SE0301569D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SE0301569D0 SE0301569D0 SE0301569A SE0301569A SE0301569D0 SE 0301569 D0 SE0301569 D0 SE 0301569D0 SE 0301569 A SE0301569 A SE 0301569A SE 0301569 A SE0301569 A SE 0301569A SE 0301569 D0 SE0301569 D0 SE 0301569D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- novel
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (66)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301569A SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Novel compounds |
SE0302305A SE0302305D0 (sv) | 2003-05-27 | 2003-08-27 | Novel Compounds |
TW093114113A TWI328004B (en) | 2003-05-27 | 2004-05-19 | Substituted indoles and use thereof |
TW099109193A TW201024261A (en) | 2003-05-27 | 2004-05-19 | Substituted indoles and preparation and use thereof |
ARP040101792A AR044552A1 (es) | 2003-05-27 | 2004-05-24 | Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios |
DE602004020072T DE602004020072D1 (de) | 2003-05-27 | 2004-05-25 | 1,2,3,4-tetrasubstituiertes indol zur behandlung von atemwegserkrankungen |
BRPI0410711A BRPI0410711B8 (pt) | 2003-05-27 | 2004-05-25 | ácido 4-(acetilamina)-3-[(4-clorofenil)tio]-2-metil-1h-indol-1-acético |
CN2004800146027A CN1795174B (zh) | 2003-05-27 | 2004-05-25 | 取代的3-硫吲哚 |
PT04734774T PT1656346E (pt) | 2003-05-27 | 2004-05-25 | Indole 1,2,3,4-tetrassubstituído para o tratamento de doenças respiratórias |
ES04734774T ES2322650T3 (es) | 2003-05-27 | 2004-05-25 | Indol 1,2,3,4-tetrasustituido para el tratamiento de enfermedades respiratorias. |
SI200431120T SI1656346T1 (sl) | 2003-05-27 | 2004-05-25 | 1,2,3,4-tetrasubstituiran indol za zdravljenje respiratornih bolezni |
AT10180348T ATE552243T1 (de) | 2003-05-27 | 2004-05-25 | 4-(acetylamino)-3-ä(4-chlorophenyl)thioü-2-meth l-1h-indole-1-essigsäure-ethyl-ester zwischenverbindung |
ES08165755T ES2361485T3 (es) | 2003-05-27 | 2004-05-25 | Uso de derivados de ácido 3-feniltio-1h-indol-acético como moduladores de la actividad del receptor crth2. |
EP08165755A EP2025670B1 (en) | 2003-05-27 | 2004-05-25 | Use of 3-phenylthio-1H-indole-1-acetic acid derivatives as modulators of CRTh2 receptor activity |
UAA200511010A UA84701C2 (ru) | 2003-05-27 | 2004-05-25 | Замещенные индолы, способ их получения, их использования |
DE602004031894T DE602004031894D1 (de) | 2003-05-27 | 2004-05-25 | Verwendung von 3-Phenylthio-1H-indol-1-essigsäure-Derivate als Modulatoren der CRTh2-Rezeptor-Aktivität |
PT08165755T PT2025670E (pt) | 2003-05-27 | 2004-05-25 | Utiliza??o de derivados do ?cido 3-feniltio-1h-indole-1-ac?tico como moduladores da actividade dos receptores crth2 |
AT04734774T ATE425965T1 (de) | 2003-05-27 | 2004-05-25 | 1,2,3,4-tetrasubstituiertes indol zur behandlung von atemwegserkrankungen |
AT08165755T ATE502010T1 (de) | 2003-05-27 | 2004-05-25 | Verwendung von 3-phenylthio-1h-indol-1-essigsäure-derivate als modulatoren der crth2-rezeptor- aktivität |
PL04734774T PL1656346T3 (pl) | 2003-05-27 | 2004-05-25 | 1,2,3,4-Tetrapodstawiony indol do leczenia chorób dróg oddechowych |
