SE444439B - Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan - Google Patents

Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan

Info

Publication number
SE444439B
SE444439B SE7807824A SE7807824A SE444439B SE 444439 B SE444439 B SE 444439B SE 7807824 A SE7807824 A SE 7807824A SE 7807824 A SE7807824 A SE 7807824A SE 444439 B SE444439 B SE 444439B
Authority
SE
Sweden
Prior art keywords
solution
dissolved
angiotensin
ile
added
Prior art date
Application number
SE7807824A
Other languages
English (en)
Swedish (sv)
Other versions
SE7807824L (sv
Inventor
L Kisfaludy
G Nyeki
L Szirmai
E Karpati
K Gidai
L Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE7807824L publication Critical patent/SE7807824L/xx
Publication of SE444439B publication Critical patent/SE444439B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7807824A 1977-07-18 1978-07-13 Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan SE444439B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77RI641A HU177134B (en) 1977-07-18 1977-07-18 Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity

Publications (2)

Publication Number Publication Date
SE7807824L SE7807824L (sv) 1979-01-19
SE444439B true SE444439B (sv) 1986-04-14

Family

ID=11001038

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7807824A SE444439B (sv) 1977-07-18 1978-07-13 Nya angiotensin-ii-analoger, som i l-stellningen innehaller en alifatisk alfa-hydroxikarboxylsyra och som har angiotensinantagoniserande verkan

Country Status (24)

Country Link
US (1) US4209442A (de)
JP (1) JPS5831337B2 (de)
AT (1) AT360678B (de)
AU (1) AU520176B2 (de)
BE (1) BE869076A (de)
CA (1) CA1114810A (de)
CH (1) CH637916A5 (de)
CS (1) CS201013B2 (de)
DD (1) DD137221A5 (de)
DE (1) DE2831271C2 (de)
DK (1) DK319578A (de)
ES (1) ES471791A1 (de)
FI (1) FI64797C (de)
FR (1) FR2398049A1 (de)
GB (1) GB2002779B (de)
HU (1) HU177134B (de)
IL (1) IL55075A (de)
IN (1) IN149852B (de)
NL (1) NL7807627A (de)
NO (1) NO148070C (de)
PL (1) PL111964B1 (de)
SE (1) SE444439B (de)
SU (1) SU913940A3 (de)
YU (1) YU41315B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905502C2 (de) * 1979-02-14 1982-07-15 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
HU181008B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
FR2546163B1 (fr) * 1983-05-16 1987-10-09 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
JPS60132197A (ja) * 1983-12-02 1985-07-15 日東電工株式会社 管の接合方法
HU191961B (en) * 1984-08-02 1987-04-28 Richter Gedeon Vegyeszet Process for producing 1,5 and 8 substituted peptides of angiotenzin-ii antagonistic activity
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
US4772684A (en) * 1987-01-20 1988-09-20 Triton Biosciences, Inc. Peptides affecting blood pressure regulation
JPH053629Y2 (de) * 1987-10-09 1993-01-28
PL206255B1 (pl) * 2000-07-21 2010-07-30 Dendreon Corporationdendreon Corporation Inhibitor proteazy wirusa zapalenia wątroby C, zawierająca go kompozycja farmaceutyczna i zastosowanie inhibitora do wytwarzania leku do leczenia chorób związanych z HCV oraz zastosowanie do wytwarzania kompozycji do stosowania w kombinowanej terapii

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886134A (en) * 1970-03-09 1975-05-27 Morton Norwich Products Inc Analogues of angiotensin II
GB1320104A (en) * 1971-05-20 1973-06-13 Norwich Pharma Co Hepta-and octapeptides
US3907762A (en) * 1971-12-27 1975-09-23 Univ Sherbrooke Angiotensin{hd II {B position 8 analogs
DE2323322A1 (de) * 1973-05-09 1974-11-28 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3923771A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus N-Guanidylacetyl-{8 des-asp{hu 1{b -Ile{hu 8{b {9 {0 angiotensin II as an angiotensin antagonist

Also Published As

Publication number Publication date
DE2831271C2 (de) 1982-02-25
AT360678B (de) 1979-04-15
ATA518378A (de) 1980-06-15
FI782216A (fi) 1979-01-19
GB2002779A (en) 1979-02-28
SE7807824L (sv) 1979-01-19
CH637916A5 (de) 1983-08-31
SU913940A3 (en) 1982-03-15
NL7807627A (nl) 1979-01-22
GB2002779B (en) 1982-01-27
AU520176B2 (en) 1982-01-21
BE869076A (fr) 1979-01-18
FR2398049A1 (fr) 1979-02-16
JPS5831337B2 (ja) 1983-07-05
AU3800978A (en) 1980-01-17
CS201013B2 (en) 1980-10-31
YU41315B (en) 1987-02-28
IN149852B (de) 1982-05-08
HU177134B (en) 1981-07-28
US4209442A (en) 1980-06-24
IL55075A0 (en) 1978-09-29
PL208497A1 (pl) 1979-07-02
CA1114810A (en) 1981-12-22
FR2398049B1 (de) 1984-06-08
JPS5422368A (en) 1979-02-20
NO782464L (no) 1979-01-19
FI64797C (fi) 1984-01-10
NO148070C (no) 1983-08-03
DD137221A5 (de) 1979-08-22
FI64797B (fi) 1983-09-30
DK319578A (da) 1979-01-19
DE2831271A1 (de) 1979-03-01
IL55075A (en) 1981-12-31
YU171578A (en) 1982-10-31
NO148070B (no) 1983-04-25
PL111964B1 (en) 1980-09-30
ES471791A1 (es) 1979-02-01

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