SE437265B - Forfarande for framstellning av 1-fenyl-2,3,4,5-tetrahydro-1h-3-bensazepiner och farmaceutiskt godtagbara syraadditionssalter derav - Google Patents

Forfarande for framstellning av 1-fenyl-2,3,4,5-tetrahydro-1h-3-bensazepiner och farmaceutiskt godtagbara syraadditionssalter derav

Info

Publication number
SE437265B
SE437265B SE7800455A SE7800455A SE437265B SE 437265 B SE437265 B SE 437265B SE 7800455 A SE7800455 A SE 7800455A SE 7800455 A SE7800455 A SE 7800455A SE 437265 B SE437265 B SE 437265B
Authority
SE
Sweden
Prior art keywords
phenyl
tetrahydro
acid addition
pharmaceutically acceptable
acceptable acid
Prior art date
Application number
SE7800455A
Other languages
English (en)
Swedish (sv)
Other versions
SE7800455L (sv
Inventor
K G Holden
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of SE7800455L publication Critical patent/SE7800455L/xx
Publication of SE437265B publication Critical patent/SE437265B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/04Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
SE7800455A 1977-01-19 1978-01-16 Forfarande for framstellning av 1-fenyl-2,3,4,5-tetrahydro-1h-3-bensazepiner och farmaceutiskt godtagbara syraadditionssalter derav SE437265B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76050077A 1977-01-19 1977-01-19

Publications (2)

Publication Number Publication Date
SE7800455L SE7800455L (sv) 1978-07-20
SE437265B true SE437265B (sv) 1985-02-18

Family

ID=25059291

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7800455A SE437265B (sv) 1977-01-19 1978-01-16 Forfarande for framstellning av 1-fenyl-2,3,4,5-tetrahydro-1h-3-bensazepiner och farmaceutiskt godtagbara syraadditionssalter derav

Country Status (15)

Country Link
JP (1) JPS6040423B2 (fr)
AU (1) AU510459B2 (fr)
BE (1) BE862878A (fr)
CA (1) CA1090334A (fr)
CH (2) CH642634A5 (fr)
DE (1) DE2802086A1 (fr)
DK (1) DK19978A (fr)
FR (2) FR2378017A1 (fr)
GB (2) GB1597912A (fr)
HU (1) HU175836B (fr)
IE (1) IE46761B1 (fr)
LU (1) LU78873A1 (fr)
NL (1) NL7800637A (fr)
SE (1) SE437265B (fr)
ZA (1) ZA777444B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4251525A (en) * 1979-05-25 1981-02-17 Smithkline Corporation 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
EP0022330B1 (fr) * 1979-07-10 1983-12-21 Smithkline Beckman Corporation Compositions synergiques anti-hypertensives
WO2005035504A2 (fr) * 2003-05-22 2005-04-21 Schering Corporation Antagonistes selectifs des recepteurs d1/d5 utilises dans le traitement de l'obesite et des troubles du systeme nerveux central

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH555831A (de) * 1967-02-17 1974-11-15 Scherico Ltd Verfahren zur herstellung von neuen benzazepinen.
US3609139A (en) * 1969-04-01 1971-09-28 Sandoz Ag Substituted dibenzdiazonines
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them

Also Published As

Publication number Publication date
FR2378017A1 (fr) 1978-08-18
AU3246578A (en) 1979-07-26
BE862878A (fr) 1978-07-13
FR2384759B1 (fr) 1980-07-18
CH642634A5 (en) 1984-04-30
IE780111L (en) 1978-07-19
LU78873A1 (fr) 1978-06-09
CA1090334A (fr) 1980-11-25
NL7800637A (nl) 1978-07-21
JPS5390281A (en) 1978-08-08
GB1597912A (en) 1981-09-16
AU510459B2 (en) 1980-06-26
IE46761B1 (en) 1983-09-21
CH640228A5 (en) 1983-12-30
ZA777444B (en) 1978-10-25
FR2378017B1 (fr) 1981-07-10
GB1597911A (en) 1981-09-16
HU175836B (hu) 1980-10-28
FR2384759A1 (fr) 1978-10-20
JPS6040423B2 (ja) 1985-09-11
SE7800455L (sv) 1978-07-20
DK19978A (da) 1978-07-20
DE2802086A1 (de) 1978-07-20

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