ES10180348T ES2382606T3 (es) | 2003-05-27 | 2004-05-25 | Compuesto intermedio éster etílico del ácido 4-(acetilamino)-3-[(4-clorofenil)tio]-2-metil-1H-indol-acético |
DK04734774T DK1656346T3 (da) | 2003-05-27 | 2004-05-25 | 1,2,3,4-tetrasubstituerede indol til behandling af luftvejssygdomme |
CA2526866A CA2526866C (en) | 2003-05-27 | 2004-05-25 | Substituted 3-sulfur indoles for treating a disease mediated by crth2 |
SI200431874T SI2281815T1 (sl) | 2003-05-27 | 2004-05-25 | Vmesna spojina etil estra 4-(acetilamino)-3-((4-klorofenil)tio)-2-metil-1H-indol-1-ocetne kisline |
EP10180348A EP2281815B1 (en) | 2003-05-27 | 2004-05-25 | 4-(Acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid ethyl ester intermediate compound |
DK10180348.4T DK2281815T3 (da) | 2003-05-27 | 2004-05-25 | 4-(Acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid ethyl ester intermediate compound |
KR1020057022513A KR101067586B1 (ko) | 2003-05-27 | 2004-05-25 | 신규한 치환된 3-황 인돌 |
RU2005137403/04A RU2361860C2 (ru) | 2003-05-27 | 2004-05-25 | Новые замещенные 3-сера-индолы |
PCT/SE2004/000808 WO2004106302A1 (en) | 2003-05-27 | 2004-05-25 | Novel substituted 3-sulfur indoles |
NZ543722A NZ543722A (en) | 2003-05-27 | 2004-05-25 | Novel substituted 3-sulfur indoles |
KR1020117009788A KR101067535B1 (ko) | 2003-05-27 | 2004-05-25 | 신규한 치환된 3-황 인돌 |
PL10180348T PL2281815T3 (pl) | 2003-05-27 | 2004-05-25 | Związek pośredni, ester etylowy kwasu 4-(acetyloamino)-3-[(4-chlorofenylo}tio]-2-metylo-1H-indolooctowego |
MXPA05012680A MXPA05012680A (es) | 2003-05-27 | 2004-05-25 | Indoles novedosos de 3-azufre sustituidos. |
JP2006532212A JP4541361B2 (ja) | 2003-05-27 | 2004-05-25 | 新規3位硫黄置換インドール |
PL08165755T PL2025670T3 (pl) | 2003-05-27 | 2004-05-25 | Zastosowanie pochodnych kwasu 3-fenylotio-1H-indolo-1-octowego jako modulatorów aktywności receptora CRTh2 |
AU2004242624A AU2004242624B2 (en) | 2003-05-27 | 2004-05-25 | Novel substituted 3-sulfur indoles |
KR1020117009790A KR20110050754A (ko) | 2003-05-27 | 2004-05-25 | 신규한 치환된 3-황 인돌 |
SI200431669T SI2025670T1 (sl) | 2003-05-27 | 2004-05-25 | Uporaba derivatov 3-feniltio-1H-indol-1-ocetne kisline kot modulatorjev aktivnosti CRTh2 receptorja |
PT10180348T PT2281815E (pt) | 2003-05-27 | 2004-05-25 | Composto intermediário de éster etílico do ácido 4-(acetilamino)-3-[(4-clorofenil)tio]-2-metil-1h-indole- 1-acético |
US10/558,228 US7687535B2 (en) | 2003-05-27 | 2004-05-25 | Substituted 3-sulfur indoles |
MYPI20041992A MY144483A (en) | 2003-05-27 | 2004-05-25 | 1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases |
CN2011102633202A CN102391171A (zh) | 2003-05-27 | 2004-05-25 | 新型取代的3-硫吲哚 |
DK08165755.3T DK2025670T3 (da) | 2003-05-27 | 2004-05-25 | Anvendelse af 3-phenylthio-1H-indol-1-eddikesyre-derivater som modulatorer af CRTh2-receptor aktivitet |
EP04734774A EP1656346B1 (en) | 2003-05-27 | 2004-05-25 | 1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases |
IL171928A IL171928A (en) | 2003-05-27 | 2005-11-14 | Compounds of 4 - (acetylamino) - 3 - [(4 - chlorophenyl) thio] - 2 - methyl - 1H - indole - 1 - acetic acid, salts and their solvates, and their uses in the preparation of medicine |
CO05118882A CO5630030A2 (es) | 2003-05-27 | 2005-11-23 | Acido 4-(acetilamino)-3-{(4-clorofenil)tio}-2-metil-1h-indol-1-acetico y composicion farmaceutica que lo contiene |
ZA200509598A ZA200509598B (en) | 2003-05-27 | 2005-11-28 | Novel substituted 3-sulfur indoles |
IS8189A IS2722B (is) | 2003-05-27 | 2005-12-20 | 1, 2, 3, 4- Tetrasetin indól til meðhöndlunar á öndunarfærasjúkdómum |
NO20056130A NO20056130L (no) | 2003-05-27 | 2005-12-22 | Nye substituerte 3-svovelindoler |
HK06111158.9A HK1090635A1 (en) | 2003-05-27 | 2006-10-11 | Substituted 3-sulfur indoles |
IL194872A IL194872A0 (en) | 2003-05-27 | 2008-10-23 | Novel substituted 3-sulfur indoles |
US12/397,618 US20090163518A1 (en) | 2003-05-27 | 2009-03-04 | Novel Compounds |
HR20090281T HRP20090281T1 (en) | 2003-05-27 | 2009-05-15 | 1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases |
CY20091100564T CY1109104T1 (el) | 2003-05-27 | 2009-05-28 | 1,2,3,4 τετρα-υποκατεστημενη ινδολη για την αντιμετωπιση ασθενειων του αναπνευστικου |
HK11107570.0A HK1149563A1 (xx) | 2003-05-27 | 2009-06-30 | |
HK09105852.7A HK1126773A1 (xx) | 2003-05-27 | 2009-06-30 | |
JP2010082748A JP2010155862A (ja) | 2003-05-27 | 2010-03-31 | 新規3位硫黄置換インドール |
IS8920A IS8920A (is) | 2003-05-27 | 2010-08-09 | 3-(Fenýl eða kínólyl)þíó- 1H-idnól-1-ediksýru afleður sem mótarar á virkni CRTh2 vitaka. |
US13/047,280 US20110263614A1 (en) | 2003-05-27 | 2011-03-14 | Novel compounds |
IL212265A IL212265A0 (en) | 2003-05-27 | 2011-04-11 | Novel compounds |
IL212371A IL212371A0 (en) | 2003-05-27 | 2011-04-14 | Novel compounds |
HR20110359T HRP20110359T1 (hr) | 2003-05-27 | 2011-05-16 | Upotreba derivata 3-feniltio-1h-indol-1-octene kiseline kao modulatora crth2 receptorske aktivnosti |
CY20111100464T CY1111469T1 (el) | 2003-05-27 | 2011-05-16 | ΧΡΗΣΗ ΠΑΡΑΓΩΓΩΝ 3-ΦΑΙΝΥΛΘΕΙΟ-1Η-ΙΝΔΟΛΗ-1-ΟΞΙΚΟΥ ΟΞΕΟΣ ΩΣ ΡΥΘΜΙΣΤΕΣ ΤΗΣ ΔΡΑΣΗΣ ΤΟΥ ΥΠΟΔΟΧΕΑ CRTh2 |
US13/344,051 US20120178764A1 (en) | 2003-05-27 | 2012-01-05 | Novel Compounds |
HRP20120390TT HRP20120390T1 (hr) | 2003-05-27 | 2012-05-10 | Intermedijarni spoj etil estera 4-(acetilamino)-3-[(4-klorofenil)tio]-2-metil-1h-indol-1-octene kiseline |
CY20121100486T CY1112853T1 (el) | 2003-05-27 | 2012-05-29 | Ενδιαμεση ενωση 4-(ακετυλαμινο)-3-[(4-χλωροφαινυλ)θειο]-2-μεθυλ-1η-ινδολη-1-οξικο οξυ αιθυλεστερα |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0301569A SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Novel compounds |
SE0302305A SE0302305D0 (sv) | 2003-05-27 | 2003-08-27 | Novel Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0301569D0 true SE0301569D0 (sv) | 2003-05-27 |
Family
ID=33492578
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0301569A SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Novel compounds |
SE0302305A SE0302305D0 (sv) | 2003-05-27 | 2003-08-27 | Novel Compounds |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0302305A SE0302305D0 (sv) | 2003-05-27 | 2003-08-27 | Novel Compounds |
Country Status (31)
Country | Link |
---|---|
US (4) | US7687535B2 (xx) |
EP (3) | EP1656346B1 (xx) |
JP (2) | JP4541361B2 (xx) |
KR (3) | KR101067535B1 (xx) |
