YU75703A - Postupak za pripremanje tetrasupstituisanih derivata imidazola i njihove nove kristalne strukure - Google Patents

Postupak za pripremanje tetrasupstituisanih derivata imidazola i njihove nove kristalne strukure

Info

Publication number
YU75703A
YU75703A YU75703A YUP75703A YU75703A YU 75703 A YU75703 A YU 75703A YU 75703 A YU75703 A YU 75703A YU P75703 A YUP75703 A YU P75703A YU 75703 A YU75703 A YU 75703A
Authority
YU
Yugoslavia
Prior art keywords
imidazole derivatives
preparation
crystalline structures
novel crystalline
tetrasubstituted imidazole
Prior art date
Application number
YU75703A
Other languages
English (en)
Inventor
Hua Zhong
Silke Dubberke
Stefan Muller
Armin Rossler
Thomas W. Schultz
Daniel J. Koray
Thomas Otten
Donald G. Walker
Abdel Abdel-Magid
Original Assignee
Ortho-Mcneil Pharmaceutical Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical Inc. filed Critical Ortho-Mcneil Pharmaceutical Inc.
Publication of YU75703A publication Critical patent/YU75703A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/51—Acetal radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Prikazani pronalazak se odnosi na postupak za pripremanje tetrasupstituisanih derivata imidazola opšte formule (I) u kojoj R1, R2, R3 i R4 su kao što je definisano u opisu. Prikazani pronalazak se dalje odnosi na postupak za pripremanje jedinjenja formule (II) i nove kristalne strukture jedinjenja formule (II).[The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below.The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).
YU75703A 2001-03-26 2002-02-22 Postupak za pripremanje tetrasupstituisanih derivata imidazola i njihove nove kristalne strukure YU75703A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27860701P 2001-03-26 2001-03-26
US10/081,553 US7067671B2 (en) 2001-03-26 2002-02-22 Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof

Publications (1)

Publication Number Publication Date
YU75703A true YU75703A (sh) 2006-05-25

Family

ID=23065636

Family Applications (1)

Application Number Title Priority Date Filing Date
YU75703A YU75703A (sh) 2001-03-26 2002-02-22 Postupak za pripremanje tetrasupstituisanih derivata imidazola i njihove nove kristalne strukure

Country Status (15)

Country Link
US (2) US7067671B2 (sh)
EP (1) EP1392678A2 (sh)
JP (1) JP2005504004A (sh)
KR (1) KR20040005897A (sh)
CN (3) CN1781903A (sh)
BR (1) BR0208462A (sh)
CA (1) CA2442364A1 (sh)
CZ (1) CZ20032871A3 (sh)
HU (1) HUP0303618A3 (sh)
MX (1) MXPA03008727A (sh)
NZ (1) NZ528405A (sh)
RU (1) RU2286342C2 (sh)
SK (1) SK13132003A3 (sh)
WO (1) WO2002076974A2 (sh)
YU (1) YU75703A (sh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4432492B2 (ja) * 2001-10-22 2010-03-17 田辺三菱製薬株式会社 ４−イミダゾリン−２−オン化合物
US7473695B2 (en) 2001-10-22 2009-01-06 Mitsubishi Tanabe Pharma Corporation 4-imidazolin-2-one compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1010969B (de) * 1953-07-03 1957-06-27 Hoffmann La Roche Verfahren zur Herstellung von neuen 2-Imidazolonen
DE2950478A1 (de) * 1979-12-14 1981-06-19 A. Nattermann & Cie GmbH, 5000 Köln 4,5-diaryl-4-imidazolin-2-on-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504677A1 (de) 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
KR100291112B1 (ko) * 1992-02-11 2001-09-17 더 존스 홉킨스 유니버시티 코엔자임에이-독립성트랜스아실라제및혈소판활성화인자억제제
US5593992A (en) 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
US5670527A (en) 1993-07-16 1997-09-23 Smithkline Beecham Corporation Pyridyl imidazole compounds and compositions
ATE244234T1 (de) 1997-04-24 2003-07-15 Ortho Mcneil Pharm Inc Substituierte imidazole zur behandlung von entzündlichen krankheiten
FR2772377B1 (fr) * 1997-12-12 2000-01-07 Synthelabo Derives de 1-(1-h-imidazol-2-yl)pyrrolidines et 1-(1-h-imidazol-2-ylpiperidines), leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
KR20040005897A (ko) 2004-01-16
MXPA03008727A (es) 2004-07-30
CN1511150A (zh) 2004-07-07
JP2005504004A (ja) 2005-02-10
HUP0303618A2 (hu) 2005-04-28
NZ528405A (en) 2005-07-29
RU2286342C2 (ru) 2006-10-27
CA2442364A1 (en) 2002-10-03
RU2003128875A (ru) 2005-04-20
US7132544B2 (en) 2006-11-07
EP1392678A2 (en) 2004-03-03
BR0208462A (pt) 2004-03-02
US20030045723A1 (en) 2003-03-06
US20060030712A1 (en) 2006-02-09
US7067671B2 (en) 2006-06-27
SK13132003A3 (sk) 2004-07-07
CN1800178A (zh) 2006-07-12
WO2002076974A2 (en) 2002-10-03
WO2002076974A3 (en) 2003-02-13
CN1781903A (zh) 2006-06-07
HUP0303618A3 (en) 2005-06-28
CZ20032871A3 (cs) 2004-08-18

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