RU2196139C2 - 1,4,5-тризамещенные производные имидазола, способы их получения и фармацевтическая композиция на их основе - Google Patents

1,4,5-тризамещенные производные имидазола, способы их получения и фармацевтическая композиция на их основе Download PDF

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RU2196139C2
RU2196139C2 RU97113753/04A RU97113753A RU2196139C2 RU 2196139 C2 RU2196139 C2 RU 2196139C2 RU 97113753/04 A RU97113753/04 A RU 97113753/04A RU 97113753 A RU97113753 A RU 97113753A RU 2196139 C2 RU2196139 C2 RU 2196139C2
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Russia
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formula
alkyl
imidazole
compound
fluorophenyl
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RU97113753/04A
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English (en)
Russian (ru)
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RU97113753A (ru
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Джерри Лерой ЭДАМС (US)
Джерри Лерой ЭДАМС
Тимоти Ф. ГАЛЛАГЕР (US)
Тимоти Ф. ГАЛЛАГЕР
Рави Шанкер ГАРИДЖИПАТИ (IN)
Рави Шанкер ГАРИДЖИПАТИ
Джеффри Чарльз БОЕМ (US)
Джеффри Чарльз БОЕМ
Джозеф СИСКО (US)
Джозеф Сиско
Джон Чеунг-Лун ЛИ (US)
Джон Чеунг-Лун ЛИ
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Смитклайн Бичам Корпорейшн
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
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  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
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  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
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  • AIDS & HIV (AREA)
  • Psychiatry (AREA)
RU97113753/04A 1995-01-09 1996-01-11 1,4,5-тризамещенные производные имидазола, способы их получения и фармацевтическая композиция на их основе RU2196139C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36996495A 1995-01-09 1995-01-09
US08/369,964 1995-01-09
US08/472,366 US5593992A (en) 1993-07-16 1995-06-07 Compounds
US08/472,366 1995-06-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2002122174/14A Division RU2002122174A (ru) 1995-01-09 2002-08-15 Способ профилактики и лечения заболевания, опосредуемого csbp/rk/p38 киназой, и способ лечения воспаления

Publications (2)

Publication Number Publication Date
RU97113753A RU97113753A (ru) 1999-06-20
RU2196139C2 true RU2196139C2 (ru) 2003-01-10

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ID=27004764

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Application Number Title Priority Date Filing Date
RU97113753/04A RU2196139C2 (ru) 1995-01-09 1996-01-11 1,4,5-тризамещенные производные имидазола, способы их получения и фармацевтическая композиция на их основе
RU2002122174/14A RU2002122174A (ru) 1995-01-09 2002-08-15 Способ профилактики и лечения заболевания, опосредуемого csbp/rk/p38 киназой, и способ лечения воспаления

Family Applications After (1)

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RU2002122174/14A RU2002122174A (ru) 1995-01-09 2002-08-15 Способ профилактики и лечения заболевания, опосредуемого csbp/rk/p38 киназой, и способ лечения воспаления

Country Status (33)

Country Link
US (5) US5593992A (enrdf_load_stackoverflow)
EP (2) EP1264827A1 (enrdf_load_stackoverflow)
JP (2) JP3330952B2 (enrdf_load_stackoverflow)
CN (1) CN1138546C (enrdf_load_stackoverflow)
AP (1) AP1270A (enrdf_load_stackoverflow)
AR (1) AR002267A1 (enrdf_load_stackoverflow)
AT (1) ATE254613T1 (enrdf_load_stackoverflow)
AU (1) AU705207C (enrdf_load_stackoverflow)
BG (1) BG63769B1 (enrdf_load_stackoverflow)
BR (1) BR9606904A (enrdf_load_stackoverflow)
CA (1) CA2209938A1 (enrdf_load_stackoverflow)
CZ (1) CZ215897A3 (enrdf_load_stackoverflow)
DE (1) DE69630777T2 (enrdf_load_stackoverflow)
DK (1) DK0809499T3 (enrdf_load_stackoverflow)
DZ (1) DZ1961A1 (enrdf_load_stackoverflow)
ES (1) ES2210348T3 (enrdf_load_stackoverflow)
FI (1) FI972901A7 (enrdf_load_stackoverflow)
HU (1) HUP9702409A3 (enrdf_load_stackoverflow)
ID (3) ID23599A (enrdf_load_stackoverflow)
IL (7) IL134323A (enrdf_load_stackoverflow)
IN (3) IN184957B (enrdf_load_stackoverflow)
MA (1) MA23770A1 (enrdf_load_stackoverflow)
MX (1) MX9705142A (enrdf_load_stackoverflow)
NO (3) NO973167L (enrdf_load_stackoverflow)
NZ (1) NZ301204A (enrdf_load_stackoverflow)
OA (1) OA10738A (enrdf_load_stackoverflow)
PL (1) PL322249A1 (enrdf_load_stackoverflow)
PT (1) PT809499E (enrdf_load_stackoverflow)
RU (2) RU2196139C2 (enrdf_load_stackoverflow)
SI (1) SI0809499T1 (enrdf_load_stackoverflow)
SK (1) SK90297A3 (enrdf_load_stackoverflow)
TW (1) TW523511B (enrdf_load_stackoverflow)
WO (1) WO1996021452A1 (enrdf_load_stackoverflow)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2401265C2 (ru) * 2004-06-10 2010-10-10 Айрм Ллк Соединения и композиции в качестве ингибиторов протеинкиназы
RU2418582C1 (ru) * 2010-04-08 2011-05-20 Аверин Константин Михайлович 1,3-диалкилбензимидазолия галогениды - средства для лечения рассеянного склероза
RU2475483C2 (ru) * 2006-04-20 2013-02-20 Янссен Фармацевтика Н.В. Ингибиторы с-fms киназы
RU2813203C2 (ru) * 2019-08-23 2024-02-07 Мотида Фармасьютикал Ко., Лтд. Способ получения гетероциклиденового ацетамидного производного
US12286414B2 (en) 2019-08-23 2025-04-29 Mochida Pharmaceutical Co., Ltd. Method for producing heterocyclidene acetamide derivative

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US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
ATE186551T1 (de) * 1993-09-17 1999-11-15 Smithkline Beecham Corp Medikamente bindendes protein
US6203803B1 (en) 1994-12-14 2001-03-20 Societe L'oreal S.A. Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained
CA2210322A1 (en) * 1995-01-12 1996-07-18 Smithkline Beecham Corporation Novel compounds
EP0737471A3 (fr) * 1995-04-10 2000-12-06 L'oreal Utilisation d'un sel d'une métal alcalino-terreux comme inhibiteur de TNF-alpha dans une composition unique et composition obtenue
US6369068B1 (en) 1995-06-07 2002-04-09 Smithkline Beecham Corporation Amino substituted pyrimidine containing compounds
US5739143A (en) * 1995-06-07 1998-04-14 Smithkline Beecham Corporation Imidazole compounds and compositions
IL118544A (en) 1995-06-07 2001-08-08 Smithkline Beecham Corp History of imidazole, the process for their preparation and the pharmaceutical preparations containing them
FR2740341B1 (fr) * 1995-10-26 1997-12-19 Oreal Utilisation de sel de lanthanide, d'etain, de zinc, de manganese, d'yttrium, de cobalt, de baryum, de strontium dans une composition pour la peau
ZA9610687B (en) * 1995-12-22 1997-09-29 Smithkline Beecham Corp Novel synthesis.
ZA97175B (en) * 1996-01-11 1997-11-04 Smithkline Beecham Corp Novel substituted imidazole compounds.
US6046208A (en) * 1996-01-11 2000-04-04 Smithkline Beecham Corporation Substituted imidazole compounds
AP9700912A0 (en) * 1996-01-11 1997-01-31 Smithkline Beecham Corp Novel cycloalkyl substituted imidazoles
IL125223A0 (en) * 1996-01-11 1999-03-12 Smithkline Beecham Corp Novel substituted imidazole compounds
WO1997032583A1 (en) * 1996-03-08 1997-09-12 Smithkline Beecham Corporation Use of csaidtm compounds as inhibitors of angiogenesis
EP0889888A4 (en) * 1996-03-25 2003-01-08 Smithkline Beecham Corp NEW TREATMENT OF LESIONS IN THE CENTRAL NERVOUS SYSTEM
EP0956018A4 (en) 1996-08-21 2000-01-12 Smithkline Beecham Corp IMIDAZOLE COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE
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