RU2661408C2 - Вакцинная композиция для применения в популяциях субъектов с ослабленным иммунитетом - Google Patents

Вакцинная композиция для применения в популяциях субъектов с ослабленным иммунитетом Download PDF

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RU2661408C2
RU2661408C2 RU2015129077A RU2015129077A RU2661408C2 RU 2661408 C2 RU2661408 C2 RU 2661408C2 RU 2015129077 A RU2015129077 A RU 2015129077A RU 2015129077 A RU2015129077 A RU 2015129077A RU 2661408 C2 RU2661408 C2 RU 2661408C2
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acid
virus
vaccine
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influenza
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RU2015129077A
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RU2015129077A (ru
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Ханс АРВИДССОН
Анна-Карин МАЛЬТАИС
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Юросайн Вэксинз Аб
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
RU2015129077A 2012-12-17 2013-12-17 Вакцинная композиция для применения в популяциях субъектов с ослабленным иммунитетом RU2661408C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12197522.1A EP2742952A1 (en) 2012-12-17 2012-12-17 Influenza vaccine composition
EP12197522.1 2012-12-17
PCT/EP2013/077007 WO2014095944A1 (en) 2012-12-17 2013-12-17 Vaccine composition for use in immuno-compromised populations

Publications (2)

Publication Number Publication Date
RU2015129077A RU2015129077A (ru) 2017-01-23
RU2661408C2 true RU2661408C2 (ru) 2018-07-16

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RU2015129077A RU2661408C2 (ru) 2012-12-17 2013-12-17 Вакцинная композиция для применения в популяциях субъектов с ослабленным иммунитетом
RU2015129028A RU2661407C2 (ru) 2012-12-17 2013-12-17 Вакцинная композиция для неиммунизированных индивидуумов

Family Applications After (1)

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RU2015129028A RU2661407C2 (ru) 2012-12-17 2013-12-17 Вакцинная композиция для неиммунизированных индивидуумов

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US (2) US20150306204A1 (OSRAM)
EP (4) EP2742952A1 (OSRAM)
JP (3) JP2016502997A (OSRAM)
KR (3) KR20210007042A (OSRAM)
CN (3) CN112826929A (OSRAM)
AU (2) AU2013360889C1 (OSRAM)
BR (2) BR112015014174A2 (OSRAM)
CA (2) CA2895028A1 (OSRAM)
HK (2) HK1212611A1 (OSRAM)
MX (2) MX2015007753A (OSRAM)
RU (2) RU2661408C2 (OSRAM)
WO (2) WO2014095943A1 (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103298484B (zh) * 2010-09-30 2017-04-26 优若森疫苗公司 改进的疫苗组合物
EP4144369A1 (en) * 2014-09-26 2023-03-08 Seqirus UK Limited Vaccination of immunocompromised subjects
JP2017528511A (ja) 2014-09-26 2017-09-28 セキラス ユーケー リミテッド 免疫低下された被験体のワクチン接種
RU2634247C2 (ru) * 2015-09-28 2017-10-24 Федеральное государственное бюджетное научное учреждение "СЕВЕРО-КАВКАЗСКИЙ ЗОНАЛЬНЫЙ НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ВЕТЕРИНАРНЫЙ ИНСТИТУТ" (ФГБНУ СКЗНИВИ) Способ стимуляции иммунного ответа и препарат для его осуществления
US20200306364A1 (en) * 2017-11-30 2020-10-01 Ohio State Innovation Foundation Mucoadhesive nanoparticle entrapped influenza virus vaccine delivery system
EP4135519B1 (en) * 2020-04-16 2024-09-25 Bayer Aktiengesellschaft Active compound combinations and fungicide compositions comprising those
US20230133087A1 (en) * 2020-04-16 2023-05-04 Bayer Aktiengesellschaft Active compound combinations and fungicide compositions comprising those
WO2021209364A1 (en) * 2020-04-16 2021-10-21 Bayer Aktiengesellschaft Active compound combinations and fungicide compositions comprising those
CN112063699B (zh) * 2020-09-16 2021-06-18 成都市疾病预防控制中心 一种用于研究hiv感染者免疫衰老机制的系统
WO2023133342A2 (en) * 2022-01-10 2023-07-13 The Children's Medical Center Corporation Methods and compositions relating to immunization of immune distinct patients

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2323742C1 (ru) * 2007-02-15 2008-05-10 Государственное учреждение Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова (ГУ НИИВС им. И.И. Мечникова) Способ повышения иммуногенности инактивированной гриппозной вакцины
WO2012042003A1 (en) * 2010-09-30 2012-04-05 Eurocine Vaccines Ab Improved vaccine compositions

