RU2454996C2 - Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени - Google Patents

Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени Download PDF

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RU2454996C2
RU2454996C2 RU2009128213/15A RU2009128213A RU2454996C2 RU 2454996 C2 RU2454996 C2 RU 2454996C2 RU 2009128213/15 A RU2009128213/15 A RU 2009128213/15A RU 2009128213 A RU2009128213 A RU 2009128213A RU 2454996 C2 RU2454996 C2 RU 2454996C2
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xanthohumol
body weight
use according
active substance
day
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RU2009128213/15A
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RU2009128213A (ru
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Клаус ХЕЛЛЕРБРАНД (DE)
Клаус ХЕЛЛЕРБРАНД
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Йох. Барт Унд Зон Гмбх Унд Ко. Кг
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3486—Humulus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
RU2009128213/15A 2006-12-22 2007-12-21 Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени RU2454996C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006062264.2 2006-12-22
DE102006062264A DE102006062264A1 (de) 2006-12-22 2006-12-22 Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen

Publications (2)

Publication Number Publication Date
RU2009128213A RU2009128213A (ru) 2011-01-27
RU2454996C2 true RU2454996C2 (ru) 2012-07-10

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RU2009128213/15A RU2454996C2 (ru) 2006-12-22 2007-12-21 Применение ксантогумола и изоксантогумола в качестве активного вещества для профилактики и/или борьбы с заболеваниями печени

Country Status (7)

Country Link
US (1) US20100029757A1 (enExample)
EP (1) EP2120906B1 (enExample)
JP (1) JP5513126B2 (enExample)
CA (1) CA2672155C (enExample)
DE (1) DE102006062264A1 (enExample)
RU (1) RU2454996C2 (enExample)
WO (1) WO2008077618A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9221751B2 (en) 2009-11-26 2015-12-29 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
ES2441665T3 (es) * 2009-11-26 2014-02-05 Genfit Utilización de derivados de 1,3-difenilprop-2-en-1-ona para tratar trastornos hepáticos
US10722575B2 (en) 2009-11-26 2020-07-28 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
WO2013191903A1 (en) 2012-06-18 2013-12-27 3M Innovative Properties Company Powder composition for air polishing the surface of hard dental tissue
BR112015001595A2 (pt) * 2012-07-26 2018-06-19 Ta-Xan Ag composição farmacêutica, uso de um extrato torrado, e, método para intensificar um ou mais efeito (s) terapêutico (s) de xantohumol e para a produção de uma composição farmacêutica
EP2931171B1 (en) 2012-12-17 2018-08-15 3M Innovative Properties Company Device for dispensing a dental material with locking mechanism
EP2742898A1 (en) 2012-12-17 2014-06-18 3M Innovative Properties Company Powder jet device for dispensing a dental material
EP2742897A1 (en) 2012-12-17 2014-06-18 3M Innovative Properties Company Nozzle head, hand piece and powder jet device for applying a dental material
US20180193287A1 (en) 2015-07-02 2018-07-12 John I. Haas, Inc. Hops-based substance and use of the substance
WO2018117041A1 (ja) * 2016-12-20 2018-06-28 サントリーホールディングス株式会社 イソキサントフモールを含む脂質代謝促進用組成物
ES2960296T3 (es) 2017-07-11 2024-03-04 Aquanova Ag Solubilizado con curcumina y boswelia y xantohumol
HRP20231146T1 (hr) * 2018-07-11 2024-01-05 Aquanova Ag Solubilizat ksantohumola
SG11202100265XA (en) * 2018-08-10 2021-02-25 Suntory Holdings Ltd Composition for promoting uric acid excretion, composition for inhibiting urat1 and composition for lowering blood uric acid level
EP3834629A4 (en) * 2018-08-10 2022-04-27 Suntory Holdings Limited COMPOSITION AND METHOD OF SUPPRESSING RAISED BLOOD SUGAR LEVELS
US20210322369A1 (en) * 2018-08-10 2021-10-21 Suntory Holdings Limited Composition for improving intestinal environment and method for improving intestinal flora
CN112584709A (zh) * 2018-08-10 2021-03-30 三得利控股株式会社 微生物增殖抑制剂、微生物污染防止方法及饮料
EP4291307A4 (en) 2021-02-09 2025-01-22 Oregon State University Xanthohumol derivatives and methods for making and using
EP4366723A4 (en) * 2021-07-09 2025-06-11 Innox Corp. COMPOSITIONS OF FLAVONOID AND PRENYLATED CHALCONES FOR USE IN THE TREATMENT OF CANCER

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2232016C2 (ru) * 1996-08-30 2004-07-10 эНПиэС ФАМЭСЬЮТИКЭЛС, ИНК. Изовалерамид-антиспастическое и противосудорожное средство, экстракт из растения семейства valerianaceae или хмеля - средство для лечения симптома спастичности и способ устранения этого симптома, способ лечения патологии, снимаемой центрально-опосредованным снижением мышечного тонуса

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07285856A (ja) 1994-04-21 1995-10-31 Hoechst Japan Ltd 骨粗鬆症治療剤
AU6174900A (en) 1999-07-08 2001-01-30 Patrick T. Prendergast Use of flavones, coumarins and related compounds to treat infections
JP3293601B2 (ja) * 1999-09-03 2002-06-17 松下電器産業株式会社 管球およびその製造方法
EP1277473A4 (en) * 2000-04-10 2005-12-28 Takara Bio Inc REMEDIES
US20040156950A1 (en) * 2001-04-05 2004-08-12 Green Martin Richard Use of hop components in foods
US20040219238A1 (en) * 2001-07-13 2004-11-04 Eiji Nishiyama Remedies
DE10308864B4 (de) 2003-02-28 2007-03-01 Paulaner Brauerei Gmbh & Co. Kg Neues Brauverfahren, damit gebrautes Bier und dessen Verwendung
EP1543834A1 (en) 2003-12-16 2005-06-22 Biodynamics Production of hop extracts having oestrogenic and antiproliferative bioactivity
EP1861109A2 (en) * 2005-03-09 2007-12-05 Cardax Pharmaceuticals, Inc. Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of proliferative disorders
JP2006306800A (ja) * 2005-04-28 2006-11-09 Kirin Brewery Co Ltd ファルネソイドｘ受容体活性化剤
EP1909584A4 (en) * 2005-07-29 2010-07-07 Bioactives Inc PRENYLFLAVONOID FORMULATIONS
EP2248532A1 (en) * 2005-08-09 2010-11-10 Metaproteomics, LLP Protein kinase modulation by hops and acacia products cross-reference to related applications
JP5246834B2 (ja) * 2005-12-27 2013-07-24 独立行政法人産業技術総合研究所 アディポネクチン産生強化剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2232016C2 (ru) * 1996-08-30 2004-07-10 эНПиэС ФАМЭСЬЮТИКЭЛС, ИНК. Изовалерамид-антиспастическое и противосудорожное средство, экстракт из растения семейства valerianaceae или хмеля - средство для лечения симптома спастичности и способ устранения этого симптома, способ лечения патологии, снимаемой центрально-опосредованным снижением мышечного тонуса

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
РОЖАНЕЦ В.В. Хмель как компонент пива и биологически активных добавок, применяемых в наркологии. Наркология №11, ноябрь 2005, он-лайн [найдено 13.12.10] [найдено из Интернет] http//www.narkotiki.ru/narcologia_ar_6263.html. ШУЛЬПЕКОВА Ю.О. Флавоноиды расторопши в лечении заболеваний печени, РМЖ Человек и лекарство, 06.03.2004, т. 12, №5, он-лайн [найдено 13.12.10] [найдено из Интернет] http//www.rmj.ru/numbers_28.htm. ЗУЗУК Б.М. Хмель вьющийся, аналитический обзор, Провизор, №14, 2004, он-лайн [найдено 13.12.10] [найдено из Интернет] http://www.provisor.com.ua/archiye/2004/N14/art_25.php. CRISTOBAL L. MIRANDA et al, Prenylflavonoids from Hops Inhibit the Metabolic Activation of the Carcinogenic Heterocyclic Amine 2-Amino-3-methylimidazo[4,5-f]quinoline, Mediated by cDNA-Expressed Human CYP1A2, Drug Metab Dispos. 2000 Nov; №28(11), c.1297-302. он-лайн [найдено 13.12.10] [найдено из Интернет] http://dmd.aspetjournals.org/content/28/ll/1297.long. *

Also Published As

Publication number Publication date
JP2010513360A (ja) 2010-04-30
CA2672155A1 (en) 2008-07-03
CA2672155C (en) 2013-10-01
US20100029757A1 (en) 2010-02-04
DE102006062264A1 (de) 2008-06-26
EP2120906A1 (de) 2009-11-25
RU2009128213A (ru) 2011-01-27
JP5513126B2 (ja) 2014-06-04
EP2120906B1 (de) 2015-04-22
WO2008077618A1 (de) 2008-07-03

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