IT1210639B - Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione - Google Patents
Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazioneInfo
- Publication number
- IT1210639B IT1210639B IT8109343A IT934381A IT1210639B IT 1210639 B IT1210639 B IT 1210639B IT 8109343 A IT8109343 A IT 8109343A IT 934381 A IT934381 A IT 934381A IT 1210639 B IT1210639 B IT 1210639B
- Authority
- IT
- Italy
- Prior art keywords
- teofillin
- propandiol
- usable
- therapy
- product
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8109343A IT1210639B (it) | 1981-02-25 | 1981-02-25 | Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione |
GB8115803A GB2093445B (en) | 1981-02-25 | 1981-05-22 | A piperazine derivative having antitussive activity |
US06/272,281 US4372958A (en) | 1981-02-25 | 1981-06-10 | Compound having antitussive activity |
DE19823205149 DE3205149A1 (de) | 1981-02-25 | 1982-02-13 | 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-3-(theophyllin-7-yl)-propansulfonat, verfahren zu seiner herstellung und es enthaltende arzneimittel |
AT0059982A AT380881B (de) | 1981-02-25 | 1982-02-17 | Verfahren zur herstellung des neuen 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-(theophyllin-7-yl)-1-propansulfonats |
PT74463A PT74463B (en) | 1981-02-25 | 1982-02-19 | Process for the preparation of 3(4-phenyl-1-piperazinio-1-yl)- -1,2-propanediol 3(theophyllin-7-yl)-1-propanesulphonate having antitussive activity |
LU83962A LU83962A1 (fr) | 1981-02-25 | 1982-02-23 | Nouveau compose utile comme medicament antitussif et son procede de preparation |
GR67396A GR76060B (it) | 1981-02-25 | 1982-02-23 | |
NL8200746A NL8200746A (nl) | 1981-02-25 | 1982-02-24 | Verbinding met antitussive activiteit, werkwijze ter bereiding daarvan en toepassing. |
CA000397008A CA1192549A (en) | 1981-02-25 | 1982-02-24 | 3-(4-phenyl-1-piperazino-1-yl)-1,2-propane-diol 3-(theophyllin-7-yl)-1-propane sulfphonate having anti-tussive activity |
ES509850A ES509850A0 (es) | 1981-02-25 | 1982-02-24 | "un procedimiento para sintetizar 3(4-fenil-1-piperacinio-1-il)-1,2-propandiol 3(teofilin-7-il)-1-propansulfonato" |
DK79982A DK148687C (da) | 1981-02-25 | 1982-02-24 | Analogifremgangsmaade til fremstilling af 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-3-(theophyllin-7-yl)-1-propansulfonat |
YU412/82A YU44007B (en) | 1981-02-25 | 1982-02-24 | Process for obtaining 3(4-phenyl-1-piperazino-1-yl)-1,2-propandiole-3-(theophilyne-7-yl)-1-propansulphonate |
JP57027570A JPS57188589A (en) | 1981-02-25 | 1982-02-24 | 3(4-phenyl-1-piperazino-1-yl)-1,2-propanediol- 3-(theophyllin-7-yl)-1-propane sulfonate, manufacture and antitussive medicine containing same |
SE8201184A SE440503B (sv) | 1981-02-25 | 1982-02-25 | 3-(4-fenyl-1-piperazino-1-yl)-1,2-propandiol-3-(teofyllin-7-yl)-1-propansulfonat, forfarande for framstellning av denna samt lekemedel med antitussiv verkan |
BE0/207403A BE892271A (fr) | 1981-02-25 | 1982-02-25 | Nouveau compose utile comme medicament antitussif et son procede de preparation |
CH1167/82A CH651043A5 (it) | 1981-02-25 | 1982-02-25 | 3(4-fenil-1-piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1-propansolfonato e relativo procedimento di fabbricazione e farmaco comprendente questo composto. |
