SE446267B - Nya kinolylguanidinderivat, forfaranden for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat - Google Patents

Nya kinolylguanidinderivat, forfaranden for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat

Info

Publication number
SE446267B
SE446267B SE7811457A SE7811457A SE446267B SE 446267 B SE446267 B SE 446267B SE 7811457 A SE7811457 A SE 7811457A SE 7811457 A SE7811457 A SE 7811457A SE 446267 B SE446267 B SE 446267B
Authority
SE
Sweden
Prior art keywords
formula
compound
acid
group
meanings given
Prior art date
Application number
SE7811457A
Other languages
English (en)
Swedish (sv)
Other versions
SE7811457L (sv
Inventor
S Rachlin
E Arrigoni-Martelli
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of SE7811457L publication Critical patent/SE7811457L/xx
Publication of SE446267B publication Critical patent/SE446267B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
SE7811457A 1977-11-07 1978-11-06 Nya kinolylguanidinderivat, forfaranden for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat SE446267B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4616677 1977-11-07

Publications (2)

Publication Number Publication Date
SE7811457L SE7811457L (sv) 1979-05-08
SE446267B true SE446267B (sv) 1986-08-25

Family

ID=10440127

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7811457A SE446267B (sv) 1977-11-07 1978-11-06 Nya kinolylguanidinderivat, forfaranden for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat

Country Status (24)

Country Link
US (1) US4293549A (xx)
JP (1) JPS5473784A (xx)
AT (1) AT366368B (xx)
AU (1) AU517670B2 (xx)
BE (1) BE871807A (xx)
CA (1) CA1120929A (xx)
CH (1) CH645354A5 (xx)
DE (1) DE2847792A1 (xx)
DK (1) DK153950C (xx)
ES (1) ES474900A1 (xx)
FI (1) FI69463C (xx)
FR (1) FR2407930A1 (xx)
GR (1) GR65010B (xx)
IE (1) IE47458B1 (xx)
IT (1) IT1100075B (xx)
LU (1) LU80476A1 (xx)
NL (1) NL7811035A (xx)
NZ (1) NZ188770A (xx)
PH (1) PH16296A (xx)
PT (1) PT68750A (xx)
SE (1) SE446267B (xx)
SU (1) SU828967A3 (xx)
YU (1) YU41129B (xx)
ZA (1) ZA786175B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306846B1 (en) * 1972-05-31 2001-10-23 John R. J. Sorenson Anti-inflammatory and anti-ulcer compounds and process
IT1205640B (it) * 1983-04-06 1989-03-23 Yason Srl Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
US4563460A (en) * 1984-01-13 1986-01-07 William H. Rorer, Inc. Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions
HU195487B (en) * 1985-06-04 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for producing quinoline derivatives
EP0259085B1 (en) * 1986-08-29 1991-08-21 Pfizer Inc. 2-guanidino-4-arylthiazoles for treatment of peptic ulcers
US6100260A (en) * 1997-04-21 2000-08-08 Sumitomo Pharmaceutical Company, Limited Isoxazole derivatives
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
US6410561B1 (en) * 1998-03-26 2002-06-25 Japan Tobacco Inc. Amide derivatives and nociceptin antagonists
CA2389773A1 (en) * 1999-11-05 2001-05-10 Robert Glen Activators of soluble guanylate cyclase
US7186725B2 (en) * 2003-01-03 2007-03-06 Genzyme Corporation Anti-inflammatory compositions and methods
JP4613157B2 (ja) * 2003-01-14 2011-01-12 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
GB0404434D0 (en) * 2004-02-27 2004-03-31 Novartis Ag Organic compounds
WO2007022964A2 (de) * 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
CN117677386A (zh) * 2021-07-23 2024-03-08 瓦伦塔有限责任公司 具有亲溶酶体和抗病毒活性的化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB889282A (en) * 1957-05-07 1962-02-14 Air Reduction Preparation of hexafluorodiethyl ether and medicinal compositions containing it
GB889262A (en) * 1959-07-03 1962-02-14 Ciba Ltd Quinoline compounds
US3159676A (en) * 1962-02-07 1964-12-01 Smith Kline French Lab Naphthyl containing guanidines
US3852293A (en) 1972-06-21 1974-12-03 Uniroyal Inc 4-phenyl-2-(3-pyridyl)-thiazole carboxamides
US4000279A (en) * 1974-10-29 1976-12-28 Armour Pharmaceutical Company Pharmaceutical preparations containing 5'-(8'-hydroxyquinolyl)guanidine compounds and methods of using same

