RU2362775C1 - Хиназолиновые соединения - Google Patents

Хиназолиновые соединения Download PDF

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RU2362775C1
RU2362775C1 RU2008100767/04A RU2008100767A RU2362775C1 RU 2362775 C1 RU2362775 C1 RU 2362775C1 RU 2008100767/04 A RU2008100767/04 A RU 2008100767/04A RU 2008100767 A RU2008100767 A RU 2008100767A RU 2362775 C1 RU2362775 C1 RU 2362775C1
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bromo
azaindole
azaindoline
obtaining
stage
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Лоран Франсуа Андре ЭННЕКЕН (GB)
Лоран Франсуа Андре ЭННЕКЕН
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Астразенека Аб
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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  • Nitrogen Condensed Heterocyclic Rings (AREA)
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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Изобретение относится к способу получения 5-бром-7-азаиндола, который предусматривает: стадия 1: восстановление 7-азаиндола, получая 7-азаиндолин; стадия 2: бромирование 7-азаиндолина, получая 5-бром-7-азаиндолин; стадия 3: окисление 5-бром-7-азаиндолина, получая 5-бром-7-азаиндол.

Description

Текст описания приведен в факсимильном виде.
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Claims (1)

  1. Способ получения 5-бром-7-азаиндола, который предусматривает: стадия 1: восстановление 7-азаиндола, получая 7-азаиндолин; затем стадия 2: бромирование 7-азаиндолина, получая 5-бром-7-азаиндолин; затем стадия 3: окисление 5-бром-7-азаиндолина, получая 5-бром-7-азаиндол.
RU2008100767/04A 2002-02-01 2003-01-28 Хиназолиновые соединения RU2362775C1 (ru)

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EP02290242.3 2002-02-01
EP02290242 2002-02-01

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US (3) US7268230B2 (ru)
EP (2) EP1474420B1 (ru)
JP (2) JP4608215B2 (ru)
KR (1) KR101093345B1 (ru)
CN (2) CN101607958A (ru)
AR (1) AR038476A1 (ru)
AT (1) ATE549329T1 (ru)
AU (1) AU2003202094B2 (ru)
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NZ (1) NZ534171A (ru)
PL (1) PL371486A1 (ru)
PT (1) PT1474420E (ru)
RU (3) RU2362774C1 (ru)
SI (1) SI1474420T1 (ru)
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UA (1) UA81619C2 (ru)
WO (1) WO2003064413A1 (ru)
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