RU2625767C2 - Твердая фармацевтическая композиция, содержащая 1-(3-(2-(1-бензотиофен-5-ил)этокси)пропил)азетидин-3-ол или его соль - Google Patents
Твердая фармацевтическая композиция, содержащая 1-(3-(2-(1-бензотиофен-5-ил)этокси)пропил)азетидин-3-ол или его соль Download PDFInfo
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- RU2625767C2 RU2625767C2 RU2014138035A RU2014138035A RU2625767C2 RU 2625767 C2 RU2625767 C2 RU 2625767C2 RU 2014138035 A RU2014138035 A RU 2014138035A RU 2014138035 A RU2014138035 A RU 2014138035A RU 2625767 C2 RU2625767 C2 RU 2625767C2
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- tablet
- salt
- solid pharmaceutical
- mannitol
- pharmaceutical composition
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- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/288—Compounds of unknown constitution, e.g. material from plants or animals
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012035710 | 2012-02-22 | ||
| JP2012-035710 | 2012-02-22 | ||
| PCT/JP2013/054268 WO2013125617A1 (ja) | 2012-02-22 | 2013-02-21 | １－（３－（２－（１－ベンゾチオフェン－５－イル）エトキシ）プロピル）アゼチジン－３－オールまたはその塩を含有する固形医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014138035A RU2014138035A (ru) | 2016-04-10 |
| RU2625767C2 true RU2625767C2 (ru) | 2017-07-18 |
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| RU2014138035A RU2625767C2 (ru) | 2012-02-22 | 2013-02-21 | Твердая фармацевтическая композиция, содержащая 1-(3-(2-(1-бензотиофен-5-ил)этокси)пропил)азетидин-3-ол или его соль |
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| EP (1) | EP2818165B1 (enExample) |
| JP (1) | JP6054940B2 (enExample) |
| KR (1) | KR102070581B1 (enExample) |
| CN (1) | CN104159583B (enExample) |
| BR (1) | BR112014020434B1 (enExample) |
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| RU (1) | RU2625767C2 (enExample) |
| TR (1) | TR201907882T4 (enExample) |
| WO (1) | WO2013125617A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104244931A (zh) * | 2012-04-27 | 2014-12-24 | 默克专利股份有限公司 | 经包衣的片剂及其制备 |
| US10646532B2 (en) | 2014-01-29 | 2020-05-12 | National Institute Of Advanced Industrial Science And Technology | Method for preparing water extract of ashwagandha leaves which has enhanced anti-cancer activity utilizing cyclodextrin, and pharmaceutical composition containing ashwagandha leaves |
| RU2733404C2 (ru) * | 2015-12-25 | 2020-10-01 | ФУДЖИФИЛМ Тояма Кемикал Ко., Лтд. | Таблетка, включающая 1-(3-(2-(1-бензотиофен-5-ил)этокси)пропил)азетидин-3-ол или его соли |
| US20190336476A1 (en) | 2016-12-28 | 2019-11-07 | Fujifilm Toyama Chemical Co., Ltd. | Pharmaceutical composition |
| US10849880B2 (en) | 2016-12-28 | 2020-12-01 | Fujifilm Toyama Chemical Co., Ltd. | Pharmaceutical composition |
| CN110167552B (zh) * | 2016-12-28 | 2023-05-02 | 富士胶片富山化学株式会社 | 医药组合物及其制造方法 |
| EP3563843A4 (en) * | 2016-12-28 | 2019-12-11 | FUJIFILM Toyama Chemical Co., Ltd. | TOPICAL COMPOSITION |
| JP7282028B2 (ja) * | 2017-06-02 | 2023-05-26 | 富士フイルム富山化学株式会社 | 脳萎縮予防または治療剤 |
| US11541033B2 (en) | 2017-06-02 | 2023-01-03 | Fujifilm Toyama Chemical Co., Ltd. | Agent for preventing or treating Alzheimer's disease |
| NZ759657A (en) * | 2017-06-02 | 2022-07-29 | Fujifilm Toyama Chemical Co Ltd | Agent for preventing or treating tauopathy |
| JP7256118B2 (ja) | 2017-06-02 | 2023-04-11 | 富士フイルム富山化学株式会社 | アミロイドβ蛋白質量減少剤 |
| MX393700B (es) | 2017-06-02 | 2025-03-24 | Fujifilm Toyama Chemical Co Ltd | Agente para prevenir o tratar la ataxia espinocerebelosa. |
| JP7227914B2 (ja) | 2017-10-30 | 2023-02-22 | 富士フイルム富山化学株式会社 | エモパミル結合タンパク質結合剤およびその利用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2397169C2 (ru) * | 2005-03-28 | 2010-08-20 | Тояма Кемикал Ко., Лтд. | Способ получения 1-(3-(2-(1-бензотиофен-5-ил)этокси) пропил)азетидин-3-ола или его солей |
| US8026232B2 (en) * | 2008-05-28 | 2011-09-27 | Toyama Chemical Co., Ltd. | Benzothiophene oxide derivative and salt thereof |
| US20110245228A1 (en) * | 2006-08-04 | 2011-10-06 | Toyama Chemical Co., Ltd. | Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100875576B1 (ko) * | 2001-04-27 | 2008-12-23 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | 이소말토오스의 제조방법 및 용도 |
