CA2612324C - N-acyl derivatives of amino acids, a process for preparation thereof, a pharmaceutical composition and use thereof as antiallergic, anti-inflammatory and hypolipidemic agents - Google Patents
N-acyl derivatives of amino acids, a process for preparation thereof, a pharmaceutical composition and use thereof as antiallergic, anti-inflammatory and hypolipidemic agents Download PDFInfo
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- CA2612324C CA2612324C CA2612324A CA2612324A CA2612324C CA 2612324 C CA2612324 C CA 2612324C CA 2612324 A CA2612324 A CA 2612324A CA 2612324 A CA2612324 A CA 2612324A CA 2612324 C CA2612324 C CA 2612324C
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- Prior art keywords
- alpha
- allergic
- pharmaceutically acceptable
- glutaryl
- compound
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Classifications
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- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005118635/04A RU2335495C2 (ru) | 2005-06-15 | 2005-06-15 | N-ацильные производные аминокислот, их фармацевтически приемлевые соли, фармацевтическая композиция и применение в качестве гиполипидемических средств |
| RU2005118635 | 2005-06-15 | ||
| PCT/RU2006/000311 WO2006135280A1 (en) | 2005-06-15 | 2006-06-15 | N-acylic aminoacid derivatives. method for the production thereof, pharmacological composition and the use in the form of anti-allergic, anti-inflammatory and hypolipidemic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2612324A1 CA2612324A1 (en) | 2006-12-21 |
| CA2612324C true CA2612324C (en) | 2014-12-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2612324A Expired - Fee Related CA2612324C (en) | 2005-06-15 | 2006-06-15 | N-acyl derivatives of amino acids, a process for preparation thereof, a pharmaceutical composition and use thereof as antiallergic, anti-inflammatory and hypolipidemic agents |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8940780B2 (enExample) |
| EP (1) | EP1905763B1 (enExample) |
| JP (2) | JP2008543830A (enExample) |
| KR (1) | KR101402855B1 (enExample) |
| CN (1) | CN101243053B (enExample) |
| CA (1) | CA2612324C (enExample) |
| EA (1) | EA013057B1 (enExample) |
| RU (1) | RU2335495C2 (enExample) |
| UA (1) | UA94586C2 (enExample) |
| WO (1) | WO2006135280A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2373934C1 (ru) * | 2008-03-19 | 2009-11-27 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Применение производных глутаровой кислоты или их фармацевтически приемлемых солей в качестве противоаритмических средств |
| US9464306B2 (en) * | 2008-10-29 | 2016-10-11 | Kaneka Corporation | Method for producing L-amino acid |
| WO2010064958A2 (ru) * | 2008-12-01 | 2010-06-10 | Закрытое Акционерное Общество "Мастерклон" | Ингибиторы протеинкиназы с, обладающие противовоспалительным, противоаллергическим и противоастматическим действием |
| UA115431C2 (uk) * | 2011-10-11 | 2017-11-10 | Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" | Застосування глутарилгістаміну для лікування захворювань дихальних шляхів |
| CN102757388B (zh) * | 2012-07-04 | 2015-05-20 | 四川百利药业有限责任公司 | 一种高纯度英加韦林的制备方法 |
| RU2518314C2 (ru) * | 2012-08-30 | 2014-06-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Способ и средство активации irf-3 для лечения и профилактики заболеваний, вызываемых (+) phk-содержащими вирусами |
| JP6741572B2 (ja) | 2013-03-15 | 2020-08-19 | モジュラー ジェネティクス， インコーポレイテッド | アシルアミノ酸の生成 |
| RU2665688C2 (ru) * | 2013-04-12 | 2018-09-04 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производные бисамидов дикарбоновых кислот, их применение, фармацевтическая композиция на их основе, способы их получения |
| CN103288741B (zh) * | 2013-05-24 | 2015-09-30 | 华南农业大学 | 一种组胺半抗原、人工抗原、抗体及其制备方法与应用 |
| CN105517607A (zh) * | 2013-08-05 | 2016-04-20 | 曼金德公司 | 吹入设备和方法 |
| RU2628800C2 (ru) * | 2014-03-12 | 2017-08-22 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
| CN104119277B (zh) * | 2014-07-16 | 2016-08-17 | 华南农业大学 | 一种直接针对组胺的半抗原、人工抗原、抗体及其制备方法与应用 |
| CN104230833B (zh) * | 2014-10-07 | 2016-01-20 | 张远强 | 含腈基的四氮唑乙酸类化合物、其制备方法及用途 |
| WO2017011592A1 (en) | 2015-07-13 | 2017-01-19 | Modular Genetics, Inc. | Generation of acyl alcohols |
| RU2665638C1 (ru) * | 2017-05-24 | 2018-09-03 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Амидное соединение и его применение в качестве средства для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами |
| CN110031583B (zh) * | 2018-12-29 | 2022-01-18 | 浙江工业大学 | 分离测定n-琥珀酰色氨酸对映异构体的液相色谱方法 |
| KR102376756B1 (ko) * | 2019-05-24 | 2022-03-21 | 주식회사 스템디알 | N-아실-아미노산을 유효성분으로 포함하는 천식, 비염 또는 결막염의 예방 또는 치료용 조성물 |
| CA3139470C (en) * | 2019-05-24 | 2024-10-15 | Stemdr Inc. | A composition enabling the prevention or treatment of asthma, rhinitis, or conjunctivitis, comprising N-acylamine acid as the active ingredient. |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2117199C (en) | 1991-09-09 | 2004-12-28 | Jurgen Michaelis | Method for the treatment of the complications and pathology of diabetes |
| RU2141483C1 (ru) * | 1997-07-04 | 1999-11-20 | Небольсин Владимир Евгеньевич | Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция |
| RU2217196C2 (ru) * | 2002-02-28 | 2003-11-27 | Небольсин Владимир Евгеньевич | Способ индукции дифференцировки клеток |
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2005
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2006
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2010
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2013
- 2013-04-10 JP JP2013082349A patent/JP5836995B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8318950B2 (en) | 2012-11-27 |
| US20100267962A1 (en) | 2010-10-21 |
| KR101402855B1 (ko) | 2014-06-03 |
| RU2335495C2 (ru) | 2008-10-10 |
| CA2612324A1 (en) | 2006-12-21 |
| EP1905763B1 (en) | 2019-05-08 |
| JP2008543830A (ja) | 2008-12-04 |
| CN101243053A (zh) | 2008-08-13 |
| UA94586C2 (ru) | 2011-05-25 |
| CN101243053B (zh) | 2012-08-08 |
| US20080319040A1 (en) | 2008-12-25 |
| WO2006135280A1 (en) | 2006-12-21 |
| KR20080039872A (ko) | 2008-05-07 |
| JP2013151551A (ja) | 2013-08-08 |
| EP1905763A1 (en) | 2008-04-02 |
| US8940780B2 (en) | 2015-01-27 |
| EA200800054A1 (ru) | 2008-06-30 |
| EP1905763A4 (en) | 2008-08-27 |
| RU2005118635A (ru) | 2006-11-20 |
| JP5836995B2 (ja) | 2015-12-24 |
| EA013057B1 (ru) | 2010-02-26 |
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