CA1090334A - Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepines a action dopaminergique - Google Patents
Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepines a action dopaminergiqueInfo
- Publication number
- CA1090334A CA1090334A CA294,973A CA294973A CA1090334A CA 1090334 A CA1090334 A CA 1090334A CA 294973 A CA294973 A CA 294973A CA 1090334 A CA1090334 A CA 1090334A
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- tetrahydro
- methylthio
- phenyl
- carbons
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76050077A | 1977-01-19 | 1977-01-19 | |
US760,500 | 1977-01-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1090334A true CA1090334A (fr) | 1980-11-25 |
Family
ID=25059291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA294,973A Expired CA1090334A (fr) | 1977-01-19 | 1978-01-16 | Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepines a action dopaminergique |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS6040423B2 (fr) |
AU (1) | AU510459B2 (fr) |
BE (1) | BE862878A (fr) |
CA (1) | CA1090334A (fr) |
CH (2) | CH642634A5 (fr) |
DE (1) | DE2802086A1 (fr) |
DK (1) | DK19978A (fr) |
FR (2) | FR2378017A1 (fr) |
GB (2) | GB1597911A (fr) |
HU (1) | HU175836B (fr) |
IE (1) | IE46761B1 (fr) |
LU (1) | LU78873A1 (fr) |
NL (1) | NL7800637A (fr) |
SE (1) | SE437265B (fr) |
ZA (1) | ZA777444B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5481290A (en) * | 1977-11-17 | 1979-06-28 | Smithkline Corp | Benzazepin compound |
US4171359A (en) * | 1978-04-12 | 1979-10-16 | Smithkline Corporation | Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
US4251525A (en) * | 1979-05-25 | 1981-02-17 | Smithkline Corporation | 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives |
DE3065940D1 (en) * | 1979-07-10 | 1984-01-26 | Smithkline Beckman Corp | Synergistic antihypertensive compositions |
JP2006526021A (ja) * | 2003-05-22 | 2006-11-16 | シェーリング コーポレイション | 肥満およびcns障害を治療する選択的d1/d5レセプタアンタゴニストとしての5h−ベンゾ[d]ナフト[2,1−b]アゼピン誘導体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH555831A (de) * | 1967-02-17 | 1974-11-15 | Scherico Ltd | Verfahren zur herstellung von neuen benzazepinen. |
US3609139A (en) * | 1969-04-01 | 1971-09-28 | Sandoz Ag | Substituted dibenzdiazonines |
US4011319A (en) * | 1975-07-02 | 1977-03-08 | Smithkline Corporation | Pharmaceutical compositions and methods involving benzazepine derivatives |
GB1561305A (en) * | 1975-07-02 | 1980-02-20 | Smithkline Corp | Benzazepine derivatives and pharmeceutical compositions containing them |
-
1977
- 1977-12-14 ZA ZA00777444A patent/ZA777444B/xx unknown
-
1978
- 1978-01-10 GB GB953/78A patent/GB1597911A/en not_active Expired
- 1978-01-10 GB GB20952/80A patent/GB1597912A/en not_active Expired
- 1978-01-13 FR FR7800998A patent/FR2378017A1/fr active Granted
- 1978-01-13 BE BE184290A patent/BE862878A/fr not_active IP Right Cessation
- 1978-01-16 LU LU78873A patent/LU78873A1/fr unknown
- 1978-01-16 SE SE7800455A patent/SE437265B/sv not_active IP Right Cessation
- 1978-01-16 AU AU32465/78A patent/AU510459B2/en not_active Expired
- 1978-01-16 DK DK19978A patent/DK19978A/da not_active Application Discontinuation
- 1978-01-16 CA CA294,973A patent/CA1090334A/fr not_active Expired
- 1978-01-18 DE DE19782802086 patent/DE2802086A1/de not_active Withdrawn
- 1978-01-18 HU HU78SI1612A patent/HU175836B/hu unknown
- 1978-01-18 CH CH52578A patent/CH642634A5/de not_active IP Right Cessation
- 1978-01-18 IE IE111/78A patent/IE46761B1/en unknown
