RU2750164C2 - Цианотиенотриазолодиазепины и пути их применения - Google Patents
Цианотиенотриазолодиазепины и пути их применения Download PDFInfo
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- RU2750164C2 RU2750164C2 RU2018112961A RU2018112961A RU2750164C2 RU 2750164 C2 RU2750164 C2 RU 2750164C2 RU 2018112961 A RU2018112961 A RU 2018112961A RU 2018112961 A RU2018112961 A RU 2018112961A RU 2750164 C2 RU2750164 C2 RU 2750164C2
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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| KR20160115953A (ko) | 2014-01-31 | 2016-10-06 | 다나-파버 캔서 인스티튜트 인크. | 디아미노피리미딘 벤젠술폰 유도체 및 그의 용도 |
| CA2996974A1 (en) | 2015-09-11 | 2017-03-16 | Dana-Farber Cancer Institute, Inc. | Cyano thienotriazolodiazepines and uses thereof |
| JP2018526424A (ja) | 2015-09-11 | 2018-09-13 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | アセトアミドチエノトリアゾロジアゼピンおよびこれらの使用 |
| RU2742035C2 (ru) | 2015-11-25 | 2021-02-01 | Дана-Фарбер Кэнсер Инститьют, Инк. | Бивалентные ингибиторы бромодоменов и пути их применения |
| CA3076759A1 (en) * | 2017-09-22 | 2019-03-28 | Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. | Thienodiazepine derivatives and application thereof |
| CN108084193A (zh) * | 2017-12-19 | 2018-05-29 | 郭守东 | 一种brd4蛋白抑制剂 |
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| WO2020160198A1 (en) | 2019-01-29 | 2020-08-06 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| EP3917529A4 (en) | 2019-01-29 | 2022-11-02 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| WO2021175432A1 (en) | 2020-03-04 | 2021-09-10 | Boehringer Ingelheim International Gmbh | Method for administration of an anti cancer agent |
| WO2022221786A2 (en) * | 2022-06-22 | 2022-10-20 | Plexium, Inc. | Compounds and pharmaceutical compositions that modulate brd4 |
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- 2016-09-09 US US15/758,822 patent/US11306105B2/en active Active
- 2016-09-09 RU RU2018112961A patent/RU2750164C2/ru active
- 2016-09-09 KR KR1020187009782A patent/KR20180049058A/ko not_active Withdrawn
- 2016-09-09 CN CN201680062106.1A patent/CN108472300A/zh active Pending
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- 2016-09-09 HK HK18115549.4A patent/HK1256417A1/zh unknown
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| CA2996974A1 (en) | 2017-03-16 |
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| BR112018004618A2 (pt) | 2018-09-25 |
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| US20210206779A9 (en) | 2021-07-08 |
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| CL2020002530A1 (es) | 2021-01-29 |
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| AU2016319116B2 (en) | 2020-10-01 |
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| US11306105B2 (en) | 2022-04-19 |
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| AU2016319116A1 (en) | 2018-03-29 |
| RU2018112961A (ru) | 2019-10-11 |
| EP3347021A4 (en) | 2019-07-24 |
| WO2017044849A8 (en) | 2017-09-28 |
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