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9602280D0 (sv) 1996-06-10 1996-06-10 Pharmatrix Ab Immunstimulerande lipidformulering
SE9900496D0 (sv) 1999-02-12 1999-02-12 Pharmatrix Ab Vaccine formulation
US8410248B2 (en) 1999-03-12 2013-04-02 Human Genome Sciences Inc. HWBAO62 polypeptides
JP2004527524A (ja) 2001-04-05 2004-09-09 カイロン コーポレイション 非経口初回抗原刺激後の粘膜追加免疫
US20050208602A1 (en) 2001-08-10 2005-09-22 Rosen Craig A 89 human secreted proteins
WO2004042000A2 (en) 2002-05-17 2004-05-21 Human Genome Sciences, Inc. 157 human secreted proteins
DK1567191T3 (da) 2002-11-26 2011-01-03 Eurocine Vaccines Ab Ny amin-baseret adjuvans
CN1867355A (zh) 2003-08-11 2006-11-22 财团法人阪大微生物病研究会 包含诱导粘膜免疫的佐剂的新型疫苗
WO2006125076A2 (en) 2005-05-18 2006-11-23 Trinity Biosystems, Inc. Methods and compositions for immunizing against chlamydia infection
KR101294455B1 (ko) 2005-06-30 2013-08-07 에자이 알앤드디 매니지먼트 가부시키가이샤 면역 아쥬반트 제조용 화합물
US8211442B2 (en) 2005-08-05 2012-07-03 The University Of Tokushima Mucosal vaccine enabling switching from production of IgA antibody to production of both of IgA and IgG antibodies
EP2227251A1 (en) * 2007-12-06 2010-09-15 GlaxoSmithKline Biologicals SA Influenza composition
CA2725381A1 (en) 2008-05-23 2010-03-25 The Regents Of The University Of Michigan Nanoemulsion adjuvants
US9415006B2 (en) 2008-05-23 2016-08-16 The Regents Of The University Of Michigan Immunogenic compositions comprising nanoemulsion and hepatitis B virus immunogen and methods of using the same
US20130178383A1 (en) 2008-11-12 2013-07-11 David Spetzler Vesicle isolation methods
ES2618576T3 (es) 2009-05-28 2017-06-21 Curna, Inc. Tratamiento de enfermedades relacionadas con un gen antivírico mediante la inhibición de una transcripción antisentido natural a un gen antivírico

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2323742C1 (ru) * 2007-02-15 2008-05-10 Государственное учреждение Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова (ГУ НИИВС им. И.И. Мечникова) Способ повышения иммуногенности инактивированной гриппозной вакцины
WO2012042003A1 (en) * 2010-09-30 2012-04-05 Eurocine Vaccines Ab Improved vaccine compositions

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HANA HAKIM et al. Immunogenicity and safety of inactivated monovalent 2009 H1N1 influenza A vaccine in immunocompromised children and young adults//VaccineVolume 30, Issue 5, 20 January 2012, Pages 879-885 он лайн найдено 12.12.2017 найдено из Интернет: http://www.sciencedirect.com/science/article/pii/S0264410X11019013. *
HANA HAKIM et al. Immunogenicity and safety of inactivated monovalent 2009 H1N1 influenza A vaccine in immunocompromised children and young adults//VaccineVolume 30, Issue 5, 20 January 2012, Pages 879-885 реферат он лайн найдено 12.12.2017 найдено из Интернет: http://www.sciencedirect.com/science/article/pii/S0264410X11019013. PETERSSON P. et al. The Eurocine& α χ ι ρ χ ; L3 adjuvants with subunit influenza antigens induce protective immunity in mice after intranasal vaccination//VaccineVolume 28, Issue 39, 7 September 2010, Pages 6491-6497 реферат он лайн найдено 12.12.2017, найдено из Интернет:http://www.sciencedirect.com/science/article/pii/S0264410X10009540. *
PETERSSON P. et al. The Eurocine& α χ ι ρ χ ; L3 adjuvants with subunit influenza antigens induce protective immunity in mice after intranasal vaccination//VaccineVolume 28, Issue 39, 7 September 2010, Pages 6491-6497 он лайн найдено 12.12.2017, найдено из Интернет:http://www.sciencedirect.com/science/article/pii/S0264410X10009540. *

Also Published As

Publication number Publication date
EP3431101A1 (en) 2019-01-23
RU2015129028A (ru) 2017-01-23
CN112826929A (zh) 2021-05-25
AU2013360889B2 (en) 2016-12-01
AU2013360890A1 (en) 2015-07-02
JP2016502996A (ja) 2016-02-01
EP2742952A1 (en) 2014-06-18
CA2895023A1 (en) 2014-06-26
AU2013360890B2 (en) 2017-04-13
BR112015014243A2 (pt) 2017-07-11
AU2013360889C1 (en) 2017-06-08
KR20210007042A (ko) 2021-01-19
BR112015014174A2 (pt) 2017-07-11
KR20150132093A (ko) 2015-11-25
CN104884085A (zh) 2015-09-02
MX2015007688A (es) 2015-09-07
WO2014095943A1 (en) 2014-06-26
MX2015007753A (es) 2016-01-08
JP2019112448A (ja) 2019-07-11
BR112015014243A8 (pt) 2019-10-08
JP2016502997A (ja) 2016-02-01
EP2931308A1 (en) 2015-10-21
RU2661407C2 (ru) 2018-07-16
EP2931307B1 (en) 2018-09-12
HK1213492A1 (zh) 2016-07-08
EP2931308B1 (en) 2018-10-10
RU2015129077A (ru) 2017-01-23
CN104870010A (zh) 2015-08-26
KR20150132092A (ko) 2015-11-25
AU2013360889A1 (en) 2015-07-02
HK1212611A1 (zh) 2016-06-17
EP2931307A1 (en) 2015-10-21
US20150306205A1 (en) 2015-10-29
WO2014095944A1 (en) 2014-06-26
US20150306204A1 (en) 2015-10-29
US11065325B2 (en) 2021-07-20
CA2895028A1 (en) 2014-06-26

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Effective date: 20191218