- 1978-01-18 NL NL7800637A patent/NL7800637A/xx not_active Application Discontinuation
- 1978-01-18 JP JP53004769A patent/JPS6040423B2/ja not_active Expired
- 1978-06-02 FR FR7816583A patent/FR2384759A1/fr active Granted
-
1982
- 1982-06-09 CH CH357382A patent/CH640228A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE7800455L (sv) | 1978-07-20 |
JPS6040423B2 (ja) | 1985-09-11 |
IE780111L (en) | 1978-07-19 |
AU510459B2 (en) | 1980-06-26 |
IE46761B1 (en) | 1983-09-21 |
HU175836B (hu) | 1980-10-28 |
DE2802086A1 (de) | 1978-07-20 |
GB1597912A (en) | 1981-09-16 |
SE437265B (sv) | 1985-02-18 |
ZA777444B (en) | 1978-10-25 |
FR2378017A1 (fr) | 1978-08-18 |
GB1597911A (en) | 1981-09-16 |
FR2378017B1 (fr) | 1981-07-10 |
BE862878A (fr) | 1978-07-13 |
CH640228A5 (en) | 1983-12-30 |
LU78873A1 (fr) | 1978-06-09 |
FR2384759B1 (fr) | 1980-07-18 |
FR2384759A1 (fr) | 1978-10-20 |
DK19978A (da) | 1978-07-20 |
JPS5390281A (en) | 1978-08-08 |
NL7800637A (nl) | 1978-07-21 |
CH642634A5 (en) | 1984-04-30 |
AU3246578A (en) | 1979-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4359464A (en) | 3-Furylmethyl-6-halo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines and antihypertensive use thereof | |
US4255422A (en) | 6-Halo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | |
US4160765A (en) | Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds | |
US4108989A (en) | 2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diones | |
US4086350A (en) | Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms | |
JPS6033409B2 (ja) | ベンズアゼピン誘導体を含む医薬組成物 | |
US4104379A (en) | Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds | |
CA1090334A (fr) | Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepines a action dopaminergique | |
CA1079639A (fr) | Derives de la 3-benzazepine | |
US4206210A (en) | Alkylthio-7,8-dihdroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines having dopaminergic activity | |
EP0004794B1 (fr) | Benzazépines substituées, procédés pour leur préparation et compositions pharmaceutiques les contenant | |
HU201020B (en) | Process for producine new naphthalene derivatives and pharmaceutical compositions comprising same | |
Chupp et al. | Heterocycles from substituted amides. VI. A new carbostyril synthesis from alpha‐substituted acetamides and the vilsmeier reagent | |
EP0233049A1 (fr) | Hexahydro-2,3,4,8,9,9a aryl-4 1H-indéno[1,7-cd]azépines | |
CA1102807A (fr) | Traduction non-disponible | |
EP0002327B1 (fr) | 6-Alcoyl inférieur-7,8- dihydroxy-1-phényl-2,3,4,5-tétrahydro-1H-3- benzazépines, leurs méthodes de préparation et intermédiaires | |
EP0127423B1 (fr) | 1-(4'-Alcoyl branché sulfonylphényl)-6-chloro-7,8-dihydroxy-2,3,4,5-tétrahydro-1H-3-benzazépines | |
US4255445A (en) | 8-Hydroxy-6,7-(2-methyl-2,3-dihydrofuro)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | |
US4352754A (en) | 3-Thienylmethyl-6-halo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | |
US4165372A (en) | 6-Carboxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds and use as dopaminergic agents | |
US4285938A (en) | 7,8-Dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives | |
US4172890A (en) | 2,3,4,5-Tetrahydro-1H-3-benzazepine-7,8-diones | |
KR830001667B1 (ko) | 페닐 퀴놀리지딘의 제조방법 | |
EP0246633B1 (fr) | Dérivés de la trans-benzopyran-[4,3-b]-1,4-oxazine | |
KR810000801B1 (ko) | 2-테트라 하이드로 푸르푸릴-6,7-벤조모르판류의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |