RU2766690C2 - Модифицированные моноциты/макрофаги, экспрессирующие химерные антигенные рецепторы, и их применения - Google Patents

Модифицированные моноциты/макрофаги, экспрессирующие химерные антигенные рецепторы, и их применения Download PDF

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RU2766690C2
RU2766690C2 RU2018107047A RU2018107047A RU2766690C2 RU 2766690 C2 RU2766690 C2 RU 2766690C2 RU 2018107047 A RU2018107047 A RU 2018107047A RU 2018107047 A RU2018107047 A RU 2018107047A RU 2766690 C2 RU2766690 C2 RU 2766690C2
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car
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antibody
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tumor
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Саар ДЖИЛЛ
Майкл КЛИЧИНСКИ
Карл Х. Джун
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
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RU2018107047A 2015-07-28 2016-07-28 Модифицированные моноциты/макрофаги, экспрессирующие химерные антигенные рецепторы, и их применения RU2766690C2 (ru)

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US201562197675P 2015-07-28 2015-07-28
US62/197,675 2015-07-28
PCT/US2016/044440 WO2017019848A1 (en) 2015-07-28 2016-07-28 Modified monocytes/macrophage expressing chimeric antigen receptors and uses thereof

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RU2018107047A3 RU2018107047A3 (enExample) 2020-02-27
RU2766690C2 true RU2766690C2 (ru) 2022-03-15

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Cited By (1)

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RU2846905C1 (ru) * 2024-12-28 2025-09-18 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр эндокринологии имени академика И.И.Дедова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ эндокринологии им. академика И.И. Дедова" Минздрава России) Способ анализа макрофагов и их субпопуляций в иммунном микроокружении нейроэндокринных опухолей гипофиза при помощи многопараметрической проточной цитометрии

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US10434153B1 (en) 2015-05-20 2019-10-08 Kim Leslie O'Neill Use of car and bite technology coupled with an scFv from an antibody against human thymidine kinase 1 to specifically target tumors
KR102697827B1 (ko) * 2015-07-28 2024-08-23 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 키메릭 항원 수용체를 발현하는 변형된 단핵세포/대식세포 및 그의 용도
WO2017025944A2 (en) * 2015-08-13 2017-02-16 Brigham Young University Macrophage car (moto-car) in imunotherapy
US11352439B2 (en) * 2015-08-13 2022-06-07 Kim Leslie O'Neill Macrophage CAR (MOTO-CAR) in immunotherapy
AU2016318773B2 (en) 2015-09-09 2024-08-01 Seattle Children's Hospital (dba Seattle Children's Research Institute) Genetic engineering of macrophages for immunotherapy
US10875919B2 (en) * 2016-04-26 2020-12-29 Alector Llc Chimeric receptors and methods of use thereof
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RU2846905C1 (ru) * 2024-12-28 2025-09-18 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр эндокринологии имени академика И.И.Дедова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ эндокринологии им. академика И.И. Дедова" Минздрава России) Способ анализа макрофагов и их субпопуляций в иммунном микроокружении нейроэндокринных опухолей гипофиза при помощи многопараметрической проточной цитометрии

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