CN (2) | CN102391171A (xx) |
AR (1) | AR044552A1 (xx) |
AT (3) | ATE425965T1 (xx) |
AU (1) | AU2004242624B2 (xx) |
BR (1) | BRPI0410711B8 (xx) |
CA (1) | CA2526866C (xx) |
CO (1) | CO5630030A2 (xx) |
CY (3) | CY1109104T1 (xx) |
DE (2) | DE602004020072D1 (xx) |
DK (3) | DK1656346T3 (xx) |
ES (3) | ES2361485T3 (xx) |
HK (3) | HK1090635A1 (xx) |
HR (3) | HRP20090281T1 (xx) |
IL (4) | IL171928A (xx) |
IS (2) | IS2722B (xx) |
MX (1) | MXPA05012680A (xx) |
MY (1) | MY144483A (xx) |
NO (1) | NO20056130L (xx) |
NZ (1) | NZ543722A (xx) |
PL (3) | PL1656346T3 (xx) |
PT (3) | PT2025670E (xx) |
RU (1) | RU2361860C2 (xx) |
SE (2) | SE0301569D0 (xx) |
SI (3) | SI2281815T1 (xx) |
TW (2) | TW201024261A (xx) |
WO (1) | WO2004106302A1 (xx) |
ZA (1) | ZA200509598B (xx) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200307542A (en) * | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) * | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0301569D0 (sv) * | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
SE0303180D0 (sv) * | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
DK1725553T3 (da) | 2004-03-11 | 2008-08-18 | Actelion Pharmaceuticals Ltd | Tetrahydropyridoindolderivater |
ES2369782T3 (es) | 2004-12-27 | 2011-12-05 | Actelion Pharmaceuticals Ltd. | Derivados de 2,3,4,9-tetrahidro-1h-carbazol como antagonistas del receptor crth2. |
GB0500604D0 (en) * | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
DOP2006000016A (es) * | 2005-01-26 | 2006-07-31 | Aventis Pharma Inc | 2-fenil-indoles como antagonistas del receptor de la prostaglandina d2. |
US8796280B2 (en) | 2005-04-21 | 2014-08-05 | Merck Serono, S.A. | 2,3-disubstituted pyrazinesulfonamides as CRTH2 inhibitors |
WO2006125784A1 (en) | 2005-05-24 | 2006-11-30 | Laboratoires Serono S.A. | Tricyclic spiro derivatives as crth2 modulators |
JP5072594B2 (ja) | 2005-07-22 | 2012-11-14 | 塩野義製薬株式会社 | Pgd2受容体アンタゴニスト活性を有するインドール誘導体 |
WO2007010965A1 (ja) | 2005-07-22 | 2007-01-25 | Shionogi & Co., Ltd. | Pgd2受容体アンタゴニスト活性を有するアザインドール酸誘導体 |
RU2405770C2 (ru) | 2005-09-27 | 2010-12-10 | Сионоги Энд Ко., Лтд. | Производное сульфонамида, обладающее антагонистической активностью в отношении рецептора pgd2 |
BRPI0616452B8 (pt) * | 2005-09-30 | 2021-05-25 | Argenta Discovery Ltd | quinolinas e seu uso terapêutico |
CN101454284A (zh) * | 2006-05-26 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
DK2037967T3 (en) | 2006-06-16 | 2017-03-13 | Univ Pennsylvania | PROSTAGLANDIN-D2 RECEPTOR ANTAGONISTS FOR TREATMENT OF ANDROGENETIC ALOPECI |
EP2046740B1 (en) * | 2006-07-22 | 2012-05-23 | Oxagen Limited | Compounds having crth2 antagonist activity |
KR101411820B1 (ko) | 2006-08-07 | 2014-06-24 | 액테리온 파마슈티칼 리미티드 | (3-아미노-1,2,3,4-테트라하이드로-9h-카르바졸-9-일)-아세트산 유도체 |
GB0702456D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination |
JP2010530425A (ja) * | 2007-06-21 | 2010-09-09 | アクチミス ファーマシューティカルズ インコーポレーテッド | Crth2アンタゴニストの粒子 |
US8278310B2 (en) * | 2007-06-21 | 2012-10-02 | Actimis Pharmaceuticals, Inc. | Amine salts of a CRTH2 antagonist |
EP2229358B1 (en) | 2007-12-14 | 2011-03-23 | Pulmagen Therapeutics (Asthma) Limited | Indoles and their therapeutic use |
US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
US20110312945A1 (en) * | 2008-10-01 | 2011-12-22 | James Jia | Crth2 modulators |
US8273769B2 (en) | 2009-02-12 | 2012-09-25 | Merck Serono Sa | Phenoxy acetic acid derivatives |
TW201118067A (en) * | 2009-07-06 | 2011-06-01 | Astrazeneca Ab | Pharmaceutical process and intermediates |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
US9032565B2 (en) | 2009-12-16 | 2015-05-19 | Kohler Co. | Touchless faucet assembly and method of operation |
WO2011073662A1 (en) | 2009-12-17 | 2011-06-23 | Astrazeneca Ab | Combination of a benzoxazinone and a further agent for treating respiratory diseases |
BR112012024114B1 (pt) | 2010-03-22 | 2021-02-09 | Idorsia Pharmaceuticals Ltd | Compostos derivados de 3-(heteroarilamino)-1,2,3,4-tetrahidro-9h-carbazol, uso dos mesmos, e, composição farmacêutica |
GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
AU2012241442B2 (en) | 2011-04-14 | 2017-01-12 | Idorsia Pharmaceuticals Ltd | 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido(1,2-a)indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators |
MX2014007239A (es) | 2011-12-16 | 2014-08-08 | Atopix Therapeutics Ltd | Combinacion de un antagonista crth2 y un inhibidor de bomba de proton para el tratamiento de esofagitis eosinofilica. |
CN104602763B (zh) | 2012-03-21 | 2018-08-21 | 宾夕法尼亚大学理事会 | 用于调节毛发生长的组合物和方法 |
US9550750B2 (en) * | 2012-10-05 | 2017-01-24 | Merck Sharp & Dohme Corp. | Indoline compounds as aldosterone synthase inhibitors |
RU2680100C9 (ru) * | 2013-03-15 | 2019-04-18 | Плексксикон Инк. | Гетероциклические соединения и их применения |
US20140303121A1 (en) | 2013-03-15 | 2014-10-09 | Plexxikon Inc. | Heterocyclic compounds and uses thereof |
CN105473578A (zh) * | 2013-05-24 | 2016-04-06 | 加州生物医学研究所 | 用于治疗抗药性和持续性结核病的化合物 |
LT3119779T (lt) | 2014-03-17 | 2018-09-10 | Idorsia Pharmaceuticals Ltd | Azaindolo acto rūgšties dariniai ir jų panaudojimas kaip prostaglandino d2 receptoriaus moduliatorių |
TW201620909A (zh) | 2014-03-18 | 2016-06-16 | 艾克泰聯製藥有限公司 | 氮雜吲哚乙酸衍生物及彼等作為前列腺素d2受體調節劑之用途 |
GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
CN108472510A (zh) | 2015-07-30 | 2018-08-31 | 宾夕法尼亚大学理事会 | 用于检测pgd2对毛发生长抑制的易感性的人dp-2基因的单核苷酸多态性等位基因 |
MX2018003202A (es) | 2015-09-15 | 2018-06-08 | Idorsia Pharmaceuticals Ltd | Formas cristalinas. |
EP3694855A1 (en) | 2017-10-13 | 2020-08-19 | Plexxikon Inc. | Solid forms of a compound for modulating kinases |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE790679A (fr) | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
JPH0615542B2 (ja) | 1986-07-22 | 1994-03-02 | 吉富製薬株式会社 | ピラゾロピリジン化合物 |
US5095031A (en) * | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
WO1993005020A1 (en) | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
FR2692574B1 (fr) | 1992-06-23 | 1995-06-23 | Sanofi Elf | Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles. |
