CN102711755A - 用于口服3,3’-二吲哚基甲烷的药物组合物 - Google Patents

用于口服3,3’-二吲哚基甲烷的药物组合物 Download PDF

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Publication number
CN102711755A
CN102711755A CN2010800524064A CN201080052406A CN102711755A CN 102711755 A CN102711755 A CN 102711755A CN 2010800524064 A CN2010800524064 A CN 2010800524064A CN 201080052406 A CN201080052406 A CN 201080052406A CN 102711755 A CN102711755 A CN 102711755A
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CN
China
Prior art keywords
dim
pharmaceutical composition
pluronic
diindolylmethane
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800524064A
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English (en)
Chinese (zh)
Inventor
V.I.基塞莱夫
I.G.瓦西里瓦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZAKRYTOE AKTSIONERNOE OBSCHESTVO VELES FARMA
Original Assignee
ZAKRYTOE AKTSIONERNOE OBSCHESTVO VELES FARMA
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Filing date
Publication date
Application filed by ZAKRYTOE AKTSIONERNOE OBSCHESTVO VELES FARMA filed Critical ZAKRYTOE AKTSIONERNOE OBSCHESTVO VELES FARMA
Publication of CN102711755A publication Critical patent/CN102711755A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2010800524064A 2009-09-18 2010-09-07 用于口服3,3’-二吲哚基甲烷的药物组合物 Pending CN102711755A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2009134872/15A RU2409363C9 (ru) 2009-09-18 2009-09-18 Фармацевтические композиции для пероральной доставки дииндолилметана (dim) и способы применения этих композиций
RU2009134872 2009-09-18
PCT/RU2010/000487 WO2011034465A1 (ru) 2009-09-18 2010-09-07 Фармацевтическая композиция для пероральной доставки дииндолилметана

Publications (1)

Publication Number Publication Date
CN102711755A true CN102711755A (zh) 2012-10-03

Family

ID=43758874

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800524064A Pending CN102711755A (zh) 2009-09-18 2010-09-07 用于口服3,3’-二吲哚基甲烷的药物组合物

Country Status (10)

Country Link
US (2) US8791150B2 (enExample)
EP (1) EP2478904B1 (enExample)
JP (1) JP2013505233A (enExample)
KR (1) KR20120078722A (enExample)
CN (1) CN102711755A (enExample)
CA (1) CA2774645C (enExample)
EA (1) EA020932B1 (enExample)
RU (1) RU2409363C9 (enExample)
UA (1) UA102187C2 (enExample)
WO (1) WO2011034465A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201105050D0 (en) * 2011-03-25 2011-05-11 Iiaa Ltd Pharmaceutical agent
RU2494733C1 (ru) * 2012-10-16 2013-10-10 Всеволод Иванович Киселев Фармацевтическая композиция на основе фитонутриентов с повышенной биодоступностью, обладающая противоопухолевой активностью, и способ ее получения (варианты)
WO2015042170A1 (en) 2013-09-17 2015-03-26 Wayne State University Compositions and uses of combinations of dim-related indoles and selected anti-androgen compounds
ITMI20131924A1 (it) * 2013-11-20 2015-05-21 Cosmo Technologies Ltd Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica
RU2564438C1 (ru) * 2014-07-07 2015-09-27 Закрытое акционерное общество "ИльмиксГрупп" (далее - ЗАО "ИльмиксГрупп") Способ лечения простатической интраэпителиальной неоплазии (пин)
US9918965B2 (en) 2015-04-10 2018-03-20 Bioresponse, L.L.C. Self-emulsifying formulations of DIM-related indoles
WO2017001979A1 (en) * 2015-06-27 2017-01-05 Reform Bio Inc. Diindolyl methane compositions, formulations and use thereof
RU2018134115A (ru) * 2016-05-16 2020-06-17 Акционерное общество "ВЕЛЕС ФАРМА" Средства для лечения инфекционных заболеваний, передаваемых половым путём
US11331303B2 (en) * 2016-09-15 2022-05-17 Skintech Life Science Limited Sublingual or buccal administration of dim for treatment of skin diseases
JP6644017B2 (ja) * 2017-03-30 2020-02-12 長弘生物科技股▲ふん▼有限公司 ブチリデンフタリドの用途、その使用方法及びそれを使用して医薬組成物を製造する方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999049851A1 (en) * 1998-04-01 1999-10-07 Bioresponse, L.L.C. Compositions and methods of adjusting steroid hormone metabolism through facilitated absorption of hydrophobic dietary compounds
US6277410B1 (en) * 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
US20040072891A1 (en) * 1999-09-23 2004-04-15 Zeligs Michael A. Phytochemicals for the treatment of mastalgia, endometriosis and HPV-related conditions including cervical dysplasia

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416793B1 (en) * 2000-07-11 2002-07-09 Bioresponse, L.L.C. Formulations and use of controlled-release indole alkaloids
US8080577B2 (en) * 2004-05-06 2011-12-20 Bioresponse, L.L.C. Diindolylmethane formulations for the treatment of leiomyomas
US20090048346A1 (en) * 2004-11-30 2009-02-19 Myriad Genetics, Incorporated Therapeutic formulations
RU2318509C2 (ru) * 2006-02-10 2008-03-10 Всеволод Иванович Киселев Твердая лекарственная форма дииндолилметана для лечения неопластических заболеваний
WO2009114525A1 (en) * 2008-03-10 2009-09-17 University Of Louisville Research Foundation, Inc. Methods and compositions for controlled delivery of phytochemical agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277410B1 (en) * 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
WO1999049851A1 (en) * 1998-04-01 1999-10-07 Bioresponse, L.L.C. Compositions and methods of adjusting steroid hormone metabolism through facilitated absorption of hydrophobic dietary compounds
US20040072891A1 (en) * 1999-09-23 2004-04-15 Zeligs Michael A. Phytochemicals for the treatment of mastalgia, endometriosis and HPV-related conditions including cervical dysplasia

Also Published As

Publication number Publication date
EP2478904A1 (en) 2012-07-25
US20130065933A1 (en) 2013-03-14
CA2774645A1 (en) 2011-03-24
RU2409363C1 (ru) 2011-01-20
WO2011034465A1 (ru) 2011-03-24
EA020932B1 (ru) 2015-02-27
EP2478904A4 (en) 2013-03-06
JP2013505233A (ja) 2013-02-14
KR20120078722A (ko) 2012-07-10
US8791150B2 (en) 2014-07-29
EP2478904B1 (en) 2016-03-16
EA201200185A1 (ru) 2012-07-30
CA2774645C (en) 2018-10-09
RU2409363C9 (ru) 2013-12-10
UA102187C2 (ru) 2013-06-10
US20140303225A1 (en) 2014-10-09

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Application publication date: 20121003