RU2472539C2 - Способы и устройства для доставки препарата десмопрессина - Google Patents

Способы и устройства для доставки препарата десмопрессина Download PDF

Info

Publication number
RU2472539C2
RU2472539C2 RU2010108304/14A RU2010108304A RU2472539C2 RU 2472539 C2 RU2472539 C2 RU 2472539C2 RU 2010108304/14 A RU2010108304/14 A RU 2010108304/14A RU 2010108304 A RU2010108304 A RU 2010108304A RU 2472539 C2 RU2472539 C2 RU 2472539C2
Authority
RU
Russia
Prior art keywords
desmopressin
patient
skin
flow rate
concentration
Prior art date
Application number
RU2010108304/14A
Other languages
English (en)
Russian (ru)
Other versions
RU2010108304A (ru
Inventor
Самьюэл ХЕРШКОВИТЦ
Сеймор Файн
Original Assignee
Аллерган, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аллерган, Инк. filed Critical Аллерган, Инк.
Publication of RU2010108304A publication Critical patent/RU2010108304A/ru
Application granted granted Critical
Publication of RU2472539C2 publication Critical patent/RU2472539C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/482Varying injection pressure, e.g. by varying speed of injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
RU2010108304/14A 2007-08-06 2008-08-06 Способы и устройства для доставки препарата десмопрессина RU2472539C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95415907P 2007-08-06 2007-08-06
US60/954,159 2007-08-06
PCT/US2008/072290 WO2009021007A1 (en) 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery

Publications (2)

Publication Number Publication Date
RU2010108304A RU2010108304A (ru) 2011-09-20
RU2472539C2 true RU2472539C2 (ru) 2013-01-20

Family

ID=39817151

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010108304/14A RU2472539C2 (ru) 2007-08-06 2008-08-06 Способы и устройства для доставки препарата десмопрессина

Country Status (10)

Country Link
US (3) US8399410B2 (OSRAM)
EP (1) EP2197532A1 (OSRAM)
JP (3) JP5451613B2 (OSRAM)
KR (2) KR20140143461A (OSRAM)
CN (1) CN101801452B (OSRAM)
AU (1) AU2008283929B2 (OSRAM)
BR (1) BRPI0814986A2 (OSRAM)
CA (2) CA2695634C (OSRAM)
RU (1) RU2472539C2 (OSRAM)
WO (1) WO2009021007A1 (OSRAM)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6445933A (en) * 1987-08-12 1989-02-20 Nissan Motor Control device in internal combustion engine with automatic gear
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
CN101528830A (zh) 2006-07-10 2009-09-09 麦德医像公司 超弹性环氧水凝胶
CN101801452B (zh) 2007-08-06 2014-10-22 阿勒根公司 用于去氨加压素药物给送的设备
JP2011505520A (ja) 2007-12-03 2011-02-24 メディパックス インコーポレイテッド 流体計量供給装置
LT3225249T (lt) * 2008-05-21 2019-01-10 Ferring B.V. Burnoje disperguojamas desmopresinas, skirtas pirminio miego periodo, nepertraukiamo nikturija, pailginimui
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
ES2638815T5 (en) 2009-06-18 2025-06-26 Acerus Pharmaceuticals Usa Llc Safe desmopressin administration
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
JP2014518278A (ja) 2011-06-29 2014-07-28 アラーガン インコーポレイテッド 蕁麻疹の治療に用いるアルカフタジン
US9474685B2 (en) * 2011-09-28 2016-10-25 Sure-Shot Medical Device Inc. Apparatus for localized dermatological treatment
WO2013103389A1 (en) 2012-01-04 2013-07-11 Wellesley Pharmaceuticals, Llc Delayed-release formulation for reducing the frequency of urination and method of use thereof
US10278925B2 (en) 2012-01-04 2019-05-07 Wellesley Pharmaceuticals, Llc Delayed-release formulations, methods of making and use thereof
WO2013129028A1 (ja) * 2012-02-29 2013-09-06 凸版印刷株式会社 針状体および針状体の製造方法
CN104302689A (zh) 2012-03-14 2015-01-21 麦德医像公司 含有过量活性分子的智能聚合物材料
WO2014018223A1 (en) * 2012-07-27 2014-01-30 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for bedwetting and method of use thereof
JP6522523B2 (ja) * 2013-02-28 2019-05-29 ソレント・セラピューティクス・インコーポレイテッド 経皮的薬物送達装置
CA2919194A1 (en) * 2013-07-23 2015-01-29 Allergan, Inc. Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor
ES2910361T3 (es) * 2013-07-23 2022-05-12 Serenity Pharmaceuticals Llc Composiciones que comprenden desmopresina en combinación con un agonista del receptor adrenérgico beta-3
JPWO2016006409A1 (ja) * 2014-07-09 2017-04-27 凸版印刷株式会社 液剤注入装置
WO2016039418A1 (ja) * 2014-09-11 2016-03-17 久光製薬株式会社 マイクロニードルデバイス
CN106999538A (zh) * 2014-11-20 2017-08-01 阿勒根公司 包含去氨加压素与α‑肾上腺素能受体拮抗剂组合的方法和组合物
KR101708767B1 (ko) 2016-09-07 2017-02-21 주식회사 파마리서치프로덕트 인공피부용 약물충전장치
AU2017376502B2 (en) 2016-12-16 2023-10-05 Vivasor, Inc. Method for administering a medicament suitable for treating a migraine or cluster headache
USD836774S1 (en) 2016-12-16 2018-12-25 Sorrento Therapeutics, Inc. Cartridge for a fluid delivery apparatus
USD819197S1 (en) 2016-12-16 2018-05-29 Kimberly-Clark Worldwide, Inc. Fluid delivery apparatus
CN114681787A (zh) 2016-12-16 2022-07-01 索伦托治疗有限公司 具有控制器组件的流体递送装置及其使用方法
JP6977258B2 (ja) * 2016-12-20 2021-12-08 株式会社リコー 中空構造体
KR101858394B1 (ko) * 2017-03-31 2018-05-15 부산대학교 산학협력단 경피형 약물 전달 패치, 경피형 약물 전달 시스템 및 약물 투여량을 모니터링하는 방법
JP6884037B2 (ja) * 2017-05-29 2021-06-09 株式会社ジェイメック パルス電圧治療装置
CN107260245A (zh) * 2017-07-08 2017-10-20 徐欣欣 一种凝血功能障碍患者的紧急辅助止血装置
CN118078835A (zh) * 2017-12-21 2024-05-28 杏林制药株式会社 用于夜间尿频的治疗剂
KR101891465B1 (ko) * 2018-03-16 2018-08-23 부산대학교 산학협력단 경피형 약물 전달 패치, 경피형 약물 전달 시스템 및 약물 투여량을 모니터링하는 방법
CN108939284B (zh) * 2018-08-16 2023-08-08 厦门薇针医药科技有限公司 可溶解微针注射装置
DE102019105694A1 (de) * 2019-03-06 2020-09-10 Lts Lohmann Therapie-Systeme Ag Mikronadelarray aufweisend ein wärmeerzeugendes Element
CN111939454A (zh) * 2019-05-16 2020-11-17 (株)我丽美业有限公司 一种用于诱导药物吸收的皮肤刺激仪
WO2021142160A1 (en) * 2020-01-10 2021-07-15 The Regents Of The University Of California Gelatin-based microneedle patch for minimally-invasive extraction of bodily fluids
KR102720559B1 (ko) * 2023-04-04 2024-10-24 (주)이지템 에너지 기반 디바이스