BR9405737A (pt) | 1993-02-24 | 1995-12-05 | Merck & Co Inc | Composto processo de inibição de transcriptase reserva de HIV, processo de prevenção contra a infecção pelo HIV ou de tratamento da infecção pelo HIV, composição farmacêutica útil para a inibição da transcriptase reserva de HIV, e, útil para a prevenção ou tratamento de infecção pelo HIV ou para o tratamento da AIDS ou ARC |
US5486525A (en) | 1993-12-16 | 1996-01-23 | Abbott Laboratories | Platelet activating factor antagonists: imidazopyridine indoles |
US5567711A (en) * | 1995-04-19 | 1996-10-22 | Abbott Laboratories | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists |
GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
SK285141B6 (sk) | 1996-02-13 | 2006-07-07 | Astrazeneca Uk Limited | Použitie chinazolínového derivátu, chinazolínový derivát, spôsob jeho prípravy a farmaceutická kompozícia, ktorá ho obsahuje |
EP0885198B1 (en) | 1996-03-05 | 2001-12-19 | AstraZeneca AB | 4-anilinoquinazoline derivatives |
TW472045B (en) | 1996-09-25 | 2002-01-11 | Astra Ab | Protein kinase C inhibitor compounds, method for their preparation, pharmaceutical composition thereof and intermediate used for their preparation |
GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
WO1999009007A1 (en) | 1997-08-21 | 1999-02-25 | American Home Products Corporation | Solid phase synthesis of 2,3-disubstituted indole compounds |
DK0924209T3 (da) | 1997-12-19 | 2003-08-25 | Lilly Co Eli | Hypoglykæmiske imidazolinforbindelser |
US6916841B2 (en) * | 1998-02-25 | 2005-07-12 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
WO2000078761A1 (en) | 1999-06-23 | 2000-12-28 | Sepracor, Inc. | Indolyl-benzimidazole antibacterials, and methods of use thereof |
AU7962200A (en) | 1999-10-29 | 2001-05-14 | Wakunaga Pharmaceutical Co., Ltd | Novel indole derivatives and drugs containing the same as the active ingredient |
CN100379734C (zh) | 1999-12-24 | 2008-04-09 | 阿文蒂斯药物有限公司 | 氮杂吲哚类化合物 |
MXPA02011770A (es) | 2000-05-31 | 2003-04-10 | Astrazeneca Ab | Derivados de indol con actividad de dano vascular. |
US6878522B2 (en) * | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
IL153484A0 (en) | 2000-07-07 | 2003-07-06 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors |
WO2002008213A1 (en) | 2000-07-07 | 2002-01-31 | Angiogene Pharmaceuticals Limited | Colchinol derivatives as angiogenesis inhibitors |
JP4595182B2 (ja) * | 2000-09-07 | 2010-12-08 | ソニー株式会社 | 情報記録装置、情報再生装置、情報記録方法、情報再生方法、および情報記録媒体、並びにプログラム提供媒体 |
US6933316B2 (en) * | 2001-12-13 | 2005-08-23 | National Health Research Institutes | Indole compounds |
EP1501826B1 (en) | 2002-02-01 | 2006-09-27 | F. Hoffman-la Roche AG | Substituted indoles as alpha-1 agonists |
SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
WO2003097598A1 (fr) | 2002-05-16 | 2003-11-27 | Shionogi & Co., Ltd. | Composé comprenant un antagonisme du récepteur de pdg2 |
SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
TW200307542A (en) * | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) * | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0202463D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
US20070232681A1 (en) | 2003-10-14 | 2007-10-04 | Oxagen Limited | Compounds Having Crth2 Antagonist Activity |
SE0303180D0 (sv) * | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
GB0500604D0 (en) * | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
GB2422831A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
CN101454284A (zh) | 2006-05-26 | 2009-06-10 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
BRPI0712139A2 (pt) | 2006-06-08 | 2012-01-10 | Neurokey As | uso de agonistas receptores de canabinóide como fármacos indutores de hipotermia para o tratamento da isquemia |
EP2040688B1 (en) | 2006-06-28 | 2014-04-02 | Sanofi | New cxcr2 inhibitors |
-
2003
- 2003-05-27 SE SE0301569A patent/SE0301569D0/xx unknown
- 2003-08-27 SE SE0302305A patent/SE0302305D0/xx unknown
-
2004
- 2004-05-19 TW TW099109193A patent/TW201024261A/zh unknown
- 2004-05-19 TW TW093114113A patent/TWI328004B/zh not_active IP Right Cessation
- 2004-05-24 AR ARP040101792A patent/AR044552A1/es unknown
- 2004-05-25 MX MXPA05012680A patent/MXPA05012680A/es active IP Right Grant
- 2004-05-25 PL PL04734774T patent/PL1656346T3/pl unknown
- 2004-05-25 CN CN2011102633202A patent/CN102391171A/zh active Pending
- 2004-05-25 EP EP04734774A patent/EP1656346B1/en not_active Expired - Lifetime
- 2004-05-25 DE DE602004020072T patent/DE602004020072D1/de not_active Expired - Lifetime
- 2004-05-25 DK DK04734774T patent/DK1656346T3/da active
- 2004-05-25 SI SI200431874T patent/SI2281815T1/sl unknown
- 2004-05-25 JP JP2006532212A patent/JP4541361B2/ja not_active Expired - Fee Related
- 2004-05-25 ES ES08165755T patent/ES2361485T3/es not_active Expired - Lifetime
- 2004-05-25 DK DK10180348.4T patent/DK2281815T3/da active
- 2004-05-25 AT AT04734774T patent/ATE425965T1/de active
- 2004-05-25 DE DE602004031894T patent/DE602004031894D1/de not_active Expired - Lifetime
- 2004-05-25 AT AT10180348T patent/ATE552243T1/de active
- 2004-05-25 PT PT08165755T patent/PT2025670E/pt unknown
- 2004-05-25 BR BRPI0410711A patent/BRPI0410711B8/pt not_active IP Right Cessation
- 2004-05-25 EP EP10180348A patent/EP2281815B1/en not_active Expired - Lifetime
- 2004-05-25 ES ES04734774T patent/ES2322650T3/es not_active Expired - Lifetime
- 2004-05-25 KR KR1020117009788A patent/KR101067535B1/ko not_active IP Right Cessation
- 2004-05-25 RU RU2005137403/04A patent/RU2361860C2/ru active
- 2004-05-25 WO PCT/SE2004/000808 patent/WO2004106302A1/en active Application Filing
- 2004-05-25 PT PT10180348T patent/PT2281815E/pt unknown
- 2004-05-25 SI SI200431669T patent/SI2025670T1/sl unknown
- 2004-05-25 CN CN2004800146027A patent/CN1795174B/zh not_active Expired - Fee Related
- 2004-05-25 NZ NZ543722A patent/NZ543722A/xx not_active IP Right Cessation
- 2004-05-25 KR KR1020117009790A patent/KR20110050754A/ko not_active Application Discontinuation
- 2004-05-25 PT PT04734774T patent/PT1656346E/pt unknown
- 2004-05-25 AT AT08165755T patent/ATE502010T1/de active
- 2004-05-25 AU AU2004242624A patent/AU2004242624B2/en not_active Ceased
- 2004-05-25 DK DK08165755.3T patent/DK2025670T3/da active
- 2004-05-25 ES ES10180348T patent/ES2382606T3/es not_active Expired - Lifetime
- 2004-05-25 PL PL10180348T patent/PL2281815T3/pl unknown
