SE435385B - Analogiforfarande for framstellning av 3,4-dihydropyrimido(1,2-a)bensimidazolderivat - Google Patents

Analogiforfarande for framstellning av 3,4-dihydropyrimido(1,2-a)bensimidazolderivat

Info

Publication number
SE435385B
SE435385B SE7713958A SE7713958A SE435385B SE 435385 B SE435385 B SE 435385B SE 7713958 A SE7713958 A SE 7713958A SE 7713958 A SE7713958 A SE 7713958A SE 435385 B SE435385 B SE 435385B
Authority
SE
Sweden
Prior art keywords
radical
formula
hydrogen
compound
benzoyl
Prior art date
Application number
SE7713958A
Other languages
English (en)
Swedish (sv)
Other versions
SE7713958L (sv
Inventor
S D Mills
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB51426/76A external-priority patent/GB1585965A/en
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of SE7713958L publication Critical patent/SE7713958L/xx
Publication of SE435385B publication Critical patent/SE435385B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7713958A 1976-12-09 1977-12-08 Analogiforfarande for framstellning av 3,4-dihydropyrimido(1,2-a)bensimidazolderivat SE435385B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB51426/76A GB1585965A (en) 1976-12-09 1976-12-09 3,4-dihydropyrimido (1,2 - )benzimidazol - 2(1h) - ones
GB3334177 1977-08-09

Publications (2)

Publication Number Publication Date
SE7713958L SE7713958L (sv) 1978-06-10
SE435385B true SE435385B (sv) 1984-09-24

Family

ID=26261828

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7713958A SE435385B (sv) 1976-12-09 1977-12-08 Analogiforfarande for framstellning av 3,4-dihydropyrimido(1,2-a)bensimidazolderivat

Country Status (23)

Country Link
US (1) US4167569A (de)
JP (1) JPS5390296A (de)
AT (1) AT359068B (de)
AU (1) AU514427B2 (de)
CA (1) CA1086727A (de)
CH (1) CH633291A5 (de)
CS (1) CS199696B2 (de)
DD (1) DD133330A5 (de)
DE (1) DE2754930A1 (de)
ES (1) ES464862A1 (de)
FI (1) FI63577C (de)
FR (1) FR2373543A1 (de)
GR (1) GR65298B (de)
HU (1) HU176540B (de)
IE (1) IE45924B1 (de)
IL (1) IL53507A (de)
IT (1) IT1143729B (de)
NL (1) NL7713658A (de)
NO (1) NO774216L (de)
NZ (1) NZ185823A (de)
PL (1) PL107142B1 (de)
SE (1) SE435385B (de)
SU (1) SU843751A3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1157858A (en) 1979-12-03 1983-11-29 Ikuo Ueda Quinazoline derivatives
IE51802B1 (en) * 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
DE3208218A1 (de) * 1982-03-06 1983-09-08 Basf Ag, 6700 Ludwigshafen Isoindolinfarbstoffe und deren verwendung
RU2453312C1 (ru) * 2010-11-10 2012-06-20 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" Средство, проявляющее антиагрегантную и антитромбогенную активности
MY167785A (en) 2012-06-27 2018-09-25 4Sg Ag Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and cns disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468888A (en) * 1967-04-11 1969-09-23 Smithkline Corp 2-substituted pyrimido(1,2-a) benzimidazoles
US3988340A (en) * 1975-01-23 1976-10-26 Bristol-Myers Company 6-Alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]quinazolin-2-ones
US4072679A (en) * 1976-06-15 1978-02-07 E. R. Squibb & Sons, Inc. 1,4- AND 4,10-DIHYDRO-4-OXO-PYRIMIDO (1,2-A)-benzimidazole-3-carboxylic acids, esters and amides

Also Published As

Publication number Publication date
IE45924L (en) 1978-06-09
FR2373543B1 (de) 1980-05-16
CS199696B2 (en) 1980-07-31
FR2373543A1 (fr) 1978-07-07
IE45924B1 (en) 1982-12-29
SU843751A3 (ru) 1981-06-30
DE2754930A1 (de) 1978-06-15
AU514427B2 (en) 1981-02-12
NO774216L (no) 1978-06-12
GR65298B (en) 1980-08-01
AT359068B (de) 1980-10-27
FI63577B (fi) 1983-03-31
HU176540B (en) 1981-03-28
US4167569A (en) 1979-09-11
DD133330A5 (de) 1978-12-27
CA1086727A (en) 1980-09-30
IL53507A0 (en) 1978-03-10
IL53507A (en) 1981-07-31
SE7713958L (sv) 1978-06-10
IT1143729B (it) 1986-10-22
ATA883677A (de) 1980-03-15
JPS5390296A (en) 1978-08-08
NZ185823A (en) 1980-08-26
CH633291A5 (de) 1982-11-30
PL202753A1 (pl) 1978-10-09
FI773724A (fi) 1978-06-10
AU3112177A (en) 1979-06-07
FI63577C (fi) 1983-07-11
ES464862A1 (es) 1979-01-01
PL107142B1 (pl) 1980-01-31
NL7713658A (nl) 1978-06-13

Similar Documents

Publication Publication Date Title
USRE31617E (en) Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
FI94627C (fi) Uusia isoindolonijohdannaisia niiden valmistus ja käyttö
FI61696B (fi) Foerfarande foer framstaellning av vasodilatoriska 1,4-dihydropyridinderivat
JPS62201882A (ja) イソフラボン誘導体
SK33995A3 (en) Imidazodiazepines
FI89600C (fi) Foerfarande foer framstaellning av terapeutiskt aktivt imidazo/1,2-b/pyridazin-2-ylkarbamatderivat
FR2598709A1 (fr) Derives de l'acide quinoleinecarboxylique
US4772696A (en) Oxadiazolyl imidazobenzodiazepine process
SE435385B (sv) Analogiforfarande for framstellning av 3,4-dihydropyrimido(1,2-a)bensimidazolderivat
NO873108L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 1,4-benzodiazepiner.
CA3176493A1 (en) Cbp/ep300 inhibitor and use thereof
US4495187A (en) Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents
CS114291A3 (en) Benzothieno-[2,3-b] pyrazine-2,3-(1h,4h) diones, processes for their preparation and a pharmaceutical comprising them
US3636041A (en) 4 5-dihydro-7h-thieno(2 3-c)thiopyrans
US4547501A (en) Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents
RU2631100C1 (ru) Новые производные гетероаренантрацен-2-карбоксамидов, ингибирующие опухолевый рост
US4372956A (en) 5, 10-Dihydroimidazo[2,1-b]quinazolines and pharmaceutical compositions containing them
IE903083A1 (en) Tetracyclic Imidazoquinazoline Derivatives, Preparation and Pharmaceutical Compositions
GB1585965A (en) 3,4-dihydropyrimido (1,2 - )benzimidazol - 2(1h) - ones
US3822259A (en) 7-phenyl-1h(1,3)-oxazino(3,2-a)(1,4)benzodiazepine-1,3(2h)-diones
Aly et al. Synthesis of some fused heterocycles containing 2, 5-disubstituted-1, 3, 4-thiadiazoles
FI88036B (fi) Foerfarande foer framstaellning av saosom bensodiazepinreceptoragonister/antagonister anvaendbara 2-aryl-tetrahydro(pyrido- och pyrrolo)/e//1,2,4/triazolo/1,5-c/pyrimidoner
US5097036A (en) Substituted 7-oxomitosanes
JPS6228145B2 (de)
CH634845A5 (en) Pharmaceutically useful pyrimido(1,2-a)benzimidazole derivatives and corresponding preparations.