RU2577964C2 - Полипептиды - Google Patents
Полипептиды Download PDFInfo
- Publication number
- RU2577964C2 RU2577964C2 RU2013102953/10A RU2013102953A RU2577964C2 RU 2577964 C2 RU2577964 C2 RU 2577964C2 RU 2013102953/10 A RU2013102953/10 A RU 2013102953/10A RU 2013102953 A RU2013102953 A RU 2013102953A RU 2577964 C2 RU2577964 C2 RU 2577964C2
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- RU
- Russia
- Prior art keywords
- seq
- polypeptide
- albumin
- albumin binding
- binding polypeptide
- Prior art date
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- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39928510P | 2010-07-09 | 2010-07-09 | |
| US61/399,285 | 2010-07-09 | ||
| US40356110P | 2010-09-17 | 2010-09-17 | |
| US61/403,561 | 2010-09-17 | ||
| PCT/EP2011/061623 WO2012004384A2 (en) | 2010-07-09 | 2011-07-08 | Polypeptides |
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| RU2013102953A RU2013102953A (ru) | 2014-08-20 |
| RU2577964C2 true RU2577964C2 (ru) | 2016-03-20 |
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| RU2013102953/10A RU2577964C2 (ru) | 2010-07-09 | 2011-07-08 | Полипептиды |
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| JP (2) | JP5827994B2 (https=) |
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| CA (1) | CA2804002C (https=) |
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| NZ (1) | NZ604805A (https=) |
| PL (2) | PL2590993T3 (https=) |
| RU (1) | RU2577964C2 (https=) |
| TR (1) | TR201809437T4 (https=) |
| WO (1) | WO2012004384A2 (https=) |
| ZA (1) | ZA201300994B (https=) |
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| WO2024263059A1 (ru) * | 2023-06-21 | 2024-12-26 | Общество С Ограниченной Ответственностью "Герофарм" | Гибридные белки-предшественники пептидных иммуногенов ‒ компонентов вакцины против covid-19 |
| US12485402B2 (en) | 2020-02-05 | 2025-12-02 | Eli Lilly And Company | Three resin reactors in series peptide synthesizer |
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| PT2621515T (pt) | 2010-09-28 | 2017-07-12 | Aegerion Pharmaceuticals Inc | Polipéptido quimérico de leptina de foca-ser humano com solubilidade aumentada |
| BR112013029892A2 (pt) | 2011-05-21 | 2016-12-20 | Macrogenics Inc | polipeptídeo, molécula de ligação a antígeno, diacorpo e uso de uma porção polipeptídica de uma proteína de ligação a soro desimunizada |
| CN103957926B (zh) * | 2011-07-08 | 2018-07-03 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| JP6006309B2 (ja) | 2011-07-08 | 2016-10-12 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド |
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| AU2014230018B2 (en) * | 2013-03-15 | 2018-02-22 | Affibody Ab | New polypeptides |
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| US20160361415A1 (en) | 2015-05-28 | 2016-12-15 | Armo Biosciences, Inc. | Methods of Using Interleukin-10 for Treating Diseases and Disorders |
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| KR102806328B1 (ko) | 2017-07-11 | 2025-05-14 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
| CN111164104A (zh) | 2017-08-09 | 2020-05-15 | 麻省理工学院 | 白蛋白结合肽缀合物及其方法 |
| CN108362873B (zh) * | 2018-02-13 | 2021-06-01 | 苏州仁端生物医药科技有限公司 | 一种镉离子检测试剂盒及其应用 |
| JP7545894B2 (ja) * | 2018-03-13 | 2024-09-05 | アフィボディ アクティエボラーグ | 新規足場に基づくポリペプチド |
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| US20230190881A1 (en) | 2020-02-17 | 2023-06-22 | Biotest Ag | Subcutaneous administration of factor viii |
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| CN113416683B (zh) * | 2021-06-01 | 2023-05-02 | 南昌大学 | 一种大肠杆菌Nissle 1917基因工程菌及其制备方法和应用 |
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2012
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2013
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2015
- 2015-10-16 JP JP2015204395A patent/JP6486810B2/ja active Active
- 2015-12-01 US US14/955,647 patent/US10329331B2/en active Active
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2019
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| WO2024263059A1 (ru) * | 2023-06-21 | 2024-12-26 | Общество С Ограниченной Ответственностью "Герофарм" | Гибридные белки-предшественники пептидных иммуногенов ‒ компонентов вакцины против covid-19 |
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