RU2460540C2 - Антитела, связывающиеся с внеклеточным доменом тирозинкиназного рецептора (alk) - Google Patents
Антитела, связывающиеся с внеклеточным доменом тирозинкиназного рецептора (alk) Download PDFInfo
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- RU2460540C2 RU2460540C2 RU2008146922/10A RU2008146922A RU2460540C2 RU 2460540 C2 RU2460540 C2 RU 2460540C2 RU 2008146922/10 A RU2008146922/10 A RU 2008146922/10A RU 2008146922 A RU2008146922 A RU 2008146922A RU 2460540 C2 RU2460540 C2 RU 2460540C2
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| AU2007246144B2 (en) * | 2006-04-28 | 2012-12-06 | Delenex Therapeutics Ag | Antibodies binding to the extracellular domain of the Receptor Tyrosine Kinase ALK |
| WO2008131575A2 (en) * | 2007-04-27 | 2008-11-06 | Esbatech Ag | Anti-alk antibodies suitable for treating metastatic cancers or tumors |
| US20110206691A1 (en) * | 2008-02-15 | 2011-08-25 | Mosse Yael P | Methods and Compositions for Treating Neuroblastoma |
| WO2009103061A2 (en) * | 2008-02-15 | 2009-08-20 | The Children's Hospital Of Philadelphia | Methods and compositions for identifying, diagnosing, and treating neuroblastoma |
| MX345395B (es) | 2008-06-25 | 2017-01-30 | Esbatech Alcon Biomed Res Unit | Humanizacion de anticuerpos de conejos usando una estructura de anticuerpos universal. |
| WO2009155723A2 (en) | 2008-06-25 | 2009-12-30 | Esbatech, An Alcon Biomedical Research Unit Llc | STABLE AND SOLUBLE ANTIBODIES INHIBITING TNFα |
| UY33679A (es) | 2010-10-22 | 2012-03-30 | Esbatech | Anticuerpos estables y solubles |
| JP2015527869A (ja) | 2011-08-26 | 2015-09-24 | メリマック ファーマシューティカルズ インコーポレーティッド | タンデムＦｃ二重特異性抗体 |
| WO2013067492A1 (en) | 2011-11-03 | 2013-05-10 | The Trustees Of The University Of Pennsylvania | Isolated b7-h4 specific compositions and methods of use thereof |
| WO2014138449A1 (en) | 2013-03-06 | 2014-09-12 | Merrimack Pharmaceuticals, Inc. | Anti-c-met tandem fc bispecific antibodies |
| CN104861069B (zh) * | 2014-02-21 | 2018-12-18 | 无锡傲锐东源生物科技有限公司 | 针对间变性淋巴瘤激酶的单克隆抗体1a4及其用途 |
| WO2015184231A2 (en) * | 2014-05-30 | 2015-12-03 | Kolltan Pharmaceuticals, Inc. | Regulators of anaplastic lymphoma kinase and uses thereof |
| EP3341021A4 (en) | 2015-08-27 | 2019-03-13 | Celldex Therapeutics, Inc. | ANTI-ALK ANTIBODIES AND METHOD OF USE THEREOF |
| CA2940470C (en) | 2015-09-18 | 2019-08-20 | Signpath Pharma Inc. | Treatment for glioblastoma |
| JP7017015B2 (ja) | 2015-10-13 | 2022-02-08 | エウレカ セラピューティクス インコーポレイテッド | ヒトｃｄ１９に特異的な抗体剤及びその使用 |
| RU2767209C2 (ru) | 2015-10-23 | 2022-03-16 | Еурека Терапьютикс, Инк. | Химерные конструкции антитело/т-клеточный рецептор и их применения |
| WO2017147408A1 (en) * | 2016-02-25 | 2017-08-31 | The Regents Of The University Of California | Methods for the treatment of hematologic cancer |
| IL310182A (en) | 2017-04-26 | 2024-03-01 | Eureka Therapeutics Inc ׂ A Delaware Corp | Structures of chimeric antibody/T-cell receptor and uses thereof |
| EP3749682B1 (en) * | 2018-02-09 | 2025-09-24 | Acceleron Pharma Inc. | Treating heterotopic ossification |
| IT201800009282A1 (it) * | 2018-10-09 | 2020-04-09 | Metis Prec Medicine Sb Srl | Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi |
| CN113960313B (zh) * | 2021-12-22 | 2022-04-12 | 上海思路迪医学检验所有限公司 | 一种外泌体alk融合蛋白磁免疫化学发光检测试剂盒 |
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| US21505A (en) * | 1858-09-14 | Improvement in bullet-machines | ||
| US5529925A (en) * | 1993-12-03 | 1996-06-25 | St. Jude Children's Research Hospital | Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma |
| US6696548B2 (en) * | 1993-12-03 | 2004-02-24 | St. Jude Children's Research Hospital | Antibodies for recognition of alk protein tyrosine/kinase receptor |
| CA2229043C (en) | 1995-08-18 | 2016-06-07 | Morphosys Gesellschaft Fur Proteinoptimierung Mbh | Protein/(poly)peptide libraries |
| EP0938506B1 (en) | 1996-07-16 | 2003-11-05 | Plückthun, Andreas, Prof. Dr. | Immunoglobulin superfamily domains and fragments with increased solubility |
| JPH1116250A (ja) * | 1997-06-20 | 1999-01-22 | Pioneer Electron Corp | 情報再生システム |
| DK1242457T3 (da) * | 1999-12-28 | 2004-12-20 | Esbatech Ag | Intracellulære antistoffer [intracellulære antistoffer] med defineret struktur, der er stabil i et reducerende miljö, og anvendelse deraf |
| DE60141518D1 (de) * | 2000-06-14 | 2010-04-22 | Univ Georgetown | Pleiotrophin wachstumfaktor rezeptor alk zur behandlung von proliferativen, gefässer- und neurologischen erkrankungen |
| US7417130B2 (en) | 2000-09-08 | 2008-08-26 | University Of Zurich | Collection of repeat proteins comprising repeat modules |
| CN105175535A (zh) | 2002-05-22 | 2015-12-23 | 艾斯巴技术-诺华有限责任公司 | 在胞内环境中表现出增强的稳定性的免疫球蛋白构架及其鉴定方法 |
| US7888485B2 (en) | 2003-03-26 | 2011-02-15 | Georgetown University | Anti-pleiotrophin antibodies and methods of use thereof |
| AU2005272920B2 (en) | 2004-08-10 | 2011-05-12 | Institute For Multiple Myeloma And Bone Cancer Research | Methods of regulating differentiation and treating of multiple myeloma |
| AU2007246144B2 (en) * | 2006-04-28 | 2012-12-06 | Delenex Therapeutics Ag | Antibodies binding to the extracellular domain of the Receptor Tyrosine Kinase ALK |
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| CN101443361A (zh) | 2009-05-27 |
| EP2013236B1 (en) | 2015-06-17 |
| AU2007246144A1 (en) | 2007-11-08 |
| JP5431920B2 (ja) | 2014-03-05 |
| CA2650822C (en) | 2017-03-14 |
| US8945563B2 (en) | 2015-02-03 |
| KR20080113261A (ko) | 2008-12-29 |
| EP2013236A1 (en) | 2009-01-14 |
| US7902340B2 (en) | 2011-03-08 |
| EP2604627A1 (en) | 2013-06-19 |
| IL194752A0 (en) | 2011-08-01 |
| AU2007246144B2 (en) | 2012-12-06 |
| JP2013226144A (ja) | 2013-11-07 |
| MX2008013705A (es) | 2008-11-06 |
| CA2650822A1 (en) | 2007-11-08 |
| WO2007124610A1 (en) | 2007-11-08 |
| JP2009535021A (ja) | 2009-10-01 |
| US20110159008A1 (en) | 2011-06-30 |
| HK1124619A1 (en) | 2009-07-17 |
| US20080118512A1 (en) | 2008-05-22 |
| DK2013236T3 (en) | 2015-09-21 |
| RU2008146922A (ru) | 2010-06-10 |
| CN101443361B (zh) | 2015-08-19 |
| JP5911821B2 (ja) | 2016-04-27 |
| NZ572248A (en) | 2011-08-26 |
| US20150203829A1 (en) | 2015-07-23 |
| KR101457228B1 (ko) | 2014-11-04 |
| US9512411B2 (en) | 2016-12-06 |
| ES2547248T3 (es) | 2015-10-02 |
| PL2013236T3 (pl) | 2015-12-31 |
| BRPI0710971A2 (pt) | 2011-05-31 |
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