JP2010513360A5 - - Google Patents
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- Publication number
- JP2010513360A5 JP2010513360A5 JP2009541912A JP2009541912A JP2010513360A5 JP 2010513360 A5 JP2010513360 A5 JP 2010513360A5 JP 2009541912 A JP2009541912 A JP 2009541912A JP 2009541912 A JP2009541912 A JP 2009541912A JP 2010513360 A5 JP2010513360 A5 JP 2010513360A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- liver disease
- preparation according
- food
- active substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- YKGCBLWILMDSAV-GOSISDBHSA-N Isoxanthohumol Natural products O(C)c1c2C(=O)C[C@H](c3ccc(O)cc3)Oc2c(C/C=C(\C)/C)c(O)c1 YKGCBLWILMDSAV-GOSISDBHSA-N 0.000 claims 6
- 208000019423 liver disease Diseases 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 5
- FUSADYLVRMROPL-UHFFFAOYSA-N demethylxanthohumol Natural products CC(C)=CCC1=C(O)C=C(O)C(C(=O)C=CC=2C=CC(O)=CC=2)=C1O FUSADYLVRMROPL-UHFFFAOYSA-N 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- YKGCBLWILMDSAV-SFHVURJKSA-N isoxanthohumol Chemical compound C1([C@H]2OC=3C(CC=C(C)C)=C(O)C=C(C=3C(=O)C2)OC)=CC=C(O)C=C1 YKGCBLWILMDSAV-SFHVURJKSA-N 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- ORXQGKIUCDPEAJ-YRNVUSSQSA-N xanthohumol Chemical compound COC1=CC(O)=C(CC=C(C)C)C(O)=C1C(=O)\C=C\C1=CC=C(O)C=C1 ORXQGKIUCDPEAJ-YRNVUSSQSA-N 0.000 claims 3
- UVBDKJHYMQEAQV-UHFFFAOYSA-N xanthohumol Natural products OC1=C(CC=C(C)C)C(OC)=CC(OC)=C1C(=O)C=CC1=CC=C(O)C=C1 UVBDKJHYMQEAQV-UHFFFAOYSA-N 0.000 claims 3
- 235000008209 xanthohumol Nutrition 0.000 claims 3
- 102000003712 Complement factor B Human genes 0.000 claims 2
- 108090000056 Complement factor B Proteins 0.000 claims 2
- 208000019425 cirrhosis of liver Diseases 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 claims 2
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 206010019799 Hepatitis viral Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 230000037396 body weight Effects 0.000 claims 1
- 230000007882 cirrhosis Effects 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 201000001862 viral hepatitis Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006062264.2 | 2006-12-22 | ||
| DE102006062264A DE102006062264A1 (de) | 2006-12-22 | 2006-12-22 | Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen |
| PCT/EP2007/011358 WO2008077618A1 (de) | 2006-12-22 | 2007-12-21 | Verwendung von xanthohumol bzw. isoxanthohumol als wirkstoff zur vorbeugung und/oder bekämpfung von lebererkrankungen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010513360A JP2010513360A (ja) | 2010-04-30 |
| JP2010513360A5 true JP2010513360A5 (enExample) | 2011-01-13 |
| JP5513126B2 JP5513126B2 (ja) | 2014-06-04 |
Family
ID=39186950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541912A Expired - Fee Related JP5513126B2 (ja) | 2006-12-22 | 2007-12-21 | 肝疾患を予防および／または制御するための、キサントフモールまたはイソキサントフモールの活性物質としての使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100029757A1 (enExample) |
| EP (1) | EP2120906B1 (enExample) |
| JP (1) | JP5513126B2 (enExample) |
| CA (1) | CA2672155C (enExample) |
| DE (1) | DE102006062264A1 (enExample) |
| RU (1) | RU2454996C2 (enExample) |
| WO (1) | WO2008077618A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010323066B2 (en) | 2009-11-26 | 2014-12-11 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| US9221751B2 (en) | 2009-11-26 | 2015-12-29 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| US10722575B2 (en) | 2009-11-26 | 2020-07-28 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
| US9358185B2 (en) | 2012-06-18 | 2016-06-07 | 3M Innovative Properties Company | Powder composition for air polishing the surface of hard dental tissue |
| US9782362B2 (en) * | 2012-07-26 | 2017-10-10 | Ta-Xan Ag | Uses of compositions containing a roasted extract and xanthohumol |
| EP2931171B1 (en) | 2012-12-17 | 2018-08-15 | 3M Innovative Properties Company | Device for dispensing a dental material with locking mechanism |
| EP2742897A1 (en) | 2012-12-17 | 2014-06-18 | 3M Innovative Properties Company | Nozzle head, hand piece and powder jet device for applying a dental material |
| EP2742898A1 (en) | 2012-12-17 | 2014-06-18 | 3M Innovative Properties Company | Powder jet device for dispensing a dental material |
| JP2018519342A (ja) * | 2015-07-02 | 2018-07-19 | フラクサン ゲーエムベーハー ウント コー． カーゲー | ホップに基づく物質およびその物質の使用 |
| US11066629B2 (en) * | 2016-12-20 | 2021-07-20 | Suntory Holdings Limited | Lipid metabolism-promoting composition including isoxanthohumol |
| PL3651805T3 (pl) | 2017-07-11 | 2024-04-08 | Aquanova Ag | Solubilizator z kurkuminą i co najmniej jedną inną substancją czynną |
| EP3820527B1 (de) | 2018-07-11 | 2023-08-23 | Aquanova AG | Xanthohumol-solubilisat |
| JPWO2020031952A1 (ja) * | 2018-08-10 | 2021-08-26 | サントリーホールディングス株式会社 | 血糖値上昇抑制用組成物及び血糖値上昇抑制方法 |
| WO2020031957A1 (ja) * | 2018-08-10 | 2020-02-13 | サントリーホールディングス株式会社 | 腸内環境改善用組成物及び腸内細菌叢改善方法 |
| JP7307073B2 (ja) * | 2018-08-10 | 2023-07-11 | サントリーホールディングス株式会社 | 尿酸排出促進用組成物、ｕｒａｔ１阻害用組成物及び血中尿酸値低下用組成物 |
| CN112584709A (zh) * | 2018-08-10 | 2021-03-30 | 三得利控股株式会社 | 微生物增殖抑制剂、微生物污染防止方法及饮料 |
| WO2022173750A1 (en) | 2021-02-09 | 2022-08-18 | Oregon State University | Xanthohumol derivatives and methods for making and using |
| JP2024524774A (ja) * | 2021-07-09 | 2024-07-05 | イノックス・コーポレイション | がんの治療に使用するためのプレニル化カルコンおよびフラボノイド組成物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07285856A (ja) | 1994-04-21 | 1995-10-31 | Hoechst Japan Ltd | 骨粗鬆症治療剤 |
| RU2232016C2 (ru) * | 1996-08-30 | 2004-07-10 | эНПиэС ФАМЭСЬЮТИКЭЛС, ИНК. | Изовалерамид-антиспастическое и противосудорожное средство, экстракт из растения семейства valerianaceae или хмеля - средство для лечения симптома спастичности и способ устранения этого симптома, способ лечения патологии, снимаемой центрально-опосредованным снижением мышечного тонуса |
| JP2003504327A (ja) | 1999-07-08 | 2003-02-04 | プレンダーガスト、パトリック、ティ． | 感染症の治療を目的としたフラボン類、クマリン類および関連化合物の使用 |
| JP3293601B2 (ja) * | 1999-09-03 | 2002-06-17 | 松下電器産業株式会社 | 管球およびその製造方法 |
| EP1277473A4 (en) * | 2000-04-10 | 2005-12-28 | Takara Bio Inc | REMEDIES |
| BR0208418A (pt) * | 2001-04-05 | 2004-03-30 | Unilever Nv | Uso de isoxantohumol e/ou xantohumol, método para administrar isoxantohumol e/ou xantohumol a seres humanos em necessidade de receber um componente ani-inflamatório ou anti-envelhecimento, e, produto alimentìcio |
| EP1415657A4 (en) * | 2001-07-13 | 2005-09-14 | Takara Bio Inc | DRUG |
| DE10308864B4 (de) | 2003-02-28 | 2007-03-01 | Paulaner Brauerei Gmbh & Co. Kg | Neues Brauverfahren, damit gebrautes Bier und dessen Verwendung |
| EP1543834A1 (en) | 2003-12-16 | 2005-06-22 | Biodynamics | Production of hop extracts having oestrogenic and antiproliferative bioactivity |
| US20060276372A1 (en) | 2005-03-09 | 2006-12-07 | Lockwood Samuel F | Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of proliferative disorders |
| JP2006306800A (ja) * | 2005-04-28 | 2006-11-09 | Kirin Brewery Co Ltd | ファルネソイドｘ受容体活性化剤 |
| CA2617209A1 (en) * | 2005-07-29 | 2007-02-08 | Bioactives, Inc. | Prenylflavonoid formulations |
| JP2009504657A (ja) * | 2005-08-09 | 2009-02-05 | メタプロテオミクス，エルエルシー | ホップ及びアカシア産物によるプロテインキナーゼ調節 |
| JP5246834B2 (ja) * | 2005-12-27 | 2013-07-24 | 独立行政法人産業技術総合研究所 | アディポネクチン産生強化剤 |
-
2006
- 2006-12-22 DE DE102006062264A patent/DE102006062264A1/de not_active Ceased
-
2007
- 2007-12-21 US US12/520,756 patent/US20100029757A1/en not_active Abandoned
- 2007-12-21 WO PCT/EP2007/011358 patent/WO2008077618A1/de not_active Ceased
- 2007-12-21 CA CA2672155A patent/CA2672155C/en not_active Expired - Fee Related
- 2007-12-21 JP JP2009541912A patent/JP5513126B2/ja not_active Expired - Fee Related
- 2007-12-21 EP EP20070857069 patent/EP2120906B1/de not_active Not-in-force
- 2007-12-21 RU RU2009128213/15A patent/RU2454996C2/ru not_active IP Right Cessation