SE454777B - 5-substituerade 3-aminoalkyl-1h-indoler, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren - Google Patents

5-substituerade 3-aminoalkyl-1h-indoler, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren

Info

Publication number
SE454777B
SE454777B SE8104783A SE8104783A SE454777B SE 454777 B SE454777 B SE 454777B SE 8104783 A SE8104783 A SE 8104783A SE 8104783 A SE8104783 A SE 8104783A SE 454777 B SE454777 B SE 454777B
Authority
SE
Sweden
Prior art keywords
group
compound
formula
hydrogen atom
methyl
Prior art date
Application number
SE8104783A
Other languages
English (en)
Swedish (sv)
Other versions
SE8104783L (sv
Inventor
I H Coates
K Mills
C F Webb
M D Dowle
D E Bays
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8104783L publication Critical patent/SE8104783L/xx
Publication of SE454777B publication Critical patent/SE454777B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
SE8104783A 1980-08-12 1981-08-11 5-substituerade 3-aminoalkyl-1h-indoler, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren SE454777B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8026288 1980-08-12
GB8026287 1980-08-12

Publications (2)

Publication Number Publication Date
SE8104783L SE8104783L (sv) 1982-02-13
SE454777B true SE454777B (sv) 1988-05-30

Family

ID=26276534

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104783A SE454777B (sv) 1980-08-12 1981-08-11 5-substituerade 3-aminoalkyl-1h-indoler, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren

Country Status (12)

Country Link
AU (1) AU550010B2 (OSRAM)
CH (1) CH652394A5 (OSRAM)
DE (1) DE3131752A1 (OSRAM)
DK (1) DK157995C (OSRAM)
ES (2) ES8300699A1 (OSRAM)
FR (1) FR2488606A1 (OSRAM)
GB (1) GB2083463B (OSRAM)
IE (1) IE51493B1 (OSRAM)
IT (1) IT1171450B (OSRAM)
NL (1) NL8103764A (OSRAM)
NZ (1) NZ197998A (OSRAM)
SE (1) SE454777B (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
PT78358B (en) * 1983-04-07 1986-05-30 Smith Kline French Lab Chemical process
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
GB9104136D0 (en) * 1991-02-27 1991-04-17 Merck Sharp & Dohme Therapeutic agents
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
PL172232B1 (pl) * 1992-04-10 1997-08-29 Pfizer Pochodne acyloaminoindolu PL PL PL PL PL PL PL PL
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
JPH10509721A (ja) * 1994-12-06 1998-09-22 メルク シヤープ エンド ドーム リミテツド ５ｈｔ１レセプターアゴニストとしてのアゼチジン、ピロリジン及びピペリジン誘導体
FR2731224B1 (fr) * 1995-03-02 1997-05-30 Pf Medicament Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870162A (en) * 1954-04-28 1959-01-20 Upjohn Co Production of certain tryptamines and compounds produced in the process
FR1203195A (fr) * 1958-07-25 1960-01-15 Chimiotherapie Lab Franc Procédé de préparation d'un nouveau dérivé de la tryptamine
NL7316677A (OSRAM) * 1972-12-21 1974-06-25
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
AU7399581A (en) 1982-02-18
ES504694A0 (es) 1982-11-01
FR2488606A1 (fr) 1982-02-19
IT8149085A1 (it) 1983-02-11
IE51493B1 (en) 1987-01-07
DK157995C (da) 1990-08-06
NL8103764A (nl) 1982-03-01
NZ197998A (en) 1985-08-16
GB2083463A (en) 1982-03-24
ES513934A0 (es) 1984-06-01
IT8149085A0 (it) 1981-08-11
DE3131752A1 (de) 1982-06-16
FR2488606B1 (OSRAM) 1984-10-26
ES8300699A1 (es) 1982-11-01
IE811832L (en) 1982-02-12
DK157995B (da) 1990-03-12
ES8405371A1 (es) 1984-06-01
DE3131752C2 (OSRAM) 1992-04-23
GB2083463B (en) 1984-05-10
DK357281A (da) 1982-02-13
SE8104783L (sv) 1982-02-13
IT1171450B (it) 1987-06-10
CH652394A5 (fr) 1985-11-15
AU550010B2 (en) 1986-02-27

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