CN104415320A - 治疗和预防痛风配方 - Google Patents

治疗和预防痛风配方 Download PDF

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CN104415320A
CN104415320A CN201310407088.4A CN201310407088A CN104415320A CN 104415320 A CN104415320 A CN 104415320A CN 201310407088 A CN201310407088 A CN 201310407088A CN 104415320 A CN104415320 A CN 104415320A
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vitamin
gram
uric acid
gout
treatment
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罗云
马利霞
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Leshan Normal University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash

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Abstract

本发明为利用中国传统中药与矿物质和维生素补充剂的复合配方治疗和预防痛风。有效成分包括：生姜、花椒、维生素C、维生素D3、碳酸钙、氧化镁、氧化锌、硫酸铜和硼砂。

Description

治疗和预防痛风配方
  
技术领域
     本发明为中药、矿物质和维他命的复方制剂，用于痛风的预防和治疗。 
  
背景技术
     痛风是由于机体内嘌呤的生物合成代谢增加，尿酸产生过多或尿酸排泄障碍而致血液中尿酸过高，尿酸盐结晶沉积在关节滑膜、滑囊、软骨及其他组织中，引起反复发作的炎性疾病。据估计，仅中国就大约有五千万患者。 
    目前痛风的治疗以缓解临床症状为主。主要是在发作期间服用秋水仙碱和止痛药，以快速消炎，解除痛苦；间歇期间，服用别嘌呤等药物以降低血中尿酸浓度，防止复发。服用降尿酸西药，停药后反弹较快。治疗痛风所用西药都治标不治本，而且具有严重的毒副作用，长期服用将引起肝、肾、脾功能的损害。 
    由于痛风是代谢障碍性疾病，尽管人们采用饮食控制的方法以减少复发，但见效甚微，必须要用药物控制。常用药物有：丙璜舒和苯溴马隆。 
     丙璜舒为尿酸排泄剂，作用机理为抑制肾小管对尿酸的再吸收，增加尿酸从尿液中排出，从而减少血中尿酸的浓度，最终减少尿酸盐沉积在软组织，减少痛风发生；苯溴马隆为苯骈呋喃衍生物，具有抑制肾小管对尿酸的再吸收作用，因而降低血中尿酸浓度。不良反应为粒细胞减少，需定期查血象。 
    急性痛风用的消炎药物： 双氯芬酸钠，非类固醇消炎止痛药；希乐葆，心脏病人及胃病者必须遵照医生指示服用。 
    鉴于上述药物的副作用，许多患者拒绝服用这类药物，而选择敷用中草药，但很多情况下，一处关节炎症消除，另一关节炎症又起，使得患者异常痛苦。 
    服用本发明配方后，痛风消除，并且不复发，患者也无需控制饮食。若服用本配方治疗量的三分之一，则有预防痛风的作用。由于本发明为中药和食物营养剂复方制剂，不仅没有毒副作用，而且还有保健作用。 
  
发明内容
    本发明为中药、矿物质和维他命复方制剂，有效成分包括：生姜、花椒、维生素C、维生素D3、碳酸钙、氧化镁、氧化锌、硫酸铜和硼砂。 
     生姜：为我国常用食材和药材，性温，驱寒，有扩张血管，加快血液循环的作用。痛风是由于尿酸或尿酸盐在关节部位结晶沉积引起，尿酸或尿酸盐会选择温度相对较低的部位沉淀结晶，因此，生姜能阻止尿酸结晶的沉淀；并且，生姜能使血管扩张，血液循环加快，从而使尿酸能及时排出体外。 
    花椒：是我国中华美食烹饪中一种很常用的调味剂，同生姜作用相似，祛除机体的寒气和湿气；同时花椒还能疏通肠胃，促进尿的排泄，从而减少尿酸在血液中的停留。 
    维生素C：维生素C 的缺乏将加重尿酸的生成；大量的试验表明，维生素C 的摄入，能有效的减少痛风的发生。 
    碳酸钙和维生素D3：降低血液的酸度，提高血液中钙的含量。酸度降低，尿酸浓度降低，从而减少尿酸结晶在组织中沉淀。血液中的钙与尿酸结合，使尿酸以尿酸氢钙的形式排出体外。尿酸氢钙在水中的溶解度是尿酸或尿酸氢氨在水中溶解度的二十倍以上，亦是尿酸氢钠的两倍，因此，碳酸钙能降低尿酸结晶沉淀，并能将尿酸及时排出体外，阻止痛风的发生。 
   其它矿物质：氧化镁、氧化锌、硫酸铜和硼砂协同和促进钙的活动，阻止尿酸在骨骼表面结晶沉积。硫酸铜亦能降低黄嘌呤氧化酶的浓度，减少尿酸的生成。 
  
具体实施方式
     实施例1 
      干生姜粉末5克，花椒粉末0.5克，维生素C粉末1.5克，维生素D3 粉末30 微克，碳酸钙粉末4克，氧化镁粉末100毫克，氧化锌粉末20 毫克，无水硫酸铜粉末 2.5毫克，硼砂粉末1.2毫克，混匀后，分为四份，一日内分三次在饭后服下（早餐后服用2份），每次饮水不少于200毫升。预防剂量为该治疗剂量的三分之一。
    实施例2 
      干生姜粉末5克，花椒粉末0.5克，维生素C粉末1.5克，维生素D3 粉末30 微克，碳酸钙粉末4 克，氧化镁 粉末100毫克，氧化锌粉末20毫克，无水硫酸铜粉末 2.5毫克，硼砂粉末1.2毫克，同一定量的食用粘结剂制成40片或40粒，一日内分三次在饭后服下（早餐后服用20片或粒），每次饮水不少于200毫升。预防剂量为该治疗剂量的三分之一。

Claims (5)

1.任何制剂日服量包含干生姜1.0-10克，维生素C 0.5-3.0克，维生素D3 10-60微克，碳酸钙1.0-10.0克等用于治疗和预防痛风。
2.任何制剂日服量包含干生姜1.0-10克，花椒0.1-1.0克，维生素C 0.5-3.0克，维生素D3 5- 30微克，碳酸钙1.0-10.0克等用于治疗和预防痛风。
3.任何制剂日服量包含干生姜1.0-10克，花椒0.1- 1.0克，维生素C 0.5–3.0克，维生素D3 10- 60微克，碳酸钙1.0-10.0克（或相当量的其他碳酸盐或钙盐）, 氧化镁0-200毫克（或等当量的镁盐），氧化锌0-30毫克（或等当量的锌盐），无水硫酸铜0-10毫克（或等当量的铜盐） ，硼砂0-4.0毫克（或等当量的其他含硼化合物）等用于治疗和预防痛风。
4.权利要求1、2或3中，添加糖、淀粉或其他调味剂。
5.权利1、2、3或4中配方用于任何疾病的治疗和预防保健。
CN201310407088.4A 2013-09-10 2013-09-10 治疗和预防痛风配方 Pending CN104415320A (zh)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3090638A1 (de) * 2015-04-20 2016-11-09 Bernd-Michael Löffler Nahrungsergänzung zur behandlung von vitamin-d3-mangelerscheinungen
CN116270952A (zh) * 2023-03-21 2023-06-23 佳木斯大学 一种用于缓解痛风的提取物及其提取方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1739556A (zh) * 2005-09-02 2006-03-01 颜怀玮 防治继发性痛风药食兼用营养素及制造方法
CN102106516A (zh) * 2011-01-25 2011-06-29 天津科技大学 蔬菜提取物抑制黄嘌呤氧化酶的用途及在制备预防和治疗高尿酸血症或痛风食品中的应用
CN103845450A (zh) * 2014-03-26 2014-06-11 沈祥春 山楂在制备治疗高尿酸血症、痛风、肾功能不全药物中的应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1739556A (zh) * 2005-09-02 2006-03-01 颜怀玮 防治继发性痛风药食兼用营养素及制造方法
CN102106516A (zh) * 2011-01-25 2011-06-29 天津科技大学 蔬菜提取物抑制黄嘌呤氧化酶的用途及在制备预防和治疗高尿酸血症或痛风食品中的应用
CN103845450A (zh) * 2014-03-26 2014-06-11 沈祥春 山楂在制备治疗高尿酸血症、痛风、肾功能不全药物中的应用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3090638A1 (de) * 2015-04-20 2016-11-09 Bernd-Michael Löffler Nahrungsergänzung zur behandlung von vitamin-d3-mangelerscheinungen
CN116270952A (zh) * 2023-03-21 2023-06-23 佳木斯大学 一种用于缓解痛风的提取物及其提取方法和应用

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Application publication date: 20150318