- 2004-05-25 MY MYPI20041992A patent/MY144483A/en unknown
- 2004-05-25 CA CA2526866A patent/CA2526866C/en not_active Expired - Fee Related
- 2004-05-25 US US10/558,228 patent/US7687535B2/en active Active
- 2004-05-25 EP EP08165755A patent/EP2025670B1/en not_active Expired - Lifetime
- 2004-05-25 KR KR1020057022513A patent/KR101067586B1/ko active IP Right Grant
- 2004-05-25 PL PL08165755T patent/PL2025670T3/pl unknown
- 2004-05-25 SI SI200431120T patent/SI1656346T1/sl unknown
-
2005
- 2005-11-14 IL IL171928A patent/IL171928A/en not_active IP Right Cessation
- 2005-11-23 CO CO05118882A patent/CO5630030A2/es active IP Right Grant
- 2005-11-28 ZA ZA200509598A patent/ZA200509598B/en unknown
- 2005-12-20 IS IS8189A patent/IS2722B/is unknown
- 2005-12-22 NO NO20056130A patent/NO20056130L/no not_active Application Discontinuation
-
2006
- 2006-10-11 HK HK06111158.9A patent/HK1090635A1/xx not_active IP Right Cessation
-
2008
- 2008-10-23 IL IL194872A patent/IL194872A0/en unknown
-
2009
- 2009-03-04 US US12/397,618 patent/US20090163518A1/en not_active Abandoned
- 2009-05-15 HR HR20090281T patent/HRP20090281T1/xx unknown
- 2009-05-28 CY CY20091100564T patent/CY1109104T1/el unknown
- 2009-06-30 HK HK09105852.7A patent/HK1126773A1/xx not_active IP Right Cessation
- 2009-06-30 HK HK11107570.0A patent/HK1149563A1/xx not_active IP Right Cessation
-
2010
- 2010-03-31 JP JP2010082748A patent/JP2010155862A/ja active Pending
- 2010-08-09 IS IS8920A patent/IS8920A/is unknown
-
2011
- 2011-03-14 US US13/047,280 patent/US20110263614A1/en not_active Abandoned
- 2011-04-11 IL IL212265A patent/IL212265A0/en unknown
- 2011-04-14 IL IL212371A patent/IL212371A0/en unknown
- 2011-05-16 CY CY20111100464T patent/CY1111469T1/el unknown
- 2011-05-16 HR HR20110359T patent/HRP20110359T1/hr unknown
-
2012
- 2012-01-05 US US13/344,051 patent/US20120178764A1/en not_active Abandoned
- 2012-05-10 HR HRP20120390TT patent/HRP20120390T1/hr unknown
- 2012-05-29 CY CY20121100486T patent/CY1112853T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE0302305D0 (sv) | Novel Compounds | |
DK1605897T3 (da) | Polyethelen-glycol-link-glp-1-forbindelser | |
IS8108A (is) | Ný efnasambönd | |
IS8228A (is) | Ný asetídínefnasambönd | |
ECSP066436A (es) | Compuestos heterociclicos fusionados | |
ATE368042T1 (de) | Cephemverbindungen | |
IS8089A (is) | Efnasambönd | |
IS7381A (is) | Efnasambönd | |
IS8292A (is) | Ný efnasambönd | |
IS7414A (is) | Oxó-azabísýklísk efnasambönd | |
AT502792A5 (de) | Düsenanpressvorrichtung | |
NO20045659L (no) | Forbindelser | |
DK1633719T3 (da) | Substituerede spirobenzazepiner | |
DE502004009935D1 (de) | Substituierte dihydrochinazoline ii | |
NO20031736D0 (no) | Forbindelser | |
SE0303452D0 (sv) | New compounds | |
SE0203348D0 (sv) | Novel compounds | |
SE0300118D0 (sv) | Novel Compounds | |
SE0302667D0 (sv) | Novel Compounds | |
SE0300388D0 (sv) | Novel compounds | |
AT6592U3 (de) | Frontgrubber | |
NO20030117D0 (no) | Forbindelser | |
NO20033173D0 (no) | Forbindelser | |
NO20035294D0 (no) | Forbindelser | |
SE0301246D0 (sv) | New compounds |