FR2319343A1 - Nouvelles guanidines, leur procede de preparation et leur application - Google Patents
Nouvelles guanidines, leur procede de preparation et leur applicationInfo
- Publication number
- FR2319343A1 FR2319343A1 FR7623453A FR7623453A FR2319343A1 FR 2319343 A1 FR2319343 A1 FR 2319343A1 FR 7623453 A FR7623453 A FR 7623453A FR 7623453 A FR7623453 A FR 7623453A FR 2319343 A1 FR2319343 A1 FR 2319343A1
- Authority
- FR
- France
- Prior art keywords
- application
- preparation process
- guanidines
- new
- new guanidines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB31970/75A GB1564502A (en) | 1975-07-31 | 1975-07-31 | Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2319343A1 true FR2319343A1 (fr) | 1977-02-25 |
| FR2319343B1 FR2319343B1 (fr) | 1978-11-17 |
Family
ID=10331105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7623453A Granted FR2319343A1 (fr) | 1975-07-31 | 1976-07-30 | Nouvelles guanidines, leur procede de preparation et leur application |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | US4083983A (fr) |
| JP (2) | JPS5219671A (fr) |
| AR (1) | AR213736A1 (fr) |
| AT (1) | AT356132B (fr) |
| AU (1) | AU502752B2 (fr) |
| BE (1) | BE844504A (fr) |
| BG (1) | BG27368A3 (fr) |
| CA (1) | CA1068711A (fr) |
| CH (1) | CH624938A5 (fr) |
| CS (1) | CS189018B2 (fr) |
| DD (1) | DD125204A5 (fr) |
| DE (1) | DE2634433A1 (fr) |
| DK (1) | DK316176A (fr) |
| ES (1) | ES450310A1 (fr) |
| FI (1) | FI762193A (fr) |
| FR (1) | FR2319343A1 (fr) |
| GB (1) | GB1564502A (fr) |
| GR (1) | GR60810B (fr) |
| HU (1) | HU173778B (fr) |
| IE (1) | IE43508B1 (fr) |
| IL (1) | IL50005A (fr) |
| LU (1) | LU75507A1 (fr) |
| NL (1) | NL7608496A (fr) |
| NO (1) | NO762661L (fr) |
| PH (1) | PH14555A (fr) |
| PL (1) | PL103684B1 (fr) |
| PT (1) | PT65348B (fr) |
| SE (1) | SE7608477L (fr) |
| SU (1) | SU692558A3 (fr) |
| ZA (1) | ZA764082B (fr) |
| ZM (1) | ZM9876A1 (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2359838A1 (fr) * | 1976-07-28 | 1978-02-24 | Smith Kline French Lab | Guanidines, leur preparation et leur application en therapeutique |
| FR2453155A1 (fr) * | 1979-02-16 | 1980-10-31 | Eisai Co Ltd | Derives de cyanoguanidine, leur procede de preparation et leurs applications en therapeutique |
| EP0066442A1 (fr) * | 1981-05-27 | 1982-12-08 | Smithkline Beckman Corporation | Procédé chimique |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4928863A (fr) * | 1972-07-13 | 1974-03-14 | ||
| JPS5078968U (fr) * | 1973-11-20 | 1975-07-08 | ||
| ZA782129B (en) | 1977-04-20 | 1979-03-28 | Ici Ltd | Hertocyclic derivatives |
| US4165378A (en) | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
| US4233302A (en) * | 1977-12-23 | 1980-11-11 | Glaxo Group Limited | Amine derivatives and pharmaceutical compositions containing them |
| US4282363A (en) * | 1978-11-24 | 1981-08-04 | Bristol-Myers Company | 1-Nitro-2-(2-alkynylamino)-2-[(2-pyridylmethylthio)-ethylamino]ethylene derivatives |
| US4250316A (en) * | 1978-11-24 | 1981-02-10 | Bristol-Myers Company | Pyridyl guanidine anti-ulcer agents |
| SE8204879D0 (sv) * | 1982-08-26 | 1982-08-26 | Haessle Ab | Novel chemical intermediates |
| DE3232462A1 (de) * | 1982-09-01 | 1984-03-01 | Bayer Ag, 5090 Leverkusen | 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPH0828166B2 (ja) * | 1985-01-16 | 1996-03-21 | 松下電器産業株式会社 | サ−モスタツト |
| AU660132B2 (en) * | 1992-12-21 | 1995-06-08 | Bayer Aktiengesellschaft | Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridine |
| US5380734A (en) * | 1993-04-15 | 1995-01-10 | American Home Products Corporation | N-cyanoamidine derivatives as anti-influenza agents |
| EP3813900A4 (fr) | 2018-06-29 | 2022-05-04 | 410 Medical, Inc. | Systèmes, appareil et procédés de filtration d'air à partir d'une ligne de fluide |
| EP4196793A1 (fr) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3968216A (en) * | 1969-10-29 | 1976-07-06 | Smith Kline & French Laboratories Limited | Method of inhibiting histamine activity with guanidine compounds |
| US3908014A (en) * | 1970-06-25 | 1975-09-23 | Smith Kline French Lab | Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives |
| US3808336A (en) | 1970-06-25 | 1974-04-30 | Smithkline Corp | Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives |
| US3905984A (en) * | 1971-03-09 | 1975-09-16 | Smith Kline French Lab | Pyridyl substituted thioalkyl-and oxyalkyl-thioureas and ureas |
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
| GB1397436A (en) * | 1972-09-05 | 1975-06-11 | Smith Kline French Lab | Heterocyclic n-cyanoguinidines |
| US4002759A (en) * | 1973-05-17 | 1977-01-11 | Smith Kline & French Laboratories Limited | Pyridylbutylamino ethylene compounds |
| GB1421792A (en) * | 1973-05-17 | 1976-01-21 | Smith Kline French Lab | Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them |
| US4025527A (en) * | 1973-07-13 | 1977-05-24 | Smith Kline & French Laboratories Limited | Certain thiazoles and oxazoles |
| GB1497260A (en) * | 1974-06-28 | 1978-01-05 | Smith Kline French Lab | Guanidine derivatives |
-
1975
- 1975-07-31 GB GB31970/75A patent/GB1564502A/en not_active Expired
-
1976
- 1976-07-09 PT PT65348A patent/PT65348B/pt unknown
- 1976-07-09 ZA ZA764082A patent/ZA764082B/xx unknown
- 1976-07-09 IL IL50005A patent/IL50005A/xx unknown
- 1976-07-09 PH PH18668A patent/PH14555A/en unknown
- 1976-07-13 DK DK316176A patent/DK316176A/da unknown
- 1976-07-13 US US05/704,877 patent/US4083983A/en not_active Expired - Lifetime
- 1976-07-21 CS CS764841A patent/CS189018B2/cs unknown
- 1976-07-22 CA CA257,590A patent/CA1068711A/fr not_active Expired
- 1976-07-23 ZM ZM98/76A patent/ZM9876A1/xx unknown
- 1976-07-23 BE BE169228A patent/BE844504A/fr not_active IP Right Cessation
- 1976-07-27 SE SE7608477A patent/SE7608477L/xx not_active Application Discontinuation
- 1976-07-27 GR GR51358A patent/GR60810B/el unknown
- 1976-07-27 AT AT552576A patent/AT356132B/de not_active IP Right Cessation
- 1976-07-30 FR FR7623453A patent/FR2319343A1/fr active Granted
- 1976-07-30 BG BG7633887A patent/BG27368A3/xx unknown
- 1976-07-30 NO NO762661A patent/NO762661L/no unknown
- 1976-07-30 PL PL1976191537A patent/PL103684B1/pl unknown
- 1976-07-30 ES ES450310A patent/ES450310A1/es not_active Expired
- 1976-07-30 SU SU762386151A patent/SU692558A3/ru active
- 1976-07-30 JP JP51092245A patent/JPS5219671A/ja active Pending
- 1976-07-30 HU HU76SI1531A patent/HU173778B/hu unknown
- 1976-07-30 FI FI762193A patent/FI762193A/fi not_active Application Discontinuation
- 1976-07-30 IE IE1708/76A patent/IE43508B1/en unknown
- 1976-07-30 NL NL7608496A patent/NL7608496A/xx not_active Application Discontinuation
- 1976-07-30 AR AR264159A patent/AR213736A1/es active
- 1976-07-30 LU LU75507A patent/LU75507A1/xx unknown
- 1976-07-30 DD DD194159A patent/DD125204A5/xx unknown
- 1976-07-30 DE DE19762634433 patent/DE2634433A1/de not_active Withdrawn
- 1976-07-30 CH CH978576A patent/CH624938A5/de not_active IP Right Cessation
- 1976-07-30 AU AU16453/76A patent/AU502752B2/en not_active Expired
-
1979
- 1979-02-21 US US06/013,579 patent/US4215126A/en not_active Expired - Lifetime
- 1979-11-15 US US06/094,412 patent/US4264608A/en not_active Expired - Lifetime
-
1980
- 1980-11-19 US US06/208,370 patent/US4426526A/en not_active Expired - Lifetime
-
1985
- 1985-02-25 JP JP60037341A patent/JPS60243069A/ja active Granted
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2359838A1 (fr) * | 1976-07-28 | 1978-02-24 | Smith Kline French Lab | Guanidines, leur preparation et leur application en therapeutique |
| FR2453155A1 (fr) * | 1979-02-16 | 1980-10-31 | Eisai Co Ltd | Derives de cyanoguanidine, leur procede de preparation et leurs applications en therapeutique |
| EP0066442A1 (fr) * | 1981-05-27 | 1982-12-08 | Smithkline Beckman Corporation | Procédé chimique |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |