RU2454996C2 - Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени - Google Patents
Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени Download PDFInfo
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- RU2454996C2 RU2454996C2 RU2009128213/15A RU2009128213A RU2454996C2 RU 2454996 C2 RU2454996 C2 RU 2454996C2 RU 2009128213/15 A RU2009128213/15 A RU 2009128213/15A RU 2009128213 A RU2009128213 A RU 2009128213A RU 2454996 C2 RU2454996 C2 RU 2454996C2
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- RU
- Russia
- Prior art keywords
- xanthohumol
- body weight
- use according
- active substance
- day
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/121—Ketones acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/348—Cannabaceae
- A61K36/3486—Humulus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Child & Adolescent Psychology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006062264.2 | 2006-12-22 | ||
| DE102006062264A DE102006062264A1 (de) | 2006-12-22 | 2006-12-22 | Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2009128213A RU2009128213A (ru) | 2011-01-27 |
| RU2454996C2 true RU2454996C2 (ru) | 2012-07-10 |
Family
ID=39186950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009128213/15A RU2454996C2 (ru) | 2006-12-22 | 2007-12-21 | Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100029757A1 (enExample) |
| EP (1) | EP2120906B1 (enExample) |
| JP (1) | JP5513126B2 (enExample) |
| CA (1) | CA2672155C (enExample) |
| DE (1) | DE102006062264A1 (enExample) |
| RU (1) | RU2454996C2 (enExample) |
| WO (1) | WO2008077618A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2641596T3 (en) * | 2009-11-26 | 2018-08-06 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for the treatment of liver disorders |
| US10722575B2 (en) | 2009-11-26 | 2020-07-28 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| US9221751B2 (en) | 2009-11-26 | 2015-12-29 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| US9358185B2 (en) | 2012-06-18 | 2016-06-07 | 3M Innovative Properties Company | Powder composition for air polishing the surface of hard dental tissue |
| KR20150036604A (ko) * | 2012-07-26 | 2015-04-07 | 테아-크산 아게 | 로스팅된 추출물 및 잔토휴몰을 포함하는 조성물의 용도 |
| EP2742898A1 (en) | 2012-12-17 | 2014-06-18 | 3M Innovative Properties Company | Powder jet device for dispensing a dental material |
| US9662180B2 (en) | 2012-12-17 | 2017-05-30 | 3M Innovative Properties Company | Device for dispensing a dental material with locking mechanism |
| EP2742897A1 (en) | 2012-12-17 | 2014-06-18 | 3M Innovative Properties Company | Nozzle head, hand piece and powder jet device for applying a dental material |
| US20180193287A1 (en) | 2015-07-02 | 2018-07-12 | John I. Haas, Inc. | Hops-based substance and use of the substance |
| AU2017384173A1 (en) * | 2016-12-20 | 2019-06-27 | Suntory Holdings Limited | Lipid metabolism-promoting composition including isoxanthohumol |
| CA3148455A1 (en) | 2017-07-11 | 2019-01-17 | Aquanova Ag | Solubilizate with curcumin and optionally at least one other active substance |
| PL3820527T3 (pl) | 2018-07-11 | 2024-01-03 | Aquanova Ag | Solubilizator ksantohumolu |
| EP3820527B1 (de) * | 2018-07-11 | 2023-08-23 | Aquanova AG | Xanthohumol-solubilisat |
| JP7307073B2 (ja) * | 2018-08-10 | 2023-07-11 | サントリーホールディングス株式会社 | 尿酸排出促進用組成物、urat1阻害用組成物及び血中尿酸値低下用組成物 |
| SG11202100262UA (en) * | 2018-08-10 | 2021-02-25 | Suntory Holdings Ltd | Composition for improving intestinal environment and method for improving intestinal flora |
| SG11202100264YA (en) * | 2018-08-10 | 2021-02-25 | Suntory Holdings Ltd | Composition and method for suppressing increase in blood glucose level |
| WO2020031953A1 (ja) * | 2018-08-10 | 2020-02-13 | サントリーホールディングス株式会社 | 微生物増殖抑制剤、微生物汚染防止方法、及び、飲料 |
| EP4291307A4 (en) * | 2021-02-09 | 2025-01-22 | Oregon State University | Xanthohumol derivatives and methods for making and using |
| IL310044A (en) * | 2021-07-09 | 2024-03-01 | Innox Corp | Prenylated chalcone and flavonoid compounds for use in cancer therapy |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2232016C2 (ru) * | 1996-08-30 | 2004-07-10 | эНПиэС ФАМЭСЬЮТИКЭЛС, ИНК. | Изовалерамид-антиспастическое и противосудорожное средство, экстракт из растения семейства valerianaceae или хмеля - средство для лечения симптома спастичности и способ устранения этого симптома, способ лечения патологии, снимаемой центрально-опосредованным снижением мышечного тонуса |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07285856A (ja) * | 1994-04-21 | 1995-10-31 | Hoechst Japan Ltd | 骨粗鬆症治療剤 |
| EP1223928A2 (en) | 1999-07-08 | 2002-07-24 | Patrick Thomas Prendergast | Use of flavones, coumarins and related compounds to treat infections |
| JP3293601B2 (ja) * | 1999-09-03 | 2002-06-17 | 松下電器産業株式会社 | 管球およびその製造方法 |
| AU2001246876A1 (en) * | 2000-04-10 | 2001-10-23 | Takara Bio Inc. | Remedies |
| US20040156950A1 (en) * | 2001-04-05 | 2004-08-12 | Green Martin Richard | Use of hop components in foods |
| EP1415657A4 (en) * | 2001-07-13 | 2005-09-14 | Takara Bio Inc | DRUG |
| DE10308864B4 (de) | 2003-02-28 | 2007-03-01 | Paulaner Brauerei Gmbh & Co. Kg | Neues Brauverfahren, damit gebrautes Bier und dessen Verwendung |
| EP1543834A1 (en) | 2003-12-16 | 2005-06-22 | Biodynamics | Production of hop extracts having oestrogenic and antiproliferative bioactivity |
| WO2006099015A2 (en) | 2005-03-09 | 2006-09-21 | Cardax Pharmaceuticals, Inc. | Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of proliferative disorders |
| JP2006306800A (ja) * | 2005-04-28 | 2006-11-09 | Kirin Brewery Co Ltd | ファルネソイドx受容体活性化剤 |
| KR20080063748A (ko) * | 2005-07-29 | 2008-07-07 | 바이오액티브스, 인코포레이티드 | 프레닐플라보노이드 제형 |
| CA2618613A1 (en) * | 2005-08-09 | 2007-02-22 | Metaproteomics, Llc | Protein kinase modulation by hops and acacia products |
| JP5246834B2 (ja) * | 2005-12-27 | 2013-07-24 | 独立行政法人産業技術総合研究所 | アディポネクチン産生強化剤 |
-
2006
- 2006-12-22 DE DE102006062264A patent/DE102006062264A1/de not_active Ceased
-
2007
- 2007-12-21 WO PCT/EP2007/011358 patent/WO2008077618A1/de not_active Ceased
- 2007-12-21 US US12/520,756 patent/US20100029757A1/en not_active Abandoned
- 2007-12-21 CA CA2672155A patent/CA2672155C/en not_active Expired - Fee Related
- 2007-12-21 EP EP20070857069 patent/EP2120906B1/de not_active Not-in-force
- 2007-12-21 JP JP2009541912A patent/JP5513126B2/ja not_active Expired - Fee Related
- 2007-12-21 RU RU2009128213/15A patent/RU2454996C2/ru not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2232016C2 (ru) * | 1996-08-30 | 2004-07-10 | эНПиэС ФАМЭСЬЮТИКЭЛС, ИНК. | Изовалерамид-антиспастическое и противосудорожное средство, экстракт из растения семейства valerianaceae или хмеля - средство для лечения симптома спастичности и способ устранения этого симптома, способ лечения патологии, снимаемой центрально-опосредованным снижением мышечного тонуса |
Non-Patent Citations (1)
| Title |
|---|
| РОЖАНЕЦ В.В. Хмель как компонент пива и биологически активных добавок, применяемых в наркологии. Наркология №11, ноябрь 2005, он-лайн [найдено 13.12.10] [найдено из Интернет] http//www.narkotiki.ru/narcologia_ar_6263.html. ШУЛЬПЕКОВА Ю.О. Флавоноиды расторопши в лечении заболеваний печени, РМЖ Человек и лекарство, 06.03.2004, т. 12, №5, он-лайн [найдено 13.12.10] [найдено из Интернет] http//www.rmj.ru/numbers_28.htm. ЗУЗУК Б.М. Хмель вьющийся, аналитический обзор, Провизор, №14, 2004, он-лайн [найдено 13.12.10] [найдено из Интернет] http://www.provisor.com.ua/archiye/2004/N14/art_25.php. CRISTOBAL L. MIRANDA et al, Prenylflavonoids from Hops Inhibit the Metabolic Activation of the Carcinogenic Heterocyclic Amine 2-Amino-3-methylimidazo[4,5-f]quinoline, Mediated by cDNA-Expressed Human CYP1A2, Drug Metab Dispos. 2000 Nov; №28(11), c.1297-302. он-лайн [найдено 13.12.10] [найдено из Интернет] http://dmd.aspetjournals.org/content/28/ll/1297.long. * |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2009128213A (ru) | 2011-01-27 |
| JP5513126B2 (ja) | 2014-06-04 |
| JP2010513360A (ja) | 2010-04-30 |
| CA2672155A1 (en) | 2008-07-03 |
| US20100029757A1 (en) | 2010-02-04 |
| EP2120906A1 (de) | 2009-11-25 |
| WO2008077618A1 (de) | 2008-07-03 |
| CA2672155C (en) | 2013-10-01 |
| EP2120906B1 (de) | 2015-04-22 |
| DE102006062264A1 (de) | 2008-06-26 |
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| Date | Code | Title | Description |
|---|---|---|---|
| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20131023 |
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| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20171222 |