RU2126797C1 - Производные 2,4-оксазолидиндиона или их фармацевтически приемлемая соль, способы их получения, лекарственная композиция, оказывающая гипогликемическое и гиполипидемическое действие, способ снижения содержания сахара и липидов в крови при лечении млекопитающих, страдающих диабетом или гиперлипидимией - Google Patents

Производные 2,4-оксазолидиндиона или их фармацевтически приемлемая соль, способы их получения, лекарственная композиция, оказывающая гипогликемическое и гиполипидемическое действие, способ снижения содержания сахара и липидов в крови при лечении млекопитающих, страдающих диабетом или гиперлипидимией Download PDF

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RU2126797C1
RU2126797C1 RU94006013A RU94006013A RU2126797C1 RU 2126797 C1 RU2126797 C1 RU 2126797C1 RU 94006013 A RU94006013 A RU 94006013A RU 94006013 A RU94006013 A RU 94006013A RU 2126797 C1 RU2126797 C1 RU 2126797C1
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carbon atoms
phenyl
substituted
oxazolidinedione
group
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RU94006013A
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Russian (ru)
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RU94006013A (ru
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Сохда Такаси
Икеда Хитоси
Момосе Ю
Имаи Сатико
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Такеда Кемикал Индастриз, Лтд.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
RU94006013A 1993-02-26 1994-02-25 Производные 2,4-оксазолидиндиона или их фармацевтически приемлемая соль, способы их получения, лекарственная композиция, оказывающая гипогликемическое и гиполипидемическое действие, способ снижения содержания сахара и липидов в крови при лечении млекопитающих, страдающих диабетом или гиперлипидимией RU2126797C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP3823693 1993-02-26
JP05-038236 1993-02-26
JP05-197304 1993-08-09
JP19730493 1993-08-09

Publications (2)

Publication Number Publication Date
RU94006013A RU94006013A (ru) 1995-09-27
RU2126797C1 true RU2126797C1 (ru) 1999-02-27

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Family Applications (1)

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RU94006013A RU2126797C1 (ru) 1993-02-26 1994-02-25 Производные 2,4-оксазолидиндиона или их фармацевтически приемлемая соль, способы их получения, лекарственная композиция, оказывающая гипогликемическое и гиполипидемическое действие, способ снижения содержания сахара и липидов в крови при лечении млекопитающих, страдающих диабетом или гиперлипидимией

Country Status (18)

Country Link
US (4) US5665748A (https=)
EP (1) EP0612743B1 (https=)
JP (2) JP3328720B2 (https=)
KR (1) KR940019699A (https=)
CN (1) CN1098411A (https=)
AT (1) ATE157975T1 (https=)
AU (1) AU673034B2 (https=)
CA (1) CA2116387C (https=)
DE (1) DE69405425T2 (https=)
DK (1) DK0612743T3 (https=)
ES (1) ES2108375T3 (https=)
FI (1) FI940904L (https=)
GR (1) GR3025342T3 (https=)
HU (1) HUT70159A (https=)
NO (1) NO305079B1 (https=)
PH (1) PH31468A (https=)
RU (1) RU2126797C1 (https=)
TW (1) TW268952B (https=)

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RU2296760C2 (ru) * 2001-11-12 2007-04-10 Оно Фармасьютикал Ко., Лтд. Производные соединения карбоновой кислоты и средства, содержащие соединения в качестве активных ингредиентов
RU2355682C2 (ru) * 2004-01-20 2009-05-20 Мерк Энд Ко., Инк. Антидиабетические оксазолидиндионы

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JPH09323930A (ja) * 1996-04-04 1997-12-16 Takeda Chem Ind Ltd 悪液質の予防・治療剤
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
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US5889025A (en) * 1996-05-06 1999-03-30 Reddy's Research Foundation Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
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US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
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US6313113B1 (en) 1997-04-15 2001-11-06 Reddy-Cheminor, Inc. Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
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US6121300A (en) 1998-11-10 2000-09-19 Wagle; Dilip R. Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
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US6399640B1 (en) 1999-06-18 2002-06-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
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JP4316787B2 (ja) * 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、
US7105551B2 (en) 2000-12-20 2006-09-12 Smithkline Beecham Corporation Thiazole derivatives for treating PPAR related disorders
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WO2003059907A1 (en) * 2002-01-17 2003-07-24 Takeda Chemical Industries, Ltd. Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof
TWI327462B (en) * 2002-01-18 2010-07-21 Sumitomo Chemical Co Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same
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WO1992002520A1 (en) * 1990-08-06 1992-02-20 Beecham Group P.L.C. Oxazolidine dione derivatives

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WO1992002520A1 (en) * 1990-08-06 1992-02-20 Beecham Group P.L.C. Oxazolidine dione derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2296760C2 (ru) * 2001-11-12 2007-04-10 Оно Фармасьютикал Ко., Лтд. Производные соединения карбоновой кислоты и средства, содержащие соединения в качестве активных ингредиентов
RU2355682C2 (ru) * 2004-01-20 2009-05-20 Мерк Энд Ко., Инк. Антидиабетические оксазолидиндионы

Also Published As

Publication number Publication date
FI940904A0 (fi) 1994-02-25
GR3025342T3 (en) 1998-02-27
US5972970A (en) 1999-10-26
CA2116387A1 (en) 1994-08-27
DE69405425T2 (de) 1998-03-19
HU9400578D0 (en) 1994-05-30
NO940610D0 (no) 1994-02-23
EP0612743B1 (en) 1997-09-10
US5665748A (en) 1997-09-09
EP0612743A1 (en) 1994-08-31
ES2108375T3 (es) 1997-12-16
HUT70159A (en) 1995-09-28
JP3328720B2 (ja) 2002-09-30
NO940610L (no) 1994-08-29
US6552058B1 (en) 2003-04-22
AU673034B2 (en) 1996-10-24
NO305079B1 (no) 1999-03-29
US6147099A (en) 2000-11-14
CN1098411A (zh) 1995-02-08
DE69405425D1 (de) 1997-10-16
CA2116387C (en) 2003-12-23
ATE157975T1 (de) 1997-09-15
FI940904A7 (fi) 1994-11-29
JPH07165735A (ja) 1995-06-27
KR940019699A (ko) 1994-09-14
DK0612743T3 (da) 1998-04-20
PH31468A (en) 1998-11-03
JP2000191651A (ja) 2000-07-11
FI940904L (fi) 1994-11-29
TW268952B (https=) 1996-01-21
AU5515894A (en) 1994-09-01

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