MXPA03008727A - Procedimiento para la preparacion de derivados de imidazol tetrasubstituidos y estructuras cristalinas novedosas de los mismos. - Google Patents

Procedimiento para la preparacion de derivados de imidazol tetrasubstituidos y estructuras cristalinas novedosas de los mismos.

Info

Publication number
MXPA03008727A
MXPA03008727A MXPA03008727A MXPA03008727A MXPA03008727A MX PA03008727 A MXPA03008727 A MX PA03008727A MX PA03008727 A MXPA03008727 A MX PA03008727A MX PA03008727 A MXPA03008727 A MX PA03008727A MX PA03008727 A MXPA03008727 A MX PA03008727A
Authority
MX
Mexico
Prior art keywords
imidazole derivatives
preparation
crystalline structures
novel crystalline
tetrasubstituted imidazole
Prior art date
Application number
MXPA03008727A
Other languages
English (en)
Inventor
Abdel-Magid Ahmed
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA03008727A publication Critical patent/MXPA03008727A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/51—Acetal radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion se refiere a un procedimiento para preparar derivados de imidazol tetrasubstituidos de la formula general (I) en donde R1, R2, R3, y R4 son como se definen en la especificacion posterior; la presente invencion tambien se refiere a un procedimiento para preparar un compuesto de la formula (II) (ver formula) y estructuras cristalinas novedosas del compuesto de la formula (II).
MXPA03008727A 2001-03-26 2002-02-22 Procedimiento para la preparacion de derivados de imidazol tetrasubstituidos y estructuras cristalinas novedosas de los mismos. MXPA03008727A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27860701P 2001-03-26 2001-03-26
US10/081,553 US7067671B2 (en) 2001-03-26 2002-02-22 Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof
PCT/US2002/005419 WO2002076974A2 (en) 2001-03-26 2002-02-22 Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof

Publications (1)

Publication Number Publication Date
MXPA03008727A true MXPA03008727A (es) 2004-07-30

Family

ID=23065636

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03008727A MXPA03008727A (es) 2001-03-26 2002-02-22 Procedimiento para la preparacion de derivados de imidazol tetrasubstituidos y estructuras cristalinas novedosas de los mismos.

Country Status (15)

Country Link
US (2) US7067671B2 (es)
EP (1) EP1392678A2 (es)
JP (1) JP2005504004A (es)
KR (1) KR20040005897A (es)
CN (3) CN1800178A (es)
BR (1) BR0208462A (es)
CA (1) CA2442364A1 (es)
CZ (1) CZ20032871A3 (es)
HU (1) HUP0303618A3 (es)
MX (1) MXPA03008727A (es)
NZ (1) NZ528405A (es)
RU (1) RU2286342C2 (es)
SK (1) SK13132003A3 (es)
WO (1) WO2002076974A2 (es)
YU (1) YU75703A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04003729A (es) * 2001-10-22 2004-07-23 Tanabe Seiyaku Co Compuestos de 4-imidazolin-2-ona.
US7473695B2 (en) 2001-10-22 2009-01-06 Mitsubishi Tanabe Pharma Corporation 4-imidazolin-2-one compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1010969B (de) 1953-07-03 1957-06-27 Hoffmann La Roche Verfahren zur Herstellung von neuen 2-Imidazolonen
DE2950478A1 (de) 1979-12-14 1981-06-19 A. Nattermann & Cie GmbH, 5000 Köln 4,5-diaryl-4-imidazolin-2-on-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504677A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
WO1993016674A1 (en) * 1992-02-11 1993-09-02 Smithkline Beecham Corporation CoA-IT AND PAF INHIBITORS
US5670527A (en) * 1993-07-16 1997-09-23 Smithkline Beecham Corporation Pyridyl imidazole compounds and compositions
US5593992A (en) 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
US5965583A (en) * 1997-04-24 1999-10-12 Ortho-Mcneil Pharmaceutical, Inc. Substituted imidazoles useful in the treatment of inflammatory disease
FR2772377B1 (fr) 1997-12-12 2000-01-07 Synthelabo Derives de 1-(1-h-imidazol-2-yl)pyrrolidines et 1-(1-h-imidazol-2-ylpiperidines), leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
RU2003128875A (ru) 2005-04-20
WO2002076974A2 (en) 2002-10-03
US20030045723A1 (en) 2003-03-06
HUP0303618A2 (hu) 2005-04-28
RU2286342C2 (ru) 2006-10-27
US7067671B2 (en) 2006-06-27
EP1392678A2 (en) 2004-03-03
SK13132003A3 (sk) 2004-07-07
HUP0303618A3 (en) 2005-06-28
CN1781903A (zh) 2006-06-07
US20060030712A1 (en) 2006-02-09
CN1511150A (zh) 2004-07-07
BR0208462A (pt) 2004-03-02
CN1800178A (zh) 2006-07-12
NZ528405A (en) 2005-07-29
CZ20032871A3 (cs) 2004-08-18
CA2442364A1 (en) 2002-10-03
WO2002076974A3 (en) 2003-02-13
JP2005504004A (ja) 2005-02-10
KR20040005897A (ko) 2004-01-16
YU75703A (sh) 2006-05-25
US7132544B2 (en) 2006-11-07

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