FR8203164A FR2500455A1 (fr) | 1981-02-25 | 1982-02-25 | Derive de 1,2-propanediol possedant une activite antitussive et son procede pour sa preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8109343A IT1210639B (it) | 1981-02-25 | 1981-02-25 | Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8109343A0 IT8109343A0 (it) | 1981-02-25 |
IT1210639B true IT1210639B (it) | 1989-09-14 |
Family
ID=11128724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8109343A IT1210639B (it) | 1981-02-25 | 1981-02-25 | Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione |
Country Status (18)
Country | Link |
---|---|
US (1) | US4372958A (it) |
JP (1) | JPS57188589A (it) |
AT (1) | AT380881B (it) |
BE (1) | BE892271A (it) |
CA (1) | CA1192549A (it) |
CH (1) | CH651043A5 (it) |
DE (1) | DE3205149A1 (it) |
DK (1) | DK148687C (it) |
ES (1) | ES509850A0 (it) |
FR (1) | FR2500455A1 (it) |
GB (1) | GB2093445B (it) |
GR (1) | GR76060B (it) |
IT (1) | IT1210639B (it) |
LU (1) | LU83962A1 (it) |
NL (1) | NL8200746A (it) |
PT (1) | PT74463B (it) |
SE (1) | SE440503B (it) |
YU (1) | YU44007B (it) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1203721B (it) * | 1983-12-29 | 1989-02-23 | Dompe Farmaceutici Spa | Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono |
IT1217950B (it) * | 1988-06-28 | 1990-03-30 | Dott Formenti Ind Chimica E Fa | Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo |
IT1231158B (it) * | 1989-07-20 | 1991-11-19 | Dompe Farmaceutici Spa | Procedimento per la risoluzione ottica della dropropizina. |
DE3938123A1 (de) * | 1989-11-16 | 1991-05-23 | Diehl Gmbh & Co | Treibladungsanzuender |
IT1318651B1 (it) * | 2000-07-28 | 2003-08-27 | Dompe Spa | Sintesi di (+-)1,3-diossolani e loro risoluzione ottica. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3163649A (en) * | 1964-12-29 | Substituteb phenyl-piperazine | ||
GB938646A (en) * | 1961-03-16 | 1963-10-02 | Henri Morren | New piperazine derivatives |
FR1384693A (fr) * | 1963-10-08 | 1965-01-08 | Electrochimie Soc | Procédé de préparation d'esters méthallyliques |
FR1554628A (it) * | 1967-05-23 | 1969-01-24 |
-
1981
- 1981-02-25 IT IT8109343A patent/IT1210639B/it active
- 1981-05-22 GB GB8115803A patent/GB2093445B/en not_active Expired
- 1981-06-10 US US06/272,281 patent/US4372958A/en not_active Expired - Fee Related
-
1982
- 1982-02-13 DE DE19823205149 patent/DE3205149A1/de active Granted
- 1982-02-17 AT AT0059982A patent/AT380881B/de not_active IP Right Cessation
- 1982-02-19 PT PT74463A patent/PT74463B/pt unknown
- 1982-02-23 LU LU83962A patent/LU83962A1/fr unknown
- 1982-02-23 GR GR67396A patent/GR76060B/el unknown
- 1982-02-24 JP JP57027570A patent/JPS57188589A/ja active Granted
- 1982-02-24 YU YU412/82A patent/YU44007B/xx unknown
- 1982-02-24 DK DK79982A patent/DK148687C/da active
- 1982-02-24 CA CA000397008A patent/CA1192549A/en not_active Expired
- 1982-02-24 ES ES509850A patent/ES509850A0/es active Granted
- 1982-02-24 NL NL8200746A patent/NL8200746A/nl not_active Application Discontinuation
- 1982-02-25 FR FR8203164A patent/FR2500455A1/fr active Granted
- 1982-02-25 BE BE0/207403A patent/BE892271A/fr not_active IP Right Cessation
- 1982-02-25 SE SE8201184A patent/SE440503B/sv not_active IP Right Cessation
- 1982-02-25 CH CH1167/82A patent/CH651043A5/it not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2500455B1 (it) | 1984-04-27 |
BE892271A (fr) | 1982-06-16 |
DE3205149C2 (it) | 1991-04-18 |
FR2500455A1 (fr) | 1982-08-27 |
GB2093445A (en) | 1982-09-02 |