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0278474A1 (en) * 1987-02-10 1988-08-17 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US5848991A (en) * 1990-12-13 1998-12-15 Elan Medical Technologies Limited Athlone, Co. Intradermal drug delivery device and method for intradermal delivery of drugs
US20020016562A1 (en) * 1996-06-18 2002-02-07 Michel J. N. Cormier Device and method for enhancing transdermal flux of agents being delivered or sampled
WO2004041153A2 (en) * 2002-05-07 2004-05-21 Fein Seymour H Pharmaceutical composition including low dosages of desmopressin
WO2005041871A2 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
RU2282468C2 (ru) * 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316893A (en) 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US3989816A (en) 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4285858A (en) 1979-10-30 1981-08-25 Mt. Sinai School Of Medicine Of The City University Of N.Y. Vasopressin analogs
US4263283A (en) 1980-05-16 1981-04-21 Ferring Pharmaceuticals, Inc. Method for prophylaxis and/or treatment of sickle cell disease
US4557934A (en) 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
SE8306367L (sv) 1983-11-18 1985-05-19 Ferring Ab Antidiuretiskt verkande farmaceutiskt preparat
US4863737A (en) 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US4588580B2 (en) 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US4698062A (en) * 1985-10-30 1987-10-06 Alza Corporation Medical device for pulsatile transdermal delivery of biologically active agents
IE60941B1 (en) 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US5032109A (en) * 1987-02-10 1991-07-16 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US4783450A (en) 1987-04-13 1988-11-08 Warner-Lambert Company Use of commercial lecithin as skin penetration enhancer
US5091186A (en) 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
SE9101022D0 (sv) 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US6746678B1 (en) 1991-02-22 2004-06-08 Howard K. Shapiro Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments
US5464387A (en) 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
US5298256A (en) 1992-04-28 1994-03-29 Corint, Ltd. Desmopressin buccal patch composition
US5534496A (en) 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
CA2090738C (en) 1993-02-24 1996-05-21 Hema-Quebec Use of paf
SE9300937L (sv) 1993-03-19 1994-09-20 Anne Fjellestad Paulsen Komposition för oral administrering av peptider
SE501677C2 (sv) 1993-06-18 1995-04-10 Ferring Bv Biologiskt aktiva vasopressinanaloger, farmaceutiska preparat innehållande dem samt deras användning för framställning av läkemedel
US5482931A (en) 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
US5985835A (en) 1993-12-23 1999-11-16 Ferring B.V. Desmopressin for nocturia, incontinence and enuresis
US5674850A (en) 1993-12-23 1997-10-07 Ferring Ab High purity desmopressin produced in large single batches
US5500413A (en) 1993-06-29 1996-03-19 Ferring Ab Process for manufacture of 1-deamino-8-D-arginine vasopressin
PT710243E (pt) 1993-06-29 2000-11-30 Ferring Bv Sintese melhorada de peptidos ciclicos.
NZ268442A (en) 1993-06-29 1996-09-25 Ferring Bv Aqueous composition of desmopressin for nasal spray administration
US5707648A (en) 1993-11-17 1998-01-13 Lds Technologies, Inc. Transparent liquid for encapsulated drug delivery
SE9400918L (sv) 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
DE19518932C2 (de) 1994-05-23 1999-03-18 Samsung Electro Mech Vorrichtung zur Perforation der Haut für die Vorbereitung einer transdermalen Medikation
KR0134152B1 (ko) 1994-05-23 1998-04-14 이형도 의약품 투여용 피부흠집 형성장치
GB9410388D0 (en) 1994-05-24 1994-07-13 Erba Carlo Spa Method for the preparation of 9-amino camptothecin
SE518619C2 (sv) 1994-12-09 2002-10-29 Gs Dev Ab Komposition för reglerad frisättning innehållande monokaproin
GB9502879D0 (en) 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
IL113459A (en) 1995-04-23 2000-07-16 Electromagnetic Bracing System Electrophoretic cuff apparatus
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
US5843016A (en) 1996-03-18 1998-12-01 Physion S.R.L. Electromotive drug administration for treatment of acute urinary outflow obstruction
TW411277B (en) 1996-05-13 2000-11-11 Hisamitsu Pharmaceutical Co Percutaneous tape preparation containing fentanyl
US5763398A (en) 1996-06-20 1998-06-09 Ferring B.V. Nasal administration of desmopressin
US5922680A (en) 1996-10-23 1999-07-13 Ferring, B.V. Stabilized composition for oral administration of peptides
SE9604341D0 (sv) 1996-11-26 1996-11-26 Ferring Bv Hepta-peptide oxytocin analogue
FR2758195B1 (fr) 1997-01-09 1999-02-26 Sgs Thomson Microelectronics Coprocesseur d'arithmetique modulaire comprenant deux circuits de multiplication operant en parallele
US5985385A (en) 1997-05-23 1999-11-16 No Fire Technologies, Inc. Fire and heat protection wrap for conduits, cable trays, other electrical transmission lines and gas and oil pipelines
US5932745A (en) 1997-07-30 1999-08-03 American Home Products Corporation Process for converting propargylic amine-N-oxides to enaminones
US6511974B1 (en) 1997-07-30 2003-01-28 Wyeth Tricyclic vasopressin agonists
US6194407B1 (en) 1997-07-30 2001-02-27 American Home Products Corporation Tricyclic pyrido vasopressin agonists
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US7153845B2 (en) 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US20040018241A1 (en) 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US6322532B1 (en) 1998-06-24 2001-11-27 3M Innovative Properties Company Sonophoresis method and apparatus
US7138393B2 (en) 1998-07-24 2006-11-21 Wyeth Biologically active vasopressin agonist metabolites
US6090803A (en) 1998-07-24 2000-07-18 American Home Products Corporation Tricyclic vasopressin agonists
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US20060025387A1 (en) 1998-12-23 2006-02-02 Cytoscan Sciences Llc Compositions and methods for the treatment of disorders of the central and peripheral nervous systems
US6344451B1 (en) 1999-02-04 2002-02-05 American Home Products Pyrrolobenzodiazepine carboxyamide vasopressin agonists
US6235900B1 (en) 1999-02-04 2001-05-22 American Home Products Corporation Tricyclic pyridine N-oxides vasopressin agonists
US6620807B1 (en) 1999-02-04 2003-09-16 Wyeth Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists
US6297234B1 (en) 1999-02-04 2001-10-02 American Home Products Corporation Arylthiophene vasopressin agonists
HK1041228A1 (zh) 1999-02-18 2002-07-05 Biovalve Technologies, Inc. 电活动孔
AR014640A1 (es) 1999-02-23 2001-03-28 Univ Nac Quilmes UNA COMPOSICíoN FARMACÉUTICA INHIBIDORA DE LA DISEMINACIoN METASTÁSICA DURANTE LA CIRUGíA DE UN TUMOR CANCEROSO, UN PROCEDIMENTO DE PREPARACIoN Y UN KIT PARA UNA FORMULACIoN INYECTABLE.
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US7060708B2 (en) 1999-03-10 2006-06-13 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
GB2355454A (en) 1999-10-20 2001-04-25 Ferring Bv Antidiuretic agents
US6558695B2 (en) 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
GB0000079D0 (en) 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
CA2396569C (en) 2000-01-07 2010-03-23 Biovalve Technologies, Inc. Injection device
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
AT409081B (de) 2000-02-16 2002-05-27 Gebro Pharma Gmbh Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung
GB0015601D0 (en) 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
TWI287984B (en) 2000-10-17 2007-10-11 Wyeth Corp Pharmaceutical composition for modulating bladder function
KR20030071780A (ko) 2000-11-30 2003-09-06 바이오밸브 테크놀로지스, 인코포레이티드 주입기
ES2574917T3 (es) 2000-11-30 2016-06-23 Valeritas, Inc. Sistemas y procedimientos de suministro y medición de fluido
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
AU2002231207A1 (en) 2000-12-21 2002-07-01 Biovalve Technologies, Inc. Microneedle array systems
ATE364380T1 (de) 2001-03-16 2007-07-15 Alza Corp Transdermales pflaster zur verabreichung von fentanyl
US7022699B2 (en) 2001-04-12 2006-04-04 Wyeth Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators
DE60222879T2 (de) 2001-04-12 2008-07-24 Wyeth Cyclohexylphenyl vasopressin agonisten
DE60218646T2 (de) 2001-04-12 2007-11-22 Wyeth N-biphenylcarbonyl- und n-phenylpyridylcarbonyl substituierte bi- und tricyclische azepine und diazepine als vasopressin-agonisten
US7615234B2 (en) 2001-09-11 2009-11-10 Glide Pharmaceutical Technologies Limited Drug delivery technology
DE60229404D1 (de) 2001-09-13 2008-11-27 Kissei Pharmaceutical Kristalle eines hydroxynorephedrinderivats
US6723077B2 (en) 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
US6893655B2 (en) 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
JP4075064B2 (ja) 2001-11-16 2008-04-16 アステラス製薬株式会社 4,4−ジフルオロ−1,2,3,4−テトラヒドロ−5h−1−ベンゾアゼピン誘導体又はその塩
PT1501534E (pt) * 2002-05-07 2006-09-29 Ferring Bv Formulacoes farmaceuticas
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
AR040302A1 (es) * 2002-06-28 2005-03-23 Alza Corp Dispositivos para la liberacion transdermica de farmacos, que presentan microprotrusiones recubiertas
GB2421689B (en) 2002-08-05 2007-03-07 Caretek Medical Ltd Drug delivery system
US20040115167A1 (en) 2002-09-30 2004-06-17 Michel Cormier Drug delivery device and method having coated microprojections incorporating vasoconstrictors
CA2501389C (en) 2002-10-09 2013-01-08 Toray Industries, Inc. Remedies or preventives for frequent urination or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group
US7383084B2 (en) 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
DE10259934B3 (de) 2002-12-20 2004-10-14 H.C. Starck Gmbh Verfahren zur Herstellung von Formteilen aus Niob oder Tantal durch elektrochemisches Ätzen und so erhältliche Formteile
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
EP1612819B1 (en) 2003-03-31 2019-06-12 Subaru Corporation Organic electrolyte capacitor
AU2004234258B2 (en) 2003-04-28 2009-04-09 Tacurion 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof
US20060193825A1 (en) 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US7094545B2 (en) 2003-04-30 2006-08-22 Ferring Bv Pharmaceutical composition as solid dosage form and method for manufacturing thereof
PL1638468T3 (pl) 2003-06-30 2008-01-31 Alza Corp Sposób powlekania mikrowystępów do przekłuwania skóry
DE60301351T2 (de) 2003-07-25 2006-01-19 Ferring B.V. Pharmazeutische Desmopressin-Zubereitung als feste Darreichungsform und Methode zu ihrer Herstellung
CN1826099B (zh) 2003-07-25 2010-06-09 凡林有限公司 固体剂型药物组合物及其制造方法
AU2004264319A1 (en) * 2003-08-04 2005-02-24 Alza Corporation Method and device for enhancing transdermal agent flux
US6930932B2 (en) 2003-08-27 2005-08-16 Hewlett-Packard Development Company, L.P. Data signal reception latch control using clock aligned relative to strobe signal
BRPI0415466A (pt) 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
EP1680154B1 (en) 2003-10-31 2012-01-04 ALZA Corporation Self-actuating applicator for microprojection array
AU2003287591C1 (en) 2003-11-10 2009-12-10 Serenity Pharmaceuticals Llc Pharmaceutical compositions including low dosages of desmopressin
JP2005152180A (ja) * 2003-11-25 2005-06-16 Nano Device & System Research Inc インスリン投与用マイクロニードル
US7018653B2 (en) 2003-12-29 2006-03-28 Ferring B.V. Method for preparing solid dosage form of desmopressin
EP1706176A4 (en) 2004-01-09 2008-06-25 Alza Corp METHOD AND SYSTEM FOR FREQUENCY-ASSISTED TRANSDERMAL-BASED TRANSDERMAL AGENT DELIVERY
DK1797109T3 (en) 2004-09-09 2016-04-11 Yeda Res & Dev MIXTURES OF POLYPEPTIDES, compositions containing them and methods for their preparation, and uses thereof
JP4556113B2 (ja) 2004-09-09 2010-10-06 株式会社ダイフク スタッカークレーン
US7097776B2 (en) 2004-10-22 2006-08-29 Hewlett-Packard Development Company, L.P. Method of fabricating microneedles
US20080009800A1 (en) 2004-12-02 2008-01-10 Nickel Janice H Transdermal drug delivery device
FR2879273A1 (fr) 2004-12-09 2006-06-16 Hutchinson Sa Dispositif anti-vibratoire hydraulique a entretoise
US7180274B2 (en) 2004-12-10 2007-02-20 Aimtron Technology Corp. Switching voltage regulator operating without a discontinuous mode
KR20070100820A (ko) * 2005-01-31 2007-10-11 가부시키가이샤 바이오세렌택 경피 흡수 제제, 경피 흡수 제제 유지 시트 및 경피 흡수제제 유지 용구
MX2007009635A (es) 2005-02-10 2007-09-25 Orexo Ab Nuevas composiciones farmaceuticas utiles en la administracion transmucosa de farmacos.
CN101175740A (zh) 2005-04-22 2008-05-07 惠氏公司 二氢苯并呋喃衍生物和其用途
BRPI0610046A2 (pt) 2005-04-22 2010-05-25 Wyeth Corp derivados de benzodioxano e benzodioxolano e usos destes
US7856263B2 (en) 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
RU2007139541A (ru) 2005-04-22 2009-05-27 Вайет (Us) Производные хромана и хромена и их применение
CN101203218A (zh) 2005-04-22 2008-06-18 惠氏公司 苯并呋喃基链烷胺衍生物和其作为5-ht2c激动剂的用途
CN101203216A (zh) 2005-04-22 2008-06-18 惠氏公司 二氢苯并呋喃衍生物及其用途
US20060258712A1 (en) 2005-04-24 2006-11-16 Wyeth Methods for modulating bladder function
WO2006138719A2 (en) 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
EP1904158B1 (en) 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
JP2007152745A (ja) 2005-12-05 2007-06-21 Tombow Pencil Co Ltd 加圧ペン
WO2007083323A2 (en) 2006-01-23 2007-07-26 Panacea Biotec Limited. Modified release oral dosage form comprising desmopressin
US8101114B2 (en) 2006-05-01 2012-01-24 Georgia Tech Research Corporation Particle based molding
CN101801452B (zh) 2007-08-06 2014-10-22 阿勒根公司 用于去氨加压素药物给送的设备
US20100160214A1 (en) 2008-12-22 2010-06-24 Serenity Pharmaceuticals Corporation Desmopressin composition
NZ593613A (en) * 2008-12-22 2013-02-22 Allergan Inc Intranasal desmopressin administration
ES2638815T5 (en) 2009-06-18 2025-06-26 Acerus Pharmaceuticals Usa Llc Safe desmopressin administration

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0278474A1 (en) * 1987-02-10 1988-08-17 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5848991A (en) * 1990-12-13 1998-12-15 Elan Medical Technologies Limited Athlone, Co. Intradermal drug delivery device and method for intradermal delivery of drugs
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US20020016562A1 (en) * 1996-06-18 2002-02-07 Michel J. N. Cormier Device and method for enhancing transdermal flux of agents being delivered or sampled
RU2282468C2 (ru) * 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием
WO2004041153A2 (en) * 2002-05-07 2004-05-21 Fein Seymour H Pharmaceutical composition including low dosages of desmopressin
WO2005041871A2 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MICHEL CORMIER et al., Transdermaldelivery of desmopressin using a coated microneedle array patch system., Journal of Controlled Release Volume 97, Issue 3, 7 July 2004, Pages 503-511, реферат, найдено из Интернет на сайте: http://www.sciencedirect.com/science/article/pii/S0168365904001713. *
MICHEL CORMIER et al., Transdermaldelivery of desmopressin using a coated microneedle array patch system., Journal of Controlled Release Volume 97, Issue 3, 7 July 2004, Pages 503-511, реферат, найдено из Интернет на сайте: http://www.sciencedirect.com/science/article/pii/S0168365904001713. NAKAKURA M, et al., Prolongation of antidiuretic response to desmopressin acetate by iontophoretic transdermal delivery in rats., Biol Pharm Bull. 1997 May; 20(5):537-40., реферат, найдено из Интернет на сайте: http://www.ncbi.nlm.nih.gov/pubmed/9178935. *
NAKAKURA M, et al., Prolongation of antidiuretic response to desmopressin acetate by iontophoretic transdermal delivery in rats., Biol Pharm Bull. 1997 May; 20(5):537-40., реферат, найдено из Интернет на сайте: http://www.ncbi.nlm.nih.gov/pubmed/9178935. *

Also Published As

Publication number Publication date
US20160303185A1 (en) 2016-10-20
US20140058313A1 (en) 2014-02-27
JP5891216B2 (ja) 2016-03-22
JP2014138843A (ja) 2014-07-31
US9375530B2 (en) 2016-06-28
CN101801452A (zh) 2010-08-11
AU2008283929B2 (en) 2013-10-10
CN101801452B (zh) 2014-10-22
KR20140143461A (ko) 2014-12-16
KR101522747B1 (ko) 2015-05-26
JP2010535589A (ja) 2010-11-25
US8399410B2 (en) 2013-03-19
JP5451613B2 (ja) 2014-03-26
KR20100103452A (ko) 2010-09-27
EP2197532A1 (en) 2010-06-23
CA2988753A1 (en) 2009-02-12
WO2009021007A1 (en) 2009-02-12
BRPI0814986A2 (pt) 2015-02-03
RU2010108304A (ru) 2011-09-20
CA2695634A1 (en) 2009-02-12
JP2016093515A (ja) 2016-05-26
CA2695634C (en) 2018-01-23
AU2008283929A1 (en) 2009-02-12
US20090042970A1 (en) 2009-02-12

Similar Documents

Publication Publication Date Title
RU2472539C2 (ru) Способы и устройства для доставки препарата десмопрессина
JP7137234B2 (ja) 口を介する連続的薬物送達のためのデバイスおよび方法
US11471424B2 (en) Biosynchronous transdermal drug delivery
Langer Implantable controlled release systems
JP2003500119A (ja) 小分子インスリン様物質の投薬装置及び投与法
JP2005511120A (ja) 皮膚デポからの医薬品の制御された熱誘導迅速送達
Buckles Biomaterials for drug delivery systems
Chandrasekaran et al. Therapeutic systems and controlled drug delivery
Zaffaroni Applications of polymers in rate-controlled drug delivery
Katoch et al. A Review on Glucose-Responsive Microneedle Patches for Diabetes Treatment
JPH07255845A (ja) ジェットインジェクション経皮吸収装置及び経皮吸収促進方法
Owayez et al. New Dosage Form of Insulin
WO2011033328A1 (en) Insulin dosing micro-infusion device useful for the treatment of diabetes
BODY effects, with side effects tending to predominate early in the inter-val following the dose. Later, the concentration of drug falls too
JP2008055197A (ja) 吐出方法及び吐出用液体組成物

Legal Events

Date Code Title Description
PC41 Official registration of the transfer of exclusive right

Effective date: 20180301

MM4A The patent is invalid due to non-payment of fees

Effective date: 20190807