GB8318683D0 (es)
IT (1) IT1162913B (es)
SE (1) SE464707B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPS61161272A (ja) * 1985-01-11 1986-07-21 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
JPH08776B2 (ja) * 1986-08-20 1996-01-10 日本ケミフア株式会社 脳細胞保護作用を有する医薬組成物
EP0354068B1 (en) * 1988-08-05 1994-06-15 Nippon Chemiphar Co., Ltd. Optically active piperazine derivative
JP2679872B2 (ja) * 1989-04-28 1997-11-19 明治製菓株式会社 Ｎ−置換ピペラジン誘導体を含む脳機能障害改善剤
WO1990013539A1 (en) * 1989-04-28 1990-11-15 Meiji Seika Kaisha, Ltd. New n-substituted piperazine derivatives and drug for improving functional disorder of brain
DE4108527A1 (de) * 1991-03-15 1992-09-17 Basf Ag Neue 1-(4-cyano-4-aryl-cyclohexyl)piperazine, ihre herstellung und verwendung
DE4404249C2 (de) * 1994-02-10 2001-10-18 Basf Ag Substituierte Cycloalkyl-piperazinyl-ethanol, ihre Herstellung und diese enthaltende Arzneimittel
KR100472086B1 (ko) * 2001-11-23 2005-02-21 한국화학연구원 항산화 활성을 갖는 3,5-디알콕시-4-히드록시페닐기로치환된 피페라진 유도체, 그의 제조방법 및 이를 포함하는약학적 조성물
US8186436B2 (en) * 2009-09-10 2012-05-29 Warren Carlos Thermal insulating packer fluid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131192C (es) * 1965-06-16
FR2081579B1 (es) * 1970-03-18 1973-04-06 Delalande Sa
FR2163358A1 (en) * 1971-12-15 1973-07-27 Synthelabo Phenylalkanolamine derivs - with effects on the smooth musculature
NL7306771A (es) * 1972-06-02 1973-12-04
JPS504087A (es) * 1973-05-17 1975-01-16

Also Published As

Publication number Publication date
GB2131016A (en) 1984-06-13
ES543397A0 (es) 1986-01-01
KR840006983A (ko) 1984-12-04
CH655719A5 (fr) 1986-05-15
IT1162913B (it) 1987-04-01
FR2541275A1 (fr) 1984-08-24
SE8304071L (sv) 1984-06-03
GB2131016B (en) 1985-11-20
US4528194A (en) 1985-07-09
GB8318683D0 (en) 1983-08-10
ES8604911A1 (es) 1986-03-16
JPH0254832B2 (es) 1990-11-22
KR900003277B1 (ko) 1990-05-12
ES524283A0 (es) 1986-03-16
DE3326148A1 (de) 1984-06-07
DE3326148C2 (es) 1989-11-16
ES8603449A1 (es) 1986-01-01
SE8304071D0 (sv) 1983-07-20
IT8367776A0 (it) 1983-07-19
GB8319317D0 (en) 1983-08-17
BR8304319A (pt) 1984-11-06
JPS59101475A (ja) 1984-06-12
FR2541275B1 (fr) 1986-02-07

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