Also Published As

Publication number Publication date
AT366368B (de) 1982-04-13
SU828967A3 (ru) 1981-05-07
FR2407930B1 (xx) 1983-03-18
DE2847792C2 (xx) 1988-02-04
BE871807A (fr) 1979-05-07
CH645354A5 (de) 1984-09-28
NL7811035A (nl) 1979-05-09
AU517670B2 (en) 1981-08-20
DK493378A (da) 1979-05-08
IT7829514A0 (it) 1978-11-07
GR65010B (en) 1980-06-12
JPS5473784A (en) 1979-06-13
AU4137678A (en) 1979-05-17
ES474900A1 (es) 1980-04-16
DK153950B (da) 1988-09-26
NZ188770A (en) 1984-07-31
CA1120929A (en) 1982-03-30
SE7811457L (sv) 1979-05-08
FI69463B (fi) 1985-10-31
IT1100075B (it) 1985-09-28
PH16296A (en) 1983-09-05
US4293549A (en) 1981-10-06
DE2847792A1 (de) 1979-05-10
DK153950C (da) 1989-02-20
JPS6348873B2 (xx) 1988-09-30
FI69463C (fi) 1986-02-10
ZA786175B (en) 1979-10-31
YU257578A (en) 1983-01-21
FR2407930A1 (fr) 1979-06-01
LU80476A1 (fr) 1979-06-15
IE47458B1 (en) 1984-03-21
FI783327A (fi) 1979-05-08
PT68750A (en) 1978-12-01
IE782084L (en) 1979-05-07
ATA773278A (de) 1981-08-15
YU41129B (en) 1986-12-31

Similar Documents

Publication Publication Date Title
SU1400508A3 (ru) Способ получени производных арилтиазолов
SE446267B (sv) Nya kinolylguanidinderivat, forfaranden for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat
US3995039A (en) Pyrazolo [1,5-a] [1,3,5] triazines
SE416049B (sv) Forfarande for framstellning av 1,1-diaminoctylenderivat, som kan anvendas for hemning av vissa histaminverkningar
US4174397A (en) Thiazolidine derivatives
IE53274B1 (en) Chemical compounds derived from cyclobutene
HU198033B (en) Process for production of n-benzhydril-diaz-cycloalkilalcane-anilides and medical preparatives containing these compounds as active substance
US20040077649A1 (en) Novel cannabimimetic ligands
NZ206614A (en) Dihydropyridine derivatives and pharmaceutical compositions
HU187478B (en) Process for preparing new imidazolyl-phenyl-amidines and pharmaceutical compositions containing thereof
SE452884B (sv) Ergolinderivat, forfarande for deras framstellning och farmaceutiska kompositioner der de ingar
JPS609716B2 (ja) １，２―ベンズインチアゾリン―３―オン類、それらの製造法および医薬としての使用
AU596869B2 (en) 2-(thio-linked)-pyridine-5-(4,5-dihydro-2-oxazolyl)-(thieno( 2,3-d)-imidazoles and -benzimidazoles), a process for their preparation, and their use
JPS62252780A (ja) 新規なインデノチアゾ−ル誘導体及びその製造法
SE455701B (sv) Svavelhaltiga isokinolinderivat samt farmaceutiska beredningar innehalllande dem
CA1058208A (en) Pharmaceutical n,n'(phenylphenylene) dioxamic acid derivatives
SE452462B (sv) Nya 2-guanidinotiazolderivat
EP0093515B1 (en) Tricyclic triazino compounds, their use and formulation as pharmaceuticals and processes for their production
US4064270A (en) N'-(Aminoacylaminophenyl) acetamidines
CA1075240A (en) 4,5,6,7-tetrahydroimidazo-(4,5-c)-pyridine derivatives
EP0126894B1 (en) Tropone derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
CA1095524A (en) Antiinflammatory imidazothiazoles
HU196386B (en) Process for production of derivatives of substituated ethan-diimid-amid
KR900001885B1 (ko) 5-클로로-s-트리아졸로[4, 3-a]피리딘-7-카복실산 및 그의 제조방법
EP0119541A1 (en) Substituted 4,10-dihydro-10-oxothieno-benzoxepins, a process for their preparation and their use as medicaments

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7811457-6

Effective date: 19930610

Format of ref document f/p: F