RU2615130C2 - Гетероциклические соединения, используемые в качестве ингибиторов pdk1 - Google Patents

Гетероциклические соединения, используемые в качестве ингибиторов pdk1 Download PDF

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RU2615130C2
RU2615130C2 RU2012118667A RU2012118667A RU2615130C2 RU 2615130 C2 RU2615130 C2 RU 2615130C2 RU 2012118667 A RU2012118667 A RU 2012118667A RU 2012118667 A RU2012118667 A RU 2012118667A RU 2615130 C2 RU2615130 C2 RU 2615130C2
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Russia
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ring
nitrogen
optionally substituted
oxygen
mmol
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RU2012118667A
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Russian (ru)
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RU2012118667A (ru
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Джозеф АРНДТ
Тимоти ЧАНЬ
Кевин ГУКИАН
Гианасамбандам КУМАРАВЕЛ
Вен-Чернг Ли
Эдвард Инь-Шиан Лин
Дэниел СКОТТ
Лихун Сунь
Джермейн Томас
ВЛОТЕН Курт ВАН
Дэпин ВАН
Лей ЧЖАН
Дэниел ЭРЛАНСОН
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Милленниум Фармасьютикалз, Инк
Санесис Фармасьютикалз, Инк.
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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