| JP4905752B2 (ja) | 2001-07-24 | 2012-03-28 | エスティー・ラボ株式会社 | 揮発性有機塩素化合物センサ |
| ES2287324T3 (es) | 2001-10-19 | 2007-12-16 | Toyama Chemical Co., Ltd. | Derivados de alquil eter o sus sales. |
| US7118765B2 (en) * | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
| JP4090309B2 (ja) | 2002-08-30 | 2008-05-28 | 帝人株式会社 | 全芳香族ポリエステルカーボネート系樹脂組成物 |
| DK1614419T3 (da) | 2003-04-17 | 2012-11-19 | Toyama Chemical Co Ltd | Midler til forebyggelse/behandling af retinale nervesygdomme, indeholdende alkyletherderivater eller salte deraf |
| US7838029B1 (en) * | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| EP1817009A2 (en) * | 2004-11-24 | 2007-08-15 | Spi Pharma, Inc. | Orally disintegrating compositions |
| KR101337382B1 (ko) | 2005-03-28 | 2013-12-06 | 토야마 케미칼 컴퍼니 리미티드 | 1-(3-(2-(1-벤조티오펜-5-일)에톡시)프로필)아제티딘-3-올 또는 그 염의 제조방법 |
| JP2007137802A (ja) | 2005-11-16 | 2007-06-07 | Takeda Chem Ind Ltd | 錠剤の製造法 |
| US20070196494A1 (en) * | 2006-02-17 | 2007-08-23 | Arnaud Grenier | Low-friability, patient-friendly orally disintegrating formulations |
| US20090208576A1 (en) * | 2006-03-31 | 2009-08-20 | Gandhi Anilkumar S | Orally Disintegrating Tablets |
| US8119625B2 (en) * | 2006-04-26 | 2012-02-21 | Toyama Chemical Co., Ltd. | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof |
| EP2583669A1 (en) * | 2007-10-10 | 2013-04-24 | Rubicon Research Private Limited | Taste-masked orally disintegrating tablets of memantine hydrochloride |
-
2013
- 2013-02-21 TR TR2019/07882T patent/TR201907882T4/tr unknown
- 2013-02-21 IN IN6995DEN2014 patent/IN2014DN06995A/en unknown
- 2013-02-21 BR BR112014020434-9A patent/BR112014020434B1/pt active IP Right Grant
- 2013-02-21 EP EP13752248.8A patent/EP2818165B1/en active Active
- 2013-02-21 US US14/379,960 patent/US9872914B2/en active Active
- 2013-02-21 KR KR1020147023511A patent/KR102070581B1/ko active Active
- 2013-02-21 JP JP2014500753A patent/JP6054940B2/ja active Active
- 2013-02-21 ES ES13752248T patent/ES2721666T3/es active Active
- 2013-02-21 DK DK13752248.8T patent/DK2818165T3/da active
- 2013-02-21 CN CN201380010472.9A patent/CN104159583B/zh active Active
- 2013-02-21 WO PCT/JP2013/054268 patent/WO2013125617A1/ja not_active Ceased
- 2013-02-21 RU RU2014138035A patent/RU2625767C2/ru active
- 2013-02-21 CA CA2865380A patent/CA2865380C/en active Active
- 2013-02-21 PL PL13752248T patent/PL2818165T3/pl unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2397169C2 (ru) * | 2005-03-28 | 2010-08-20 | Тояма Кемикал Ко., Лтд. | Способ получения 1-(3-(2-(1-бензотиофен-5-ил)этокси) пропил)азетидин-3-ола или его солей |
| US20110245228A1 (en) * | 2006-08-04 | 2011-10-06 | Toyama Chemical Co., Ltd. | Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof |
| US8026232B2 (en) * | 2008-05-28 | 2011-09-27 | Toyama Chemical Co., Ltd. | Benzothiophene oxide derivative and salt thereof |
Non-Patent Citations (1)
| Title |
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| Raymond C Rowe et al. Handbook of Pharmaceutical Excipients. SIXTH EDITION. Pharmaceutical Press and American Pharmacists Association 2009, pp.424-428, 679-682. * |
Also Published As
| Publication number | Publication date |
|---|---|
| PL2818165T3 (pl) | 2019-09-30 |
| KR20150001720A (ko) | 2015-01-06 |
| TR201907882T4 (tr) | 2019-06-21 |
| CA2865380A1 (en) | 2013-08-29 |
| KR102070581B1 (ko) | 2020-01-29 |
| WO2013125617A1 (ja) | 2013-08-29 |
| BR112014020434B1 (pt) | 2021-10-13 |
| JP6054940B2 (ja) | 2016-12-27 |
| US9872914B2 (en) | 2018-01-23 |
| US20150045345A1 (en) | 2015-02-12 |
| IN2014DN06995A (enExample) | 2015-04-10 |
| JPWO2013125617A1 (ja) | 2015-07-30 |
| EP2818165A4 (en) | 2015-07-08 |
| BR112014020434A2 (enExample) | 2017-06-20 |
| ES2721666T3 (es) | 2019-08-02 |
| CN104159583A (zh) | 2014-11-19 |
| CA2865380C (en) | 2019-10-29 |
| CN104159583B (zh) | 2018-04-13 |
| DK2818165T3 (da) | 2019-06-03 |
| RU2014138035A (ru) | 2016-04-10 |
| EP2818165A1 (en) | 2014-12-31 |
| EP2818165B1 (en) | 2019-04-10 |
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