JP5513126B2 - 肝疾患を予防および／または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 - Google Patents

肝疾患を予防および／または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 Download PDF

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JP5513126B2
JP5513126B2 JP2009541912A JP2009541912A JP5513126B2 JP 5513126 B2 JP5513126 B2 JP 5513126B2 JP 2009541912 A JP2009541912 A JP 2009541912A JP 2009541912 A JP2009541912 A JP 2009541912A JP 5513126 B2 JP5513126 B2 JP 5513126B2
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xanthohumol
isoxanthohumol
active substance
liver
weight
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JP2010513360A5 (enExample
JP2010513360A (ja
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ヘレルブランド、クラウス
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フラキサン ゲーエムベーハー ウント コー． カーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3486—Humulus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2009541912A 2006-12-22 2007-12-21 肝疾患を予防および／または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 Expired - Fee Related JP5513126B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006062264.2 2006-12-22
DE102006062264A DE102006062264A1 (de) 2006-12-22 2006-12-22 Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen
PCT/EP2007/011358 WO2008077618A1 (de) 2006-12-22 2007-12-21 Verwendung von xanthohumol bzw. isoxanthohumol als wirkstoff zur vorbeugung und/oder bekämpfung von lebererkrankungen

Publications (3)

Publication Number Publication Date
JP2010513360A JP2010513360A (ja) 2010-04-30
JP2010513360A5 JP2010513360A5 (enExample) 2011-01-13
JP5513126B2 true JP5513126B2 (ja) 2014-06-04

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JP2009541912A Expired - Fee Related JP5513126B2 (ja) 2006-12-22 2007-12-21 肝疾患を予防および／または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用

Country Status (7)

Country Link
US (1) US20100029757A1 (enExample)
EP (1) EP2120906B1 (enExample)
JP (1) JP5513126B2 (enExample)
CA (1) CA2672155C (enExample)
DE (1) DE102006062264A1 (enExample)
RU (1) RU2454996C2 (enExample)
WO (1) WO2008077618A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010323066B2 (en) 2009-11-26 2014-12-11 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
US9221751B2 (en) 2009-11-26 2015-12-29 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
US10722575B2 (en) 2009-11-26 2020-07-28 Genfit Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
US9358185B2 (en) 2012-06-18 2016-06-07 3M Innovative Properties Company Powder composition for air polishing the surface of hard dental tissue
US9782362B2 (en) * 2012-07-26 2017-10-10 Ta-Xan Ag Uses of compositions containing a roasted extract and xanthohumol
EP2931171B1 (en) 2012-12-17 2018-08-15 3M Innovative Properties Company Device for dispensing a dental material with locking mechanism
EP2742897A1 (en) 2012-12-17 2014-06-18 3M Innovative Properties Company Nozzle head, hand piece and powder jet device for applying a dental material
EP2742898A1 (en) 2012-12-17 2014-06-18 3M Innovative Properties Company Powder jet device for dispensing a dental material
JP2018519342A (ja) * 2015-07-02 2018-07-19 フラクサン ゲーエムベーハー ウント コー． カーゲー ホップに基づく物質およびその物質の使用
US11066629B2 (en) * 2016-12-20 2021-07-20 Suntory Holdings Limited Lipid metabolism-promoting composition including isoxanthohumol
PL3651805T3 (pl) 2017-07-11 2024-04-08 Aquanova Ag Solubilizator z kurkuminą i co najmniej jedną inną substancją czynną
EP3820527B1 (de) 2018-07-11 2023-08-23 Aquanova AG Xanthohumol-solubilisat
JPWO2020031952A1 (ja) * 2018-08-10 2021-08-26 サントリーホールディングス株式会社 血糖値上昇抑制用組成物及び血糖値上昇抑制方法
WO2020031957A1 (ja) * 2018-08-10 2020-02-13 サントリーホールディングス株式会社 腸内環境改善用組成物及び腸内細菌叢改善方法
JP7307073B2 (ja) * 2018-08-10 2023-07-11 サントリーホールディングス株式会社 尿酸排出促進用組成物、ｕｒａｔ１阻害用組成物及び血中尿酸値低下用組成物
CN112584709A (zh) * 2018-08-10 2021-03-30 三得利控股株式会社 微生物增殖抑制剂、微生物污染防止方法及饮料
WO2022173750A1 (en) 2021-02-09 2022-08-18 Oregon State University Xanthohumol derivatives and methods for making and using
JP2024524774A (ja) * 2021-07-09 2024-07-05 イノックス・コーポレイション がんの治療に使用するためのプレニル化カルコンおよびフラボノイド組成物

Family Cites Families (14)

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JPH07285856A (ja) 1994-04-21 1995-10-31 Hoechst Japan Ltd 骨粗鬆症治療剤
RU2232016C2 (ru) * 1996-08-30 2004-07-10 эНПиэС ФАМЭСЬЮТИКЭЛС, ИНК. Изовалерамид-антиспастическое и противосудорожное средство, экстракт из растения семейства valerianaceae или хмеля - средство для лечения симптома спастичности и способ устранения этого симптома, способ лечения патологии, снимаемой центрально-опосредованным снижением мышечного тонуса
JP2003504327A (ja) 1999-07-08 2003-02-04 プレンダーガスト、パトリック、ティ． 感染症の治療を目的としたフラボン類、クマリン類および関連化合物の使用
JP3293601B2 (ja) * 1999-09-03 2002-06-17 松下電器産業株式会社 管球およびその製造方法
EP1277473A4 (en) * 2000-04-10 2005-12-28 Takara Bio Inc REMEDIES
BR0208418A (pt) * 2001-04-05 2004-03-30 Unilever Nv Uso de isoxantohumol e/ou xantohumol, método para administrar isoxantohumol e/ou xantohumol a seres humanos em necessidade de receber um componente ani-inflamatório ou anti-envelhecimento, e, produto alimentìcio
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DE102006062264A1 (de) 2008-06-26
RU2454996C2 (ru) 2012-07-10
JP2010513360A (ja) 2010-04-30
RU2009128213A (ru) 2011-01-27
EP2120906B1 (de) 2015-04-22
CA2672155C (en) 2013-10-01
WO2008077618A1 (de) 2008-07-03
EP2120906A1 (de) 2009-11-25
US20100029757A1 (en) 2010-02-04
CA2672155A1 (en) 2008-07-03

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