SE444439B - Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan - Google Patents

Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan

Info

Publication number
SE444439B
SE444439B SE7807824A SE7807824A SE444439B SE 444439 B SE444439 B SE 444439B SE 7807824 A SE7807824 A SE 7807824A SE 7807824 A SE7807824 A SE 7807824A SE 444439 B SE444439 B SE 444439B
Authority
SE
Sweden
Prior art keywords
solution
dissolved
angiotensin
ile
added
Prior art date
Application number
SE7807824A
Other languages
English (en)
Swedish (sv)
Other versions
SE7807824L (sv
Inventor
L Kisfaludy
G Nyeki
L Szirmai
E Karpati
K Gidai
L Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE7807824L publication Critical patent/SE7807824L/xx
Publication of SE444439B publication Critical patent/SE444439B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7807824A 1977-07-18 1978-07-13 Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan SE444439B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77RI641A HU177134B (en) 1977-07-18 1977-07-18 Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity

Publications (2)

Publication Number Publication Date
SE7807824L SE7807824L (sv) 1979-01-19
SE444439B true SE444439B (sv) 1986-04-14

Family

ID=11001038

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7807824A SE444439B (sv) 1977-07-18 1978-07-13 Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan

Country Status (24)

Country Link
US (1) US4209442A (fi)
JP (1) JPS5831337B2 (fi)
AT (1) AT360678B (fi)
AU (1) AU520176B2 (fi)
BE (1) BE869076A (fi)
CA (1) CA1114810A (fi)
CH (1) CH637916A5 (fi)
CS (1) CS201013B2 (fi)
DD (1) DD137221A5 (fi)
DE (1) DE2831271C2 (fi)
DK (1) DK319578A (fi)
ES (1) ES471791A1 (fi)
FI (1) FI64797C (fi)
FR (1) FR2398049A1 (fi)
GB (1) GB2002779B (fi)
HU (1) HU177134B (fi)
IL (1) IL55075A (fi)
IN (1) IN149852B (fi)
NL (1) NL7807627A (fi)
NO (1) NO148070C (fi)
PL (1) PL111964B1 (fi)
SE (1) SE444439B (fi)
SU (1) SU913940A3 (fi)
YU (1) YU41315B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905502C2 (de) * 1979-02-14 1982-07-15 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin
HU181008B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
FR2546163B1 (fr) * 1983-05-16 1987-10-09 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
JPS60132197A (ja) * 1983-12-02 1985-07-15 日東電工株式会社 管の接合方法
HU191961B (en) * 1984-08-02 1987-04-28 Richter Gedeon Vegyeszet Process for producing 1,5 and 8 substituted peptides of angiotenzin-ii antagonistic activity
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
US4772684A (en) * 1987-01-20 1988-09-20 Triton Biosciences, Inc. Peptides affecting blood pressure regulation
JPH053629Y2 (fi) * 1987-10-09 1993-01-28
RU2355700C9 (ru) * 2000-07-21 2010-03-20 Шеринг Корпорейшн Новые пептиды как ингибиторы ns3-серинпротеазы вируса гепатита с

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886134A (en) * 1970-03-09 1975-05-27 Morton Norwich Products Inc Analogues of angiotensin II
GB1320104A (en) * 1971-05-20 1973-06-13 Norwich Pharma Co Hepta-and octapeptides
US3907762A (en) * 1971-12-27 1975-09-23 Univ Sherbrooke Angiotensin{hd II {B position 8 analogs
DE2323322A1 (de) * 1973-05-09 1974-11-28 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3923771A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus N-Guanidylacetyl-{8 des-asp{hu 1{b -Ile{hu 8{b {9 {0 angiotensin II as an angiotensin antagonist

Also Published As

Publication number Publication date
FR2398049A1 (fr) 1979-02-16
NO782464L (no) 1979-01-19
SU913940A3 (en) 1982-03-15
ATA518378A (de) 1980-06-15
YU41315B (en) 1987-02-28
NO148070B (no) 1983-04-25
DE2831271C2 (de) 1982-02-25
IL55075A (en) 1981-12-31
JPS5831337B2 (ja) 1983-07-05
PL111964B1 (en) 1980-09-30
US4209442A (en) 1980-06-24
GB2002779A (en) 1979-02-28
NL7807627A (nl) 1979-01-22
NO148070C (no) 1983-08-03
DE2831271A1 (de) 1979-03-01
FI64797B (fi) 1983-09-30
CA1114810A (en) 1981-12-22
DK319578A (da) 1979-01-19
YU171578A (en) 1982-10-31
IL55075A0 (en) 1978-09-29
FI782216A (fi) 1979-01-19
AU3800978A (en) 1980-01-17
IN149852B (fi) 1982-05-08
PL208497A1 (pl) 1979-07-02
BE869076A (fr) 1979-01-18
CS201013B2 (en) 1980-10-31
FI64797C (fi) 1984-01-10
JPS5422368A (en) 1979-02-20
SE7807824L (sv) 1979-01-19
GB2002779B (en) 1982-01-27
HU177134B (en) 1981-07-28
CH637916A5 (de) 1983-08-31
ES471791A1 (es) 1979-02-01
AT360678B (de) 1979-04-15
DD137221A5 (de) 1979-08-22
AU520176B2 (en) 1982-01-21
FR2398049B1 (fi) 1984-06-08

Similar Documents

Publication Publication Date Title
US4388304A (en) Angiotensin-II analogues with antagonizing effects, containing an ester group in position 8, and a process for the preparation thereof
US3853837A (en) Novel nonapeptide amide analogs of luteinizing hormone releasing factor
CA1111841A (en) Cyclopeptides
SE444439B (sv) Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan
EP0016611A2 (en) Tripeptides, process for their preparation, therapeutic compositions containing them and methods for their use
EP0016612B1 (en) Peptides having ubiquitin-like activity, process for their preparation, therapeutic compositions containing them and their use
US4179433A (en) Angiotensin II antagonist peptides containing an alpha-aminooxyacid in the position-1
US5786335A (en) Sulfhydryl containing peptides for treating vascular disease
EP0018182B1 (en) Peptides having thymopoietin-like activity, therapeutic compositions containing them, and process for their preparation
US4330532A (en) Angiotensin-II analogues with antagonizing effects, containing an α-hydroxycarboxylic acid residue in position 8, and a process for the preparation thereof
EP0360481B1 (en) New pentapeptide and a process for the preparation thereof
EP0171270A2 (en) Process for the preparation of angiotensin-II analogues substituted in the 1-, 5- and 8-positions
Abiko et al. Syntheses of thymopoietins and their immunological effects: Relationship of amino acid sequence to immunological activity
CA2072390A1 (en) Endothelin analogues with alpha-amine substitution at residue 20
GB2031435A (en) Polypeptides

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7807824-3

Effective date: 19910211

Format of ref document f/p: F