JP2013505233A5 - - Google Patents
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- Publication number
- JP2013505233A5 JP2013505233A5 JP2012529708A JP2012529708A JP2013505233A5 JP 2013505233 A5 JP2013505233 A5 JP 2013505233A5 JP 2012529708 A JP2012529708 A JP 2012529708A JP 2012529708 A JP2012529708 A JP 2012529708A JP 2013505233 A5 JP2013505233 A5 JP 2013505233A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- block copolymer
- block
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- VFTRKSBEFQDZKX-UHFFFAOYSA-N 3,3'-diindolylmethane Chemical compound C1=CC=C2C(CC=3C4=CC=CC=C4NC=3)=CNC2=C1 VFTRKSBEFQDZKX-UHFFFAOYSA-N 0.000 claims description 12
- 229920001400 block copolymer Polymers 0.000 claims description 8
- 239000008194 pharmaceutical composition Substances 0.000 claims description 8
- 239000004480 active ingredient Substances 0.000 claims description 5
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical group CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims description 4
- 125000006353 oxyethylene group Chemical group 0.000 claims description 4
- 230000008685 targeting Effects 0.000 claims description 4
- 230000002209 hydrophobic effect Effects 0.000 claims description 3
- 229920001992 poloxamer 407 Polymers 0.000 claims description 3
- 229940093768 3,3'-diindolylmethane Drugs 0.000 claims description 2
- 235000010045 3,3'-diindolylmethane Nutrition 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 229920002035 Pluronic® L 10 Polymers 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000004581 coalescence Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000008176 lyophilized powder Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 241000700159 Rattus Species 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2009134872/15A RU2409363C9 (ru) | 2009-09-18 | 2009-09-18 | Фармацевтические композиции для пероральной доставки дииндолилметана (dim) и способы применения этих композиций |
| RU2009134872 | 2009-09-18 | ||
| PCT/RU2010/000487 WO2011034465A1 (ru) | 2009-09-18 | 2010-09-07 | Фармацевтическая композиция для пероральной доставки дииндолилметана |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013505233A JP2013505233A (ja) | 2013-02-14 |
| JP2013505233A5 true JP2013505233A5 (enExample) | 2013-09-05 |
Family
ID=43758874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012529708A Pending JP2013505233A (ja) | 2009-09-18 | 2010-09-07 | ３，３’−ジインドリルメタンの経口投与用医薬組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8791150B2 (enExample) |
| EP (1) | EP2478904B1 (enExample) |
| JP (1) | JP2013505233A (enExample) |
| KR (1) | KR20120078722A (enExample) |
| CN (1) | CN102711755A (enExample) |
| CA (1) | CA2774645C (enExample) |
| EA (1) | EA020932B1 (enExample) |
| RU (1) | RU2409363C9 (enExample) |
| UA (1) | UA102187C2 (enExample) |
| WO (1) | WO2011034465A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201105050D0 (en) * | 2011-03-25 | 2011-05-11 | Iiaa Ltd | Pharmaceutical agent |
| RU2494733C1 (ru) | 2012-10-16 | 2013-10-10 | Всеволод Иванович Киселев | Фармацевтическая композиция на основе фитонутриентов с повышенной биодоступностью, обладающая противоопухолевой активностью, и способ ее получения (варианты) |
| WO2015042170A1 (en) | 2013-09-17 | 2015-03-26 | Wayne State University | Compositions and uses of combinations of dim-related indoles and selected anti-androgen compounds |
| ITMI20131924A1 (it) * | 2013-11-20 | 2015-05-21 | Cosmo Technologies Ltd | Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica |
| RU2564438C1 (ru) * | 2014-07-07 | 2015-09-27 | Закрытое акционерное общество "ИльмиксГрупп" (далее - ЗАО "ИльмиксГрупп") | Способ лечения простатической интраэпителиальной неоплазии (пин) |
| AU2016245984B2 (en) | 2015-04-10 | 2021-03-25 | Bioresponse, L.L.C. | Self-emulsifying formulations of DIM-related indoles |
| WO2017001979A1 (en) * | 2015-06-27 | 2017-01-05 | Reform Bio Inc. | Diindolyl methane compositions, formulations and use thereof |
| GB2565492A (en) * | 2016-05-16 | 2019-02-13 | Nordic Labs Ltd | Means for treating sexually-transmitted infectious diseases |
| CA3036201A1 (en) * | 2016-09-15 | 2018-03-22 | Skintech Life Science Limited | Sublingual or buccal administration of dim for treatment of skin diseases |
| JP6644017B2 (ja) * | 2017-03-30 | 2020-02-12 | 長弘生物科技股▲ふん▼有限公司 | ブチリデンフタリドの用途、その使用方法及びそれを使用して医薬組成物を製造する方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277410B1 (en) * | 1992-10-08 | 2001-08-21 | Supratek Pharma Inc. | Copolymer compositions for oral delivery |
| US6086915A (en) * | 1998-04-01 | 2000-07-11 | Bioresponse L.L.C. | Compositions and methods of adjusting steroid hormone metabolism through phytochemicals |
| US7384971B2 (en) * | 1999-09-23 | 2008-06-10 | Bioresponse L.L.C. | Phytochemicals for the treatment of cervical dysplasia |
| US6416793B1 (en) * | 2000-07-11 | 2002-07-09 | Bioresponse, L.L.C. | Formulations and use of controlled-release indole alkaloids |
| CA2565721C (en) * | 2004-05-06 | 2015-10-06 | Bioresponse, L.L.C. | Diindolymethane formulations for the treatment of leiomyomas |
| CA2588052A1 (en) * | 2004-11-30 | 2006-06-08 | Myriad Genetics, Inc. | Therapeutic formulations |
| RU2318509C2 (ru) * | 2006-02-10 | 2008-03-10 | Всеволод Иванович Киселев | Твердая лекарственная форма дииндолилметана для лечения неопластических заболеваний |
| CA2755014A1 (en) * | 2008-03-10 | 2009-09-17 | University Of Louisville Research Foundation, Inc. | Methods and compositions for controlled delivery of phytochemical agents |
-
2009
- 2009-09-18 RU RU2009134872/15A patent/RU2409363C9/ru active
-
2010
- 2010-09-07 JP JP2012529708A patent/JP2013505233A/ja active Pending
- 2010-09-07 CN CN2010800524064A patent/CN102711755A/zh active Pending
- 2010-09-07 WO PCT/RU2010/000487 patent/WO2011034465A1/ru not_active Ceased
- 2010-09-07 CA CA2774645A patent/CA2774645C/en not_active Expired - Fee Related
- 2010-09-07 EP EP10817500.1A patent/EP2478904B1/en not_active Not-in-force
- 2010-09-07 UA UAA201204644A patent/UA102187C2/ru unknown
- 2010-09-07 KR KR1020127010004A patent/KR20120078722A/ko not_active Withdrawn
- 2010-09-07 US US13/377,261 patent/US8791150B2/en not_active Expired - Fee Related
- 2010-09-07 EA EA201200185A patent/EA020932B1/ru not_active IP Right Cessation
-
2014
- 2014-06-20 US US14/310,768 patent/US20140303225A1/en not_active Abandoned
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