SE440503B - 3-(4-fenyl-1-piperazino-1-yl)-1,2-propandiol-3-(teofyllin-7-yl)-1-propansulfonat, forfarande for framstellning av denna samt lekemedel med antitussiv verkan - Google Patents

3-(4-fenyl-1-piperazino-1-yl)-1,2-propandiol-3-(teofyllin-7-yl)-1-propansulfonat, forfarande for framstellning av denna samt lekemedel med antitussiv verkan

Info

Publication number
SE440503B
SE440503B SE8201184A SE8201184A SE440503B SE 440503 B SE440503 B SE 440503B SE 8201184 A SE8201184 A SE 8201184A SE 8201184 A SE8201184 A SE 8201184A SE 440503 B SE440503 B SE 440503B
Authority
SE
Sweden
Prior art keywords
theophyllin
compound
phenyl
propanediol
piperazino
Prior art date
Application number
SE8201184A
Other languages
English (en)
Swedish (sv)
Other versions
SE8201184L (sv
Inventor
V Pestellini
M Ghelardoni
D Giannotti
A Meli
C A Maggi
Original Assignee
Menarini Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas filed Critical Menarini Sas
Publication of SE8201184L publication Critical patent/SE8201184L/xx
Publication of SE440503B publication Critical patent/SE440503B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SE8201184A 1981-02-25 1982-02-25 3-(4-fenyl-1-piperazino-1-yl)-1,2-propandiol-3-(teofyllin-7-yl)-1-propansulfonat, forfarande for framstellning av denna samt lekemedel med antitussiv verkan SE440503B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8109343A IT1210639B (it) 1981-02-25 1981-02-25 Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione

Publications (2)

Publication Number Publication Date
SE8201184L SE8201184L (sv) 1982-08-26
SE440503B true SE440503B (sv) 1985-08-05

Family

ID=11128724

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8201184A SE440503B (sv) 1981-02-25 1982-02-25 3-(4-fenyl-1-piperazino-1-yl)-1,2-propandiol-3-(teofyllin-7-yl)-1-propansulfonat, forfarande for framstellning av denna samt lekemedel med antitussiv verkan

Country Status (18)

Country Link
US (1) US4372958A (no)
JP (1) JPS57188589A (no)
AT (1) AT380881B (no)
BE (1) BE892271A (no)
CA (1) CA1192549A (no)
CH (1) CH651043A5 (no)
DE (1) DE3205149A1 (no)
DK (1) DK148687C (no)
ES (1) ES8302680A1 (no)
FR (1) FR2500455A1 (no)
GB (1) GB2093445B (no)
GR (1) GR76060B (no)
IT (1) IT1210639B (no)
LU (1) LU83962A1 (no)
NL (1) NL8200746A (no)
PT (1) PT74463B (no)
SE (1) SE440503B (no)
YU (1) YU44007B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
IT1217950B (it) * 1988-06-28 1990-03-30 Dott Formenti Ind Chimica E Fa Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
DE3938123A1 (de) * 1989-11-16 1991-05-23 Diehl Gmbh & Co Treibladungsanzuender
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163649A (en) * 1964-12-29 Substituteb phenyl-piperazine
GB938646A (en) * 1961-03-16 1963-10-02 Henri Morren New piperazine derivatives
FR1384693A (fr) * 1963-10-08 1965-01-08 Electrochimie Soc Procédé de préparation d'esters méthallyliques
FR1554628A (no) * 1967-05-23 1969-01-24

Also Published As

Publication number Publication date
NL8200746A (nl) 1982-09-16
IT1210639B (it) 1989-09-14
YU44007B (en) 1990-02-28
PT74463A (en) 1982-03-01
DK79982A (da) 1982-08-26
DE3205149C2 (no) 1991-04-18
BE892271A (fr) 1982-06-16
GB2093445A (en) 1982-09-02
YU41282A (en) 1987-10-31
DE3205149A1 (de) 1982-11-11
GB2093445B (en) 1985-02-27
FR2500455A1 (fr) 1982-08-27
AT380881B (de) 1986-07-25
LU83962A1 (fr) 1982-07-08
FR2500455B1 (no) 1984-04-27
GR76060B (no) 1984-08-03
ATA59982A (de) 1985-12-15
IT8109343A0 (it) 1981-02-25
DK148687B (da) 1985-09-02
CA1192549A (en) 1985-08-27
US4372958A (en) 1983-02-08
JPS57188589A (en) 1982-11-19
SE8201184L (sv) 1982-08-26
ES509850A0 (es) 1983-02-01
PT74463B (en) 1983-08-24
JPH0333715B2 (no) 1991-05-20
ES8302680A1 (es) 1983-02-01
DK148687C (da) 1986-04-28
CH651043A5 (it) 1985-08-30

Similar Documents

Publication Publication Date Title
HU206042B (en) Process for producing pharmaceutical compositions comprising indole-3-carboxylic acid-endo-8-methyl-8-azabicyclo/3.2.1./oct-3-yl ester and/or 1,2,3-9-tetrahydro-9-methyl-3-(2-methyl-1h-imidazol-1-yl)-methyl-4h-carbazol-4-one, with an activity preventing or reducing opiate-, alcohol- and nicotine-dependence
CN102046201B (zh) 镇痛耐受性抑制剂
JPS62249923A (ja) パ−キンソン病、うつ病、ナルコレプシ−および脳器官精神症候群の抑制用薬剤およびその製造方法
IE63662B1 (en) Salts of azelastine having improved solubility
DE2827497C2 (de) Verwendung von 2-(7'-Theophyllinmethyl)-1,3-dioxolan zur Bekämpfung von bronchialen Erkrankungen
SE440503B (sv) 3-(4-fenyl-1-piperazino-1-yl)-1,2-propandiol-3-(teofyllin-7-yl)-1-propansulfonat, forfarande for framstellning av denna samt lekemedel med antitussiv verkan
RU2005135133A (ru) Фармацевтические композиции
US2891890A (en) Method of treating parkinsonism
CN105535007A (zh) 淫羊藿苷及其衍生物用于预防和治疗精神障碍的用途
US3256149A (en) Compositions comprising an alkaloid of mitragyna speciosa and methods of using same
JP2003327529A (ja) 鎮咳薬および該鎮咳薬を含有する医薬組成物
WO1994003193A1 (en) Remedy for biotoxin type bacterial intestinal infectious diseases
EP0371246A1 (en) Antiemesis ergoline derivatives
CA2154907A1 (en) Use of eliprodil and enantiomers thereof for the preparation of medicines useful for preventing peripheral neuropathies induced by anticancer agents
CA1280372C (en) Treatment of disorders of the gastro-intestinal tract
MARX et al. Effectiveness of N-allylnormorphine in the management of acute morphine poisoning
JP2004026810A (ja) 鼻炎用組成物
US3743746A (en) Process of treating peptic ulcer with a non-anticholinergic agent
Cutting Recent Drugs: A Review
Zav'ialov et al. Toxicity of single and multiple administrations of phosphorus-containing isothiuronim derivatives possessing radioprotective properties
Rees et al. Effect of nicotine, nornicotine and allylnornicotine on the diuretic response to water in rats
Thomas Loxapine oral liquid concentrate in the treatment of young adult patients with acute schizophrenic symptoms.
Baroni et al. Yellowish face mask in a child: A local side-effect of inhaled corticosteroids?
Misevic et al. The Use of Akineton for Parkinsonism
JPS5462327A (en) Remedy for dna virus infectious disease

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8201184-2

Effective date: 19920904

Format of ref document f/p: F