GB2093445B (en) | 1985-02-27 |
JPH0333715B2 (it) | 1991-05-20 |
YU44007B (en) | 1990-02-28 |
DK79982A (da) | 1982-08-26 |
LU83962A1 (fr) | 1982-07-08 |
YU41282A (en) | 1987-10-31 |
PT74463A (en) | 1982-03-01 |
CA1192549A (en) | 1985-08-27 |
SE8201184L (sv) | 1982-08-26 |
GR76060B (it) | 1984-08-03 |
DE3205149A1 (de) | 1982-11-11 |
DK148687B (da) | 1985-09-02 |
PT74463B (en) | 1983-08-24 |
AT380881B (de) | 1986-07-25 |
NL8200746A (nl) | 1982-09-16 |
JPS57188589A (en) | 1982-11-19 |
US4372958A (en) | 1983-02-08 |
CH651043A5 (it) | 1985-08-30 |
IT8109343A0 (it) | 1981-02-25 |
ES8302680A1 (es) | 1983-02-01 |
ES509850A0 (es) | 1983-02-01 |
DK148687C (da) | 1986-04-28 |
ATA59982A (de) | 1985-12-15 |
SE440503B (sv) | 1985-08-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT7923395A0 (it) | N-aril-ossazolidinoni, -ossazolidintioni, -pirrolidinoni, -pirrolidine e -tiazolidinoni, loro procedimento di preparazione eloro applicazione in terapia. | |
BR8207762A (pt) | Processo terapeutico e processo para fabricar composicoes destinadas a serem usadas no mesmo | |
TR23322A (tr) | Alfa-aril-alfa-feniletil-1h-1,2,4-triazol-1-propannitriller | |
IT1219191B (it) | Macchina elettrica e relativo procedimento di fabbricazione | |
DE69015788D1 (de) | Thermistor und dessen herstellung. | |
IT8422142A0 (it) | Procedimento di preparazione. cefem composti ad azione farmaceutica e relativo | |
NO882858D0 (no) | Silikapartikler, fremstilling og anvendelse derav. | |
IT1191152B (it) | Derivati aminoalcossi aromatici,loro procedimento di preparazione e loro applicazione in terapia | |
IT1214648B (it) | 8 alfa-acilamminoergoline,loro preparazione e loro impiego come medicamenti | |
DK293783A (da) | Pigmentroedt 53.1 i dets krystallografiske beta-modifikation, dets fremstilling og anvendelse | |
IT1141966B (it) | Tiol-esteri,loro preparazione e lo impiego in sintesi | |
IT1210639B (it) | Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione | |
NO901345D0 (no) | Bindemiddel for anvendelse i stoeperier, samt fremgangsmaate for fremstilling av stoepekjerner og -former. | |
EP0034249A3 (en) | New naphthimidazole and naphthoxazole derivatives, their preparation, and their use in pharmaceuticals | |
IT8321465A0 (it) | Impiego di 1,4-diidropiridine in prodotti antiarterioclerosi e loro preparazione. | |
ZA828743B (en) | (2)-2-(1-(2,6-dichlorophenoxy)-ethyl)-1,3-diazacyclopent-2-ene,the production thereof and the uste thereof in pharmaceutical preparations | |
IT1167276B (it) | Derivati bezilidenici solforati, loro preparazione e loro applicazione in terapia | |
IT1153062B (it) | Derivati benzilidenici, loro preparazione e loro applicazione in terapia | |
DE3476412D1 (en) | Pigment preparations, their manufacturing process and their use | |
TR22481A (tr) | N-formil fosfonamidotioatlar,hazirlanmalari icin yoenetmenler ve bunlarin bitki korunmasinda kullanilmalari | |
IT8119666A0 (it) | Derivati benzilidenici,loro preparazione e loro applicazioni in terapia | |
IL60332A (en) | 3-amino-5-(4-pyridyl)-1,2,4-triazoles and pharmaceutical compositions comprising them | |
ES545095A0 (es) | Perfeccionamientos en los obuses prefragmentados | |
IT8646855A0 (it) | Prodotto dolciario e relativo procedimento di realizzazione | |
IT8220819A0 (it) | Derivati diossazabiciclici,loro procedimento di preparazione e loro applicazione in terapia. |