RU2310445C2 - Применение гидроксиолеиновой кислоты и родственных соединений при производстве лекарственных средств - Google Patents
Применение гидроксиолеиновой кислоты и родственных соединений при производстве лекарственных средств Download PDFInfo
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- RU2310445C2 RU2310445C2 RU2004114229/15A RU2004114229A RU2310445C2 RU 2310445 C2 RU2310445 C2 RU 2310445C2 RU 2004114229/15 A RU2004114229/15 A RU 2004114229/15A RU 2004114229 A RU2004114229 A RU 2004114229A RU 2310445 C2 RU2310445 C2 RU 2310445C2
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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| ES200102269A ES2186576B1 (es) | 2001-10-11 | 2001-10-11 | Acido 2-hidroxioleico para utilizar como medicamento. |
| ESP200102269 | 2001-10-11 |
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| RU2004114229A RU2004114229A (ru) | 2005-04-20 |
| RU2310445C2 true RU2310445C2 (ru) | 2007-11-20 |
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| RU2004114229/15A RU2310445C2 (ru) | 2001-10-11 | 2002-10-09 | Применение гидроксиолеиновой кислоты и родственных соединений при производстве лекарственных средств |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2513995C2 (ru) * | 2009-03-16 | 2014-04-27 | Липофарма Терапьютикс, С.Л. | Применение 2-гидроксипроизводных полиненасыщенных жирных кислот в качестве лекарственных препаратов |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2229935B1 (es) * | 2003-10-10 | 2006-10-01 | Universitat De Les Illes Balears | Utilizacion del acido hidroxioleico y compuestos analagos del mismo como aditivos alimentarios funcionales. |
| JP2009051732A (ja) * | 2005-12-13 | 2009-03-12 | Meiji Seika Kaisha Ltd | Ｐｐａｒリガンド活性を有する組成物 |
| CN101570481B (zh) * | 2008-04-30 | 2012-02-01 | 上海医药工业研究院 | 一种多羟基长链脂肪酸及其分离提取方法和在抑制芳香化酶活性中的应用 |
| ES2342997B1 (es) * | 2008-12-09 | 2011-06-06 | Universitat De Les Illes Balears | Alpha derivados de acidos grasos cis-monoinsaturados para ser usados como medicamento. |
| WO2011089265A1 (en) | 2010-01-25 | 2011-07-28 | Bridge Bioresearch Plc | Use of fatty acid compounds for lowering blood glucose levels |
| CN101985420B (zh) * | 2010-01-29 | 2014-04-30 | 苏州润新生物科技有限公司 | 油酸酯及其制备方法和在制备用于治疗高血压及其并发症的药物中的应用 |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| WO2013108428A1 (ja) * | 2012-01-19 | 2013-07-25 | 日本水産株式会社 | 食欲抑制剤 |
| WO2013132092A1 (en) | 2012-03-09 | 2013-09-12 | Pensieve International Plc | Use of monounsaturated fatty acid compounds for controlling the body weight of a dog or a cat |
| NZ706067A (en) * | 2012-09-26 | 2016-07-29 | Tangent Reprofiling Ltd | Modulators of androgen synthesis |
| GB201217296D0 (en) | 2012-09-27 | 2012-11-14 | Alta Innovations Ltd | Method of treatment and/or prevention |
| RU2679443C2 (ru) * | 2014-10-21 | 2019-02-11 | Университат Де Лес Ильес Балеарс | Способ синтеза гидрокситриглицеридов и их применение для профилактики и лечения заболеваний |
| US10756968B2 (en) | 2015-01-26 | 2020-08-25 | Rapid7, Inc. | Network resource management devices methods and systems |
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| JPS61297A (ja) * | 1984-06-12 | 1986-01-06 | 日本油脂株式会社 | オレイン酸の製造法 |
| GB8603621D0 (en) | 1986-02-14 | 1986-03-19 | Habib N | Modifying lipid structure of cell membranes |
| JPS6344843A (ja) * | 1986-08-13 | 1988-02-25 | Kao Corp | 油中水中油型乳化油脂組成物 |
| CN1035925C (zh) * | 1988-11-16 | 1997-09-24 | 许正 | 亲细胞非均质分子脂质的制备方法 |
| US5422371A (en) * | 1992-05-27 | 1995-06-06 | Arch Development Corp. | Methods and compositions for inhibiting 5α-reductase activity |
| CN1118228A (zh) * | 1995-03-16 | 1996-03-13 | 姜训书 | 松籽果酱 |
| CN1118218A (zh) * | 1995-03-16 | 1996-03-13 | 姜训书 | 松籽油的制作方法及松籽保健食用油 |
| GB9506837D0 (en) * | 1995-04-03 | 1995-05-24 | Scotia Holdings Plc | Triglycerides |
| ATE235505T1 (de) * | 1995-10-30 | 2003-04-15 | Oleoyl Estrone Developments S | Oleat monoester von estrogenen zur behandlung von fettleibigkeit |
| US5856537A (en) * | 1996-06-26 | 1999-01-05 | The Scripps Research Institute | Inhibitors of oleamide hydrolase |
| DE19727636C1 (de) * | 1997-06-28 | 1998-11-19 | Rwe Dea Ag | Verfahren zur Herstellung von 2-Alkylcarbonsäuren |
| CN1212867A (zh) * | 1997-09-29 | 1999-04-07 | 宋凤亭 | 防治心脑血管疾病的组合物 |
| US6077867A (en) * | 1998-01-21 | 2000-06-20 | Fideline | Pig appeasing pheromones to decrease stress, anxiety and aggressiveness |
| US6214875B1 (en) * | 1998-04-14 | 2001-04-10 | Zhenhua Yang | Anticancer effects of specific branched-chain fatty acids and related production process |
| GB2389788B (en) * | 2000-12-23 | 2005-07-20 | Univ Creighton | Methods for inducing apoptosis and inhibiting proliferation in cancer cells |
| DE10130491A1 (de) * | 2001-06-25 | 2003-04-17 | Heirler Horst | Verwendung von mittelkettigen Triglyceriden zur Prävention und Therapie von Adipositas |
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2001
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- 2002-10-09 CN CN2008100917941A patent/CN101259122B/zh not_active Expired - Fee Related
- 2002-10-09 CN CN2008100917937A patent/CN101259121B/zh not_active Expired - Fee Related
- 2002-10-09 US US10/488,726 patent/US20050014831A1/en not_active Abandoned
- 2002-10-09 WO PCT/ES2002/000475 patent/WO2003030891A1/es active IP Right Grant
- 2002-10-09 CA CA2463348A patent/CA2463348C/en not_active Expired - Lifetime
- 2002-10-09 AT AT02783094T patent/ATE322261T1/de active
- 2002-10-09 JP JP2003533923A patent/JP4737931B2/ja not_active Expired - Lifetime
- 2002-10-09 BR BRPI0213165A patent/BRPI0213165B8/pt not_active IP Right Cessation
- 2002-10-09 DE DE60210488T patent/DE60210488T2/de not_active Expired - Lifetime
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2010
- 2010-11-04 US US12/939,641 patent/US8778995B2/en active Active
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| BANNI S. et al. Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. Nutr Cancer. 2001; 41(1-2):91-7. * |
| ДЖЕНКИНС Г., Хартунг У., «Химия органических лекарственных препаратов», М.: Государственное издательство иностранной литературы, 1949, стр.232-233. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2513995C2 (ru) * | 2009-03-16 | 2014-04-27 | Липофарма Терапьютикс, С.Л. | Применение 2-гидроксипроизводных полиненасыщенных жирных кислот в качестве лекарственных препаратов |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2261752T3 (es) | 2006-11-16 |
| EP1435235A1 (en) | 2004-07-07 |
| CN1688302A (zh) | 2005-10-26 |
| CN101259122B (zh) | 2011-04-06 |
| MXPA04003255A (es) | 2005-01-25 |
| US20110136906A1 (en) | 2011-06-09 |
| PT1435235E (pt) | 2006-08-31 |
| ATE322261T1 (de) | 2006-04-15 |
| CA2463348A1 (en) | 2003-04-17 |
| CN101259121A (zh) | 2008-09-10 |
| BRPI0213165B8 (pt) | 2021-05-25 |
| DE60210488D1 (de) | 2006-05-18 |
| US20050014831A1 (en) | 2005-01-20 |
| DE60210488T2 (de) | 2006-12-14 |
| WO2003030891A1 (es) | 2003-04-17 |
| CN101259121B (zh) | 2011-04-06 |
| JP4737931B2 (ja) | 2011-08-03 |
| EP1435235B1 (en) | 2006-04-05 |
| BR0213165A (pt) | 2004-09-14 |
| CA2463348C (en) | 2011-04-05 |
| US8778995B2 (en) | 2014-07-15 |
| CN100471492C (zh) | 2009-03-25 |
| BRPI0213165B1 (pt) | 2018-01-23 |
| RU2004114229A (ru) | 2005-04-20 |
| CN101259122A (zh) | 2008-09-10 |
| ES2186576A1 (es) | 2003-05-01 |
| ES2186576B1 (es) | 2004-09-16 |
| JP2005527479A (ja) | 2005-09-15 |
| US20090082446A1 (en) | 2009-03-26 |
| US7851507B2 (en) | 2010-12-14 |
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