RU2335495C2 - N-ацильные производные аминокислот, их фармацевтически приемлевые соли, фармацевтическая композиция и применение в качестве гиполипидемических средств - Google Patents
N-ацильные производные аминокислот, их фармацевтически приемлевые соли, фармацевтическая композиция и применение в качестве гиполипидемических средств Download PDFInfo
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- RU2335495C2 RU2335495C2 RU2005118635/04A RU2005118635A RU2335495C2 RU 2335495 C2 RU2335495 C2 RU 2335495C2 RU 2005118635/04 A RU2005118635/04 A RU 2005118635/04A RU 2005118635 A RU2005118635 A RU 2005118635A RU 2335495 C2 RU2335495 C2 RU 2335495C2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
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- Neurology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005118635/04A RU2335495C2 (ru) | 2005-06-15 | 2005-06-15 | N-ацильные производные аминокислот, их фармацевтически приемлевые соли, фармацевтическая композиция и применение в качестве гиполипидемических средств |
| UAA200800495A UA94586C2 (ru) | 2005-06-15 | 2006-06-15 | N-ацильные производные аминокислот, способ их получения, фармацевтическая композиция и их применение как противоаллергических, противовоспалительных и гиполипидемических средств |
| KR1020087001210A KR101402855B1 (ko) | 2005-06-15 | 2006-06-15 | Ｎ-아실계 아미노산 유도체, 이의 생산방법, 약리학적조성물 및 항알러지제, 소염제 및 저지질혈제 형태에서의용도 |
| US11/917,598 US8940780B2 (en) | 2005-06-15 | 2006-06-15 | N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents |
| CN2006800296822A CN101243053B (zh) | 2005-06-15 | 2006-06-15 | N-酰基氨基酸衍生物、其制备方法、药物组合物及其作为抗变应性、抗炎和降血脂药物的用途 |
| EP06757984.7A EP1905763B1 (en) | 2005-06-15 | 2006-06-15 | N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form of anti-allergic, anti-inflammatory and hypolipidemic agents |
| PCT/RU2006/000311 WO2006135280A1 (en) | 2005-06-15 | 2006-06-15 | N-acylic aminoacid derivatives. method for the production thereof, pharmacological composition and the use in the form of anti-allergic, anti-inflammatory and hypolipidemic agents |
| JP2008516776A JP2008543830A (ja) | 2005-06-15 | 2006-06-15 | アミノ酸のｎ−アシル誘導体、その製法、薬理組成物および抗−アレルギー性、抗−炎症性および抗−脂血性薬剤としてのその使用 |
| EA200800054A EA013057B1 (ru) | 2005-06-15 | 2006-06-15 | N-ацильные производные аминокислот, способ их получения, фармацевтическая композиция и применение в качестве противоаллергических, противовоспалительных и гиполипидемических средств |
| CA2612324A CA2612324C (en) | 2005-06-15 | 2006-06-15 | N-acyl derivatives of amino acids, a process for preparation thereof, a pharmaceutical composition and use thereof as antiallergic, anti-inflammatory and hypolipidemic agents |
| US12/764,515 US8318950B2 (en) | 2005-06-15 | 2010-04-21 | N-acyl amino acid derivatives, a method for the preparation thereof, a pharmaceutical composition and use thereof as anti-allergic, anti-inflammatory and hypolipidemic agents |
| JP2013082349A JP5836995B2 (ja) | 2005-06-15 | 2013-04-10 | アミノ酸のｎ−アシル誘導体、その製法、薬理組成物および抗−アレルギー性、抗−炎症性および抗−脂血性薬剤としてのその使用 |
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| RU2008105610/04A Division RU2378284C2 (ru) | 2008-02-13 | 2008-02-13 | Способы получения n-ацильных производных аминокислот (варианты) |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014168523A1 (ru) * | 2013-04-12 | 2014-10-16 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производные бисамидов дикарбоновых кислот, их применение, фармацевтическая композиция на их основе, способы их получения |
| RU2665638C1 (ru) * | 2017-05-24 | 2018-09-03 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидное соединение и его применение в качестве средства для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
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| RU2373934C1 (ru) * | 2008-03-19 | 2009-11-27 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Применение производных глутаровой кислоты или их фармацевтически приемлемых солей в качестве противоаритмических средств |
| US9464306B2 (en) * | 2008-10-29 | 2016-10-11 | Kaneka Corporation | Method for producing L-amino acid |
| WO2010064958A2 (ru) * | 2008-12-01 | 2010-06-10 | Закрытое Акционерное Общество "Мастерклон" | Ингибиторы протеинкиназы с, обладающие противовоспалительным, противоаллергическим и противоастматическим действием |
| UA115431C2 (uk) * | 2011-10-11 | 2017-11-10 | Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" | Застосування глутарилгістаміну для лікування захворювань дихальних шляхів |
| CN102757388B (zh) * | 2012-07-04 | 2015-05-20 | 四川百利药业有限责任公司 | 一种高纯度英加韦林的制备方法 |
| RU2518314C2 (ru) * | 2012-08-30 | 2014-06-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Способ и средство активации irf-3 для лечения и профилактики заболеваний, вызываемых (+) phk-содержащими вирусами |
| JP6741572B2 (ja) | 2013-03-15 | 2020-08-19 | モジュラー ジェネティクス， インコーポレイテッド | アシルアミノ酸の生成 |
| CN103288741B (zh) * | 2013-05-24 | 2015-09-30 | 华南农业大学 | 一种组胺半抗原、人工抗原、抗体及其制备方法与应用 |
| CN105517607A (zh) * | 2013-08-05 | 2016-04-20 | 曼金德公司 | 吹入设备和方法 |
| RU2628800C2 (ru) * | 2014-03-12 | 2017-08-22 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
| CN104119277B (zh) * | 2014-07-16 | 2016-08-17 | 华南农业大学 | 一种直接针对组胺的半抗原、人工抗原、抗体及其制备方法与应用 |
| CN104230833B (zh) * | 2014-10-07 | 2016-01-20 | 张远强 | 含腈基的四氮唑乙酸类化合物、其制备方法及用途 |
| WO2017011592A1 (en) | 2015-07-13 | 2017-01-19 | Modular Genetics, Inc. | Generation of acyl alcohols |
| CN110031583B (zh) * | 2018-12-29 | 2022-01-18 | 浙江工业大学 | 分离测定n-琥珀酰色氨酸对映异构体的液相色谱方法 |
| KR102376756B1 (ko) * | 2019-05-24 | 2022-03-21 | 주식회사 스템디알 | N-아실-아미노산을 유효성분으로 포함하는 천식, 비염 또는 결막염의 예방 또는 치료용 조성물 |
| CA3139470C (en) * | 2019-05-24 | 2024-10-15 | Stemdr Inc. | A composition enabling the prevention or treatment of asthma, rhinitis, or conjunctivitis, comprising N-acylamine acid as the active ingredient. |
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| CA2117199C (en) | 1991-09-09 | 2004-12-28 | Jurgen Michaelis | Method for the treatment of the complications and pathology of diabetes |
| RU2141483C1 (ru) * | 1997-07-04 | 1999-11-20 | Небольсин Владимир Евгеньевич | Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция |
| RU2217196C2 (ru) * | 2002-02-28 | 2003-11-27 | Небольсин Владимир Евгеньевич | Способ индукции дифференцировки клеток |
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- 2006-06-15 UA UAA200800495A patent/UA94586C2/ru unknown
- 2006-06-15 CN CN2006800296822A patent/CN101243053B/zh not_active Expired - Fee Related
- 2006-06-15 EA EA200800054A patent/EA013057B1/ru not_active IP Right Cessation
- 2006-06-15 CA CA2612324A patent/CA2612324C/en not_active Expired - Fee Related
- 2006-06-15 KR KR1020087001210A patent/KR101402855B1/ko not_active Expired - Fee Related
- 2006-06-15 JP JP2008516776A patent/JP2008543830A/ja not_active Withdrawn
- 2006-06-15 WO PCT/RU2006/000311 patent/WO2006135280A1/ru not_active Ceased
- 2006-06-15 EP EP06757984.7A patent/EP1905763B1/en not_active Not-in-force
- 2006-06-15 US US11/917,598 patent/US8940780B2/en not_active Expired - Fee Related
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2010
- 2010-04-21 US US12/764,515 patent/US8318950B2/en not_active Expired - Fee Related
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2013
- 2013-04-10 JP JP2013082349A patent/JP5836995B2/ja not_active Expired - Fee Related
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014168523A1 (ru) * | 2013-04-12 | 2014-10-16 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производные бисамидов дикарбоновых кислот, их применение, фармацевтическая композиция на их основе, способы их получения |
| EA036961B1 (ru) * | 2013-04-12 | 2021-01-20 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производное бисамидов дикарбоновых кислот |
| RU2665638C1 (ru) * | 2017-05-24 | 2018-09-03 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидное соединение и его применение в качестве средства для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
Also Published As
| Publication number | Publication date |
|---|---|
| US8318950B2 (en) | 2012-11-27 |
| US20100267962A1 (en) | 2010-10-21 |
| KR101402855B1 (ko) | 2014-06-03 |
| CA2612324A1 (en) | 2006-12-21 |
| EP1905763B1 (en) | 2019-05-08 |
| JP2008543830A (ja) | 2008-12-04 |
| CN101243053A (zh) | 2008-08-13 |
| UA94586C2 (ru) | 2011-05-25 |
| CN101243053B (zh) | 2012-08-08 |
| US20080319040A1 (en) | 2008-12-25 |
| WO2006135280A1 (en) | 2006-12-21 |
| KR20080039872A (ko) | 2008-05-07 |
| JP2013151551A (ja) | 2013-08-08 |
| EP1905763A1 (en) | 2008-04-02 |
| US8940780B2 (en) | 2015-01-27 |
| EA200800054A1 (ru) | 2008-06-30 |
| EP1905763A4 (en) | 2008-08-27 |
| RU2005118635A (ru) | 2006-11-20 |
| JP5836995B2 (ja) | 2015-12-24 |
| EA013057B1 (ru) | 2010-02-26 |
| CA2612324C (en) | 2014-12-30 |
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