LU80476A1 - Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation - Google Patents

Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation

Info

Publication number
LU80476A1
LU80476A1 LU80476A LU80476A LU80476A1 LU 80476 A1 LU80476 A1 LU 80476A1 LU 80476 A LU80476 A LU 80476A LU 80476 A LU80476 A LU 80476A LU 80476 A1 LU80476 A1 LU 80476A1
Authority
LU
Luxembourg
Prior art keywords
guanidines
quinolyl
inflammatory
useful
new
Prior art date
Application number
LU80476A
Other languages
English (en)
French (fr)
Inventor
Rachlin Schneur
Arrigoni-Martelli Edoardo
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of LU80476A1 publication Critical patent/LU80476A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
LU80476A 1977-11-07 1978-11-06 Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation LU80476A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4616677 1977-11-07

Publications (1)

Publication Number Publication Date
LU80476A1 true LU80476A1 (fr) 1979-06-15

Family

ID=10440127

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80476A LU80476A1 (fr) 1977-11-07 1978-11-06 Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation

Country Status (24)

Country Link
US (1) US4293549A (xx)
JP (1) JPS5473784A (xx)
AT (1) AT366368B (xx)
AU (1) AU517670B2 (xx)
BE (1) BE871807A (xx)
CA (1) CA1120929A (xx)
CH (1) CH645354A5 (xx)
DE (1) DE2847792A1 (xx)
DK (1) DK153950C (xx)
ES (1) ES474900A1 (xx)
FI (1) FI69463C (xx)
FR (1) FR2407930A1 (xx)
GR (1) GR65010B (xx)
IE (1) IE47458B1 (xx)
IT (1) IT1100075B (xx)
LU (1) LU80476A1 (xx)
NL (1) NL7811035A (xx)
NZ (1) NZ188770A (xx)
PH (1) PH16296A (xx)
PT (1) PT68750A (xx)
SE (1) SE446267B (xx)
SU (1) SU828967A3 (xx)
YU (1) YU41129B (xx)
ZA (1) ZA786175B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306846B1 (en) * 1972-05-31 2001-10-23 John R. J. Sorenson Anti-inflammatory and anti-ulcer compounds and process
IT1205640B (it) * 1983-04-06 1989-03-23 Yason Srl Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
US4563460A (en) * 1984-01-13 1986-01-07 William H. Rorer, Inc. Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions
HU195487B (en) * 1985-06-04 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for producing quinoline derivatives
DE3772301D1 (de) * 1986-08-29 1991-09-26 Pfizer 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren.
US6100260A (en) * 1997-04-21 2000-08-08 Sumitomo Pharmaceutical Company, Limited Isoxazole derivatives
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
WO1999048492A1 (fr) 1998-03-26 1999-09-30 Japan Tobacco Inc. Derives d'amide et antagonistes de nociceptine
EP1237849A1 (en) * 1999-11-05 2002-09-11 University College London Activators of soluble guanylate cyclase
US7186725B2 (en) * 2003-01-03 2007-03-06 Genzyme Corporation Anti-inflammatory compositions and methods
KR20050100615A (ko) * 2003-01-14 2005-10-19 싸이토키네틱스, 인코포레이티드 화합물, 조성물 및 방법
GB0404434D0 (en) 2004-02-27 2004-03-31 Novartis Ag Organic compounds
EP1917244A2 (de) * 2005-08-24 2008-05-07 Abbott GmbH & Co. KG Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
WO2023003497A1 (ru) * 2021-07-23 2023-01-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Соединения с лизосомотропной и противовирусной активностью

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB889282A (en) * 1957-05-07 1962-02-14 Air Reduction Preparation of hexafluorodiethyl ether and medicinal compositions containing it
GB889262A (en) * 1959-07-03 1962-02-14 Ciba Ltd Quinoline compounds
US3159676A (en) * 1962-02-07 1964-12-01 Smith Kline French Lab Naphthyl containing guanidines
US3852293A (en) 1972-06-21 1974-12-03 Uniroyal Inc 4-phenyl-2-(3-pyridyl)-thiazole carboxamides
US4000279A (en) * 1974-10-29 1976-12-28 Armour Pharmaceutical Company Pharmaceutical preparations containing 5'-(8'-hydroxyquinolyl)guanidine compounds and methods of using same

Also Published As

Publication number Publication date
IE782084L (en) 1979-05-07
DE2847792C2 (xx) 1988-02-04
IT7829514A0 (it) 1978-11-07
SE446267B (sv) 1986-08-25
GR65010B (en) 1980-06-12
FR2407930A1 (fr) 1979-06-01
JPS5473784A (en) 1979-06-13
AT366368B (de) 1982-04-13
SE7811457L (sv) 1979-05-08
NZ188770A (en) 1984-07-31
FI69463B (fi) 1985-10-31
AU4137678A (en) 1979-05-17
JPS6348873B2 (xx) 1988-09-30
US4293549A (en) 1981-10-06
DK153950C (da) 1989-02-20
YU257578A (en) 1983-01-21
DE2847792A1 (de) 1979-05-10
CA1120929A (en) 1982-03-30
BE871807A (fr) 1979-05-07
ATA773278A (de) 1981-08-15
DK153950B (da) 1988-09-26
NL7811035A (nl) 1979-05-09
FI69463C (fi) 1986-02-10
ZA786175B (en) 1979-10-31
YU41129B (en) 1986-12-31
IT1100075B (it) 1985-09-28
PT68750A (en) 1978-12-01
PH16296A (en) 1983-09-05
IE47458B1 (en) 1984-03-21
AU517670B2 (en) 1981-08-20
ES474900A1 (es) 1980-04-16
FR2407930B1 (xx) 1983-03-18
FI783327A (fi) 1979-05-08
SU828967A3 (ru) 1981-05-07
DK493378A (da) 1979-05-08
CH645354A5 (de) 1984-09-28

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