BE853607A - Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation - Google Patents

Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation

Info

Publication number
BE853607A
BE853607A BE176726A BE176726A BE853607A BE 853607 A BE853607 A BE 853607A BE 176726 A BE176726 A BE 176726A BE 176726 A BE176726 A BE 176726A BE 853607 A BE853607 A BE 853607A
Authority
BE
Belgium
Prior art keywords
penicillanoyloxyalcanes
antibiotics
useful
preparation process
new bis
Prior art date
Application number
BE176726A
Other languages
English (en)
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of BE853607A publication Critical patent/BE853607A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/06—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE176726A 1976-04-15 1977-04-14 Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation BE853607A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB15746/76A GB1579931A (en) 1976-04-15 1976-04-15 Bis-penicillanoyl-oxy-alkanes

Publications (1)

Publication Number Publication Date
BE853607A true BE853607A (fr) 1977-08-01

Family

ID=10064756

Family Applications (1)

Application Number Title Priority Date Filing Date
BE176726A BE853607A (fr) 1976-04-15 1977-04-14 Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation

Country Status (24)

Country Link
US (1) US4181659A (fr)
JP (1) JPS52128391A (fr)
AR (1) AR218870A1 (fr)
AT (1) AT353960B (fr)
AU (1) AU510825B2 (fr)
BE (1) BE853607A (fr)
CA (1) CA1112239A (fr)
DE (1) DE2716172C2 (fr)
DK (1) DK144376C (fr)
ES (1) ES457829A1 (fr)
FI (1) FI63759C (fr)
FR (1) FR2348217A1 (fr)
GB (1) GB1579931A (fr)
GR (1) GR63089B (fr)
IE (1) IE44809B1 (fr)
IT (1) IT1116735B (fr)
LU (1) LU77135A1 (fr)
NL (1) NL7704085A (fr)
NZ (1) NZ183756A (fr)
PH (1) PH14046A (fr)
PT (1) PT66434B (fr)
SE (1) SE425490B (fr)
YU (1) YU94277A (fr)
ZA (1) ZA771935B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE49880B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives
US4407751A (en) * 1979-02-13 1983-10-04 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Processes for preparing β-lactams
DE3051044C2 (fr) * 1979-06-19 1989-03-30 Leo Pharmaceutical Products Ltd. A/S (Loevens Kemiske Fabrik Produktionsaktieselskab), Ballerup, Dk
US4340539A (en) * 1980-01-21 1982-07-20 Bristol-Myers Company Derivatives of 6-bromo penicillanic acid
US4323499A (en) * 1981-01-05 1982-04-06 Pfizer Inc. 6-(2-Aryl-2-(1,1-dioxopenicillanoyloxy-methoxycarbonyl)acetamido penicillanic acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957764A (en) * 1969-11-11 1976-05-18 Lovens Kemiske Fabrik Produktionsaktieselskab 6-aminopenicillanic acid derivatives
BE758782A (fr) * 1969-11-11 1971-05-10 Leo Pharm Prod Ltd Nouveaux derives d'acide 6-amidino penicillanique leur procede de preparation et leurs applications comme antibiotiques
GB1303491A (fr) * 1970-03-24 1973-01-17
US3755588A (en) * 1970-11-04 1973-08-28 Leo Pharm Prod Ltd Penicillanic acid in dosage unit form
GB1335718A (en) * 1971-05-05 1973-10-31 Leo Pharm Prod Ltd Penicillin esters salts thereof and methods for their preparation
GB1405886A (en) * 1971-11-01 1975-09-10 Astra Laekemedel Ab Synergistic compositions comprising penicillin and cephalosporin antibiotics
GB1427139A (en) * 1972-03-13 1976-03-10 Astra Laekemedel Ab Penicillins

Also Published As

Publication number Publication date
US4181659A (en) 1980-01-01
DK144376B (da) 1982-03-01
ES457829A1 (es) 1978-03-01
FI63759B (fi) 1983-04-29
YU94277A (en) 1982-10-31
IE44809L (en) 1977-10-15
SE7704311L (sv) 1977-10-16
IT1116735B (it) 1986-02-10
DK162177A (da) 1977-10-16
DK144376C (da) 1982-08-02
AU510825B2 (en) 1980-07-17
FR2348217A1 (fr) 1977-11-10
PT66434B (en) 1978-09-20
NZ183756A (en) 1978-12-18
CA1112239A (fr) 1981-11-10
DE2716172A1 (de) 1977-10-27
DE2716172C2 (de) 1985-09-05
ATA240677A (de) 1979-05-15
AU2428577A (en) 1978-10-19
FI63759C (fi) 1983-08-10
PH14046A (en) 1980-12-29
JPS6129959B2 (fr) 1986-07-10
GR63089B (en) 1979-08-11
SE425490B (sv) 1982-10-04
ZA771935B (en) 1978-02-22
JPS52128391A (en) 1977-10-27
FR2348217B1 (fr) 1980-04-25
AR218870A1 (es) 1980-07-15
PT66434A (en) 1977-05-01
LU77135A1 (fr) 1977-08-12
FI771183A (fr) 1977-10-16
IE44809B1 (en) 1982-04-07
NL7704085A (nl) 1977-10-18
GB1579931A (en) 1980-11-26
AT353960B (de) 1979-12-10

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOVENS KEMIS

